Navigation Links
UC study: New devices less effective in thwarting brain aneurysm recurrence
Date:2/21/2008

CINCINNATIA retrospective analysis of 100 patients suffering from a ruptured brain aneurysm has found that expensive new coiling devices are no more effective than bare platinum coils at preventing aneurysms from recurring.

A team of researchers from the Neuroscience Institute at the University of Cincinnati (UC) and University Hospital, led by Andrew Ringer, MD, evaluated the risk of intracranial aneurysm recurrence after endovascular treatment with each of three different kinds of coils.

Ringer, the studys principal investigator, is a neurosurgeon with the Mayfield Clinic and is director of endovascular neurosurgery and associate professor of neurosurgery at UC.

The findings are being presented at the International Stroke Conference this week in New Orleans.

An intracranial aneurysm is a balloon-like bulge or blister on an artery in the brain. Aneurysms with thin necks, known as saccular aneurysms, are often treated with a clip. During a craniotomy, a procedure in which the skull is surgically opened, a neurosurgeon places the clip across the neck of the aneurysm, shutting off the aneurysms blood supply.

Surgeons also can use a minimally invasive procedure to treat saccular aneurysms through coiling. A catheter is inserted into an artery in the groin and threaded up through the body to the brain, and a tiny coil is discharged directly into the aneurysm. The minimally invasive procedure enables the patient to avoid surgery and the risks associated with opening the skull.

In an important drawback, however, coils may occasionally compact within the aneurysm. When compaction occurs, blood flows back into the aneurysm, making repeated treatment necessary.

Companies have tried to address the issue of recurrence after coiling by engineering coils using one of two different approaches, Ringer says. One is coated with a polymer designed to promote tissue healing at the neck (opening) of the aneurysm, and one is coated with a gel that, when exposed to blood, is designed to expand inside the aneurysm to fill all the nooks and crannies.

The purpose of our study was to assess the effectiveness of these new treatments, Ringer continues. We found that neither of these newerand more costlycoils performed any better than the bare platinum coils.

To determine whether the new strategies posed an improvement, Ringer and his research team analyzed the outcomes during a 3 -year period of 100 successively treated patients who had suffered ruptured aneurysms of medium size (five to 15 millimeters in diameter).

At the end of one year, the bare platinum coils were associated with the least number of repeated treatments. The percentage requiring repeated treatment was 6.4 percent in the platinum coils group, 11.5 percent in the expanding gel-coating group, and 20.9 percent in the polymer-coating group.

The results, Ringer says, suggest the possibility that a factor, or factors, other than coil-surface coating may be responsible for reducing aneurysm recurrence.


'/>"/>

Contact: Cindy Starr
cstarr@mayfieldclinic.com
513-569-5321
University of Cincinnati
Source:Eurekalert

Related medicine news :

1. Study: low-income women more likely to suffer from postpartum depression
2. Study: Before a CT scan or angiogram, many people should take inexpensive drug to protect kidneys
3. Study: When it comes to physical activity, one size does not fit all
4. U of I study: exercise to avoid gallstones!
5. Geisinger study: PTSD a medical warning sign for long-term health problems
6. Study: Brain connections strengthen during waking hours, weaken during sleep
7. New Study: Screening for Problem Drinking is One of the Most Cost-Effective Clinical Preventive Services
8. New study: US ranks last among other industrialized nations on preventable deaths
9. Study: Short sleep times in patients with chronic medical diagnoses linked to obesity
10. New Lancet Study: Tobacco Control Measures Are Effective and Affordable Strategies to Reduce Chronic Disease Deaths Globally
11. WHO Study: Night Shift Work May Cause Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: