Navigation Links
UC study: New devices less effective in thwarting brain aneurysm recurrence
Date:2/21/2008

CINCINNATIA retrospective analysis of 100 patients suffering from a ruptured brain aneurysm has found that expensive new coiling devices are no more effective than bare platinum coils at preventing aneurysms from recurring.

A team of researchers from the Neuroscience Institute at the University of Cincinnati (UC) and University Hospital, led by Andrew Ringer, MD, evaluated the risk of intracranial aneurysm recurrence after endovascular treatment with each of three different kinds of coils.

Ringer, the studys principal investigator, is a neurosurgeon with the Mayfield Clinic and is director of endovascular neurosurgery and associate professor of neurosurgery at UC.

The findings are being presented at the International Stroke Conference this week in New Orleans.

An intracranial aneurysm is a balloon-like bulge or blister on an artery in the brain. Aneurysms with thin necks, known as saccular aneurysms, are often treated with a clip. During a craniotomy, a procedure in which the skull is surgically opened, a neurosurgeon places the clip across the neck of the aneurysm, shutting off the aneurysms blood supply.

Surgeons also can use a minimally invasive procedure to treat saccular aneurysms through coiling. A catheter is inserted into an artery in the groin and threaded up through the body to the brain, and a tiny coil is discharged directly into the aneurysm. The minimally invasive procedure enables the patient to avoid surgery and the risks associated with opening the skull.

In an important drawback, however, coils may occasionally compact within the aneurysm. When compaction occurs, blood flows back into the aneurysm, making repeated treatment necessary.

Companies have tried to address the issue of recurrence after coiling by engineering coils using one of two different approaches, Ringer says. One is coated with a polymer designed to promote tissue healing at the neck (opening) of the aneurysm, and one is coated with a gel that, when exposed to blood, is designed to expand inside the aneurysm to fill all the nooks and crannies.

The purpose of our study was to assess the effectiveness of these new treatments, Ringer continues. We found that neither of these newerand more costlycoils performed any better than the bare platinum coils.

To determine whether the new strategies posed an improvement, Ringer and his research team analyzed the outcomes during a 3 -year period of 100 successively treated patients who had suffered ruptured aneurysms of medium size (five to 15 millimeters in diameter).

At the end of one year, the bare platinum coils were associated with the least number of repeated treatments. The percentage requiring repeated treatment was 6.4 percent in the platinum coils group, 11.5 percent in the expanding gel-coating group, and 20.9 percent in the polymer-coating group.

The results, Ringer says, suggest the possibility that a factor, or factors, other than coil-surface coating may be responsible for reducing aneurysm recurrence.


'/>"/>

Contact: Cindy Starr
cstarr@mayfieldclinic.com
513-569-5321
University of Cincinnati
Source:Eurekalert

Related medicine news :

1. Study: low-income women more likely to suffer from postpartum depression
2. Study: Before a CT scan or angiogram, many people should take inexpensive drug to protect kidneys
3. Study: When it comes to physical activity, one size does not fit all
4. U of I study: exercise to avoid gallstones!
5. Geisinger study: PTSD a medical warning sign for long-term health problems
6. Study: Brain connections strengthen during waking hours, weaken during sleep
7. New Study: Screening for Problem Drinking is One of the Most Cost-Effective Clinical Preventive Services
8. New study: US ranks last among other industrialized nations on preventable deaths
9. Study: Short sleep times in patients with chronic medical diagnoses linked to obesity
10. New Lancet Study: Tobacco Control Measures Are Effective and Affordable Strategies to Reduce Chronic Disease Deaths Globally
11. WHO Study: Night Shift Work May Cause Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... December 02, 2016 , ... More than half of American teens report losing ... report speaking with their child about sex related topics, less than 60 percent spoke ... proud to announce the launch of its second edition of the “Sexual Wellness” campaign, ...
(Date:12/2/2016)... ... , ... Sourced from the Isbre Springs beneath the 5,000 year old Hardanger ... of just 6 ppm TDS (Total Dissolved Solids) in addition to its excellent taste ... several ShopRite and FoodTown stores in NJ and received rave comments from consumers. , ...
(Date:12/2/2016)... , ... December 02, 2016 , ... ... meals to needy individuals and families from eight different sites throughout Miami-Dade and ... Day. Over 1,000 volunteers worked very hard on Thanksgiving morning by putting together ...
(Date:11/30/2016)... ... November 30, 2016 , ... Northridge dentists, Dr. ... plan for all patients. Understanding that budget can play a part in oral ... of perks, including discounts on many valuable dental treatments. Options for individuals, couples, ...
(Date:11/30/2016)... ... November 30, 2016 , ... In ... been a focus of public policymakers and system stakeholders in many states. To ... its Medical Price Index for Workers’ Compensation, Eighth Edition (MPI-WC) . , ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... , December 2, 2016 On ... Committee honored excellence in research, development and innovation in ... gala dinner was held in the presence of Sergey ... Russian Federation , Natalia Sanina, First ... Mikhail Murashko , Head of Roszdravnadzor, National Service of ...
(Date:12/2/2016)... British Columbia , December 2, 2016 bioLytical ... den INSTI HIV-Selbsttest, bei den Mitgliedern des Apothekenbundes von Kenia eingeführt. ... ... INSTI HIV Self Test! (PRNewsFoto/bioLytical Laboratories) ...      (Photo: http://photos.prnewswire.com/prnh/20161201/444905 ) ...
(Date:12/2/2016)... -- Lianluo Smart Limited (Nasdaq: LLIT ... markets and sells medical devices and wearable sleep ... and international markets, recently attended the 2016 Guangdong ... Forum, co-hosted by the Institute of Interventional Cardiology ... Provincial People,s Hospital and Cardiology Department of Guangdong ...
Breaking Medicine Technology: