Navigation Links
UCI researchers find novel memory-enhancing mechanism in brain
Date:12/14/2010

Irvine, Calif., Dec. 14, 2010 UC Irvine researchers have identified a novel mechanism in the brain that boosts memory.

In collaboration with scientists at Germany's University of Munster, the UCI team found that a small protein called neuropeptide S can strengthen and prolong memories of everything from negative events to simple objects.

According to study leader Rainer Reinscheid, UCI associate professor of pharmaceutical sciences, the discovery could provide important clues about how the brain stores memories and also lead to new treatments for Alzheimer's disease, dementia and other cognitive impairments.

"Additionally, it may help us better understand post-traumatic stress disorder, which involves exaggerated memories of traumatic events," he said.

In tests on mice, the researchers observed that if neuropeptide S receptors in the brain were activated immediately after a learning experience, it could be recalled for much longer and with much greater intensity.

This memory enhancement lasted up to a week, Reinscheid said, but when NPS receptor activation was disrupted, the mice didn't remember events as strongly if at all when tested just a day or two later.

Study results, which appear in a Dec. 8 advance online article for the journal Neuropsychopharmacology, are in accordance with Reinscheid's previous findings that NPS causes wakefulness and has a calming effect.

"It appears that the combination of increased alertness and reduced anxiety produced by NPS prepares the animals to learn much better," he said. "Memory is remarkably improved after activation of their NPS system, and the effects are long-lasting, independent of content."


'/>"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
Source:Eurekalert

Page: 1

Related medicine news :

1. Researchers make critical leukemia stem cell discovery
2. U-M researchers discover way to block neurodegeneration in an adult form of Fragile X syndrome
3. Leibniz Prize 2011: 10 researchers awarded €2.5 million ($3.3 million) each
4. Researchers Turn Stem Cells Into Intestinal Tissue in Lab
5. Expert analysis of HER2 tests reveals issues with reliability, Mayo Clinic researchers say
6. Researchers establish new rule to predict risk of stroke, death from surgery that prevents it
7. Hospital shootings rare, but rate of other assults high, Johns Hopkins researchers find
8. Fox Chase researchers uncover new risk factors for brain metastases in breast cancer patients
9. Autism breakthrough: Researchers identify possible treatment for impaired sociability
10. Researchers Assess Gay Youths Mental Health
11. Restless Legs in Pregnancy Likely to Recur, Researchers Say
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... Corner, VA (PRWEB) , ... May 03, 2016 ... ... leading provider of innovative information technology (IT) solutions and digital consulting services to ... Enterprise Information Technology Services (EITS) Indefinite Delivery / Indefinite Quantity (ID/IQ) contract in ...
(Date:5/3/2016)... (PRWEB) , ... May 03, 2016 , ... Huntington ... special type of surgical procedure that can be used to diagnose and treat joint ... can be inserted. These instruments include a special lighting system and lens that illuminate ...
(Date:5/3/2016)... FL (PRWEB) , ... May 03, 2016 , ... Branches, ... both its Grow & Climb children and youth programs in South Miami. Macy’s is ... years. , The Grow Program provides afterschool tutoring, mentoring, enrichment and academic support ...
(Date:5/3/2016)... (PRWEB) , ... May 03, 2016 , ... Finding the right way to address a ... the healthcare industry is now getting on board. , “You do the right thing, at ... cost of care goes down, not up,” said Leonard M. Fromer, MD, FAAFP, from Group ...
(Date:5/3/2016)... ... 2016 , ... LunchSkins is changing the future of ocean plastic ... throw away plastic baggies. The mission-driven bags give back to global leaders in the ... mission is all about reducing global plastic waste and we’ve teamed up ...
Breaking Medicine News(10 mins):
(Date:5/2/2016)... , May 2, 2016 ... to reach USD 11.1 billion by 2024, according ... Research, Inc. Major drivers of the sonography market ... areas and government recommendations for periodic ultrasound screenings ...      (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ) ...
(Date:4/29/2016)... , April 29, 2016 ... Review, H1 2016" market research report that provides ... with comparative analysis at various stages, therapeutics assessment ... of administration (RoA) and molecule type, along with ... It also reviews key players involved in the ...
(Date:4/29/2016)... 2016 Interview ... Sanofi, leader mondial et diversifié ... pour le premier trimestre 2016. Le ... commente les résultats du premier trimestre ... le reste de l,année. ...
Breaking Medicine Technology: