Navigation Links
UCI-led study links prenatal exposure to stress with accelerated cell aging
Date:8/1/2011

Irvine, Calif. Young adults whose mothers experienced psychological trauma during their pregnancies show signs of accelerated aging, a UC Irvine-led study found.

The researchers discovered that this prenatal exposure to stress affected the development of chromosome regions that control cell aging processes. The study results, which appear online this week in the Proceedings of the National Academy of Sciences, point to the importance of maternal health and well-being during pregnancy.

"Our previous research on prenatal stress exposure has shown its effects on long-term metabolic, immune, endocrine and cognitive function," said the paper's lead author, Dr. Pathik D. Wadhwa, UCI professor of psychiatry & human behavior, obstetrics & gynecology, pediatrics, and epidemiology. "But this is the first to show the impact of prenatal stress on cell aging in humans, and it sheds light on an important biological pathway underlying the developmental origins of adult disease risk."

Study participants were healthy 25-year-old women and men born to mothers who had, during pregnancy, experienced psychosocial stress in the form of major, traumatic life events, such as the death or sudden severe illness of an immediate family member. Blood tests revealed that subjects' white blood cells had aged an average of three and a half more years five among women than those of individuals whose mothers had uneventful pregnancies.

This hastened aging was evidenced by the shortened length of telomeres, repetitive stretches of DNA-protein complexes that cap and protect the ends of chromosomes. Telomeres maintain chromosomal stability and control the processes that underlie cellular aging by functioning as a "clock" that regulates how many times a cell can divide. The shorter the telomere strands, the faster the cell ages.

The telomere maintenance system plays an important role in human disease and longevity, and scientists now know that
'/>"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Novel stroke treatment passes safety stage of UCI-led clinical trial
2. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
3. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
4. TV drama can be more persuasive than news program, study finds
5. Study carried out into biological risks of eating reptiles
6. Neuroimaging study may pave way for effective Alzheimers treatments
7. Study finds racial gaps continue in heart disease awareness
8. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
9. First blinded study of venous insufficiency prevalence in MS shows promising results
10. Soothing infants with food focus of childhood obesity study
11. People with anxiety disorder less able to regulate response to negative emotions, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... (PRWEB) July 29, 2014 PeopleKeys today ... designed to teach students how to train and certify ... Certified Behavioral Consultant Trainer , will be taught ... Director of Training John Schindell as a live Tele-course ... , The Certified Behavioral Consultant Trainer course will ...
(Date:7/29/2014)... In today’s world, a good night’s sleep has become ... apnea (a medical problem where the airway collapses during sleep ... the rest they need to face their daily challenges. ... million people in the United States alone have sleep apnea. ... of those treated, many cannot tolerate their prescribed medical device ...
(Date:7/29/2014)... 2014 In its latest blog post, ... and believes that having family close by during a ... whether or not the process is successful, has busted ... difficult to estimate just how damaging and destructive these ... Per Wickstrom . “Not only do they ensnare new ...
(Date:7/29/2014)... Nuanced Media, a leading digital marketing agency, ... Insurance Portability and Accountability Act) certified firm. HIPAA ... transfer of Personal Health Information (PHI). By obtaining ... can effectively serve their medical industry clients. , The ... medical industry specific products such as medical websites ...
(Date:7/29/2014)... 29, 2014 All brides want their ... and memorable. LunaDress’ extensive collection is sure to provide ... not available from local stores. It has recently announced ... additional information, all the new products come with big ... from LunaDress have been working in the ...
Breaking Medicine News(10 mins):Health News:PeopleKeys Announces New Certified Behavioral Consultant Trainer Course 2Health News:PeopleKeys Announces New Certified Behavioral Consultant Trainer Course 3Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Latest Best Drug Rehabilitation Blog Post Busts 4 Big Addiction Myths 2Health News:Latest Best Drug Rehabilitation Blog Post Busts 4 Big Addiction Myths 3Health News:Nuanced Media Web Design Agency Now Hipaa Certified 2Health News:LunaDress’ Summer Sale Has Arrived: All Its Gorgeous Lace Wedding Dresses are Affordable Now 2
... Fashion Show and Armani Exchange model to help DRI ... March 24 Brazilian supermodel Izabel Goulart today announced ... Diabetes Research Institute Foundation, the nonprofit organization whose mission ... Diabetes Research Institute (DRI) at the University of ...
... autism services shares events that raise awareness and provide ... the fastest-growing developmental disability in the U.S., affecting 1 ... diagnosed with an autism spectrum disorder. Autism is more ... It is one of our community,s most urgent needs. ...
... at 11:00 a.m. , Family Research Council ... and Freda McKissic Bush, MD, authors of ... is Affecting Our Children. The authors will explore new ... complex emotional dangers present in adolescent sexual behavior. ...
... On Feb. 1, Starkey Hearing Foundation (SHF) and ... campaign in more than 950 Best Buy locations. With ... loss prevention to young music fans, SoundMatters (TM) ... the word. Taylor Swift leads the list of celebrity ...
... have launched a new foundation to benefit farmworkers, announcing ... three programs related to child care, health care and ... its inaugural projects, the Farmworker Community Support Foundation ... Services and the Redlands Christian Migrant Association ...
... For hundreds of years, doctors, nurses and midwives have ... that signify jaundice, judging that more extensive jaundice carried ... from a blood byproduct, bilirubin, and a child that ... condition called hyperbilirubinemia. , Now pediatric researchers say that ...
Cached Medicine News:Health News:Supermodel Izabel Goulart Partners With Diabetes Research Institute Foundation as International Ambassador 2Health News:Supermodel Izabel Goulart Partners With Diabetes Research Institute Foundation as International Ambassador 3Health News:April is Autism Awareness Month 2Health News:April is Autism Awareness Month 3Health News:FRC to Host Discussion on Harms of Casual Sex 2Health News:Starkey Hearing Foundation Partners With GRAMMY Foundation(R) to Announce SoundMatters(TM) Initiative: GRAMMY-Nominated Artist Taylor Swift, Along With Emerging Artists Crosby Loggins, Jimmy Wayne and GRAMMY-Nominated Sara Bareilles Lead the Way in the Pr 2Health News:Starkey Hearing Foundation Partners With GRAMMY Foundation(R) to Announce SoundMatters(TM) Initiative: GRAMMY-Nominated Artist Taylor Swift, Along With Emerging Artists Crosby Loggins, Jimmy Wayne and GRAMMY-Nominated Sara Bareilles Lead the Way in the Pr 3Health News:Growers Establish Foundation To Help Farmworkers With Child Care, Health Care and Education 2Health News:Growers Establish Foundation To Help Farmworkers With Child Care, Health Care and Education 3Health News:Growers Establish Foundation To Help Farmworkers With Child Care, Health Care and Education 4Health News:Don't rely on jaundiced eye for assessing newborns 2Health News:Don't rely on jaundiced eye for assessing newborns 3
(Date:7/29/2014)... , July 29, 2014  Encision Inc. (OTCQB:ECIA), a ... dangerous stray electrosurgical burns in minimally invasive surgery, today ... ended June 30, 2014. The Company posted ... net loss of $202 thousand, or $(0.02) per share. ... for a net loss of $311 thousand, or $(0.04) ...
(Date:7/29/2014)... , Next phase of ... has commenced , TPM®/Oxycodone Phase 2a trial ... 2014 , TPM®/Oxymorphone Phase 2 trial to ... Australian drug delivery company, Phosphagenics Limited (ASX: ... programs after its recent announcement of a $19.2 million capital raising. ...
(Date:7/29/2014)...   Health 2.0 announces Bernard Tyson , ... Eric Topol , Patrick Soon-Shiong , and Samsung,s ... 8th Annual Fall Conference this coming Sept. 21-24 in ... 2.0 is set to host the very first Wearable Tech ... Consumer Tech & Wearables: Powering Healthy Lifestyles. The ...
Breaking Medicine Technology:Encision Reports First Quarter Fiscal Year 2015 Results 2Encision Reports First Quarter Fiscal Year 2015 Results 3Encision Reports First Quarter Fiscal Year 2015 Results 4Phosphagenics Provides Update on Opioid Patch Program 2Phosphagenics Provides Update on Opioid Patch Program 3Phosphagenics Provides Update on Opioid Patch Program 4Phosphagenics Provides Update on Opioid Patch Program 5Phosphagenics Provides Update on Opioid Patch Program 6Kaiser Permanente CEO to Keynote Health 2.0 8th Annual Fall Conference 2Kaiser Permanente CEO to Keynote Health 2.0 8th Annual Fall Conference 3
... Hospira, Inc. (NYSE: HSP ... announced positive results from a Phase I U.S. clinical ... renal (kidney) dysfunction who have anemia. Hospira,s trial met ... and distribution in the body, for Hospira,s EPO and ...
... 6, 2011 Omthera Pharmaceuticals, Inc., a privately-held emerging ... and Chief Executive Officer, will present at the Rodman ... 2011 at 2:25pm ET at the Waldorf Astoria Hotel ... Pharmaceuticals, Inc. Founded in 2008, Omthera ...
Cached Medicine Technology:Hospira Announces Positive Results From Phase I U.S. Clinical Trial of Biosimilar Erythropoietin in Renal Patients 2Hospira Announces Positive Results From Phase I U.S. Clinical Trial of Biosimilar Erythropoietin in Renal Patients 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: