Navigation Links
UC San Diego researchers target tumors with tiny 'nanoworms'
Date:5/7/2008

al lymph nodes.

The scientists constructed their nanoworms from spherical iron oxide nanoparticles that join together, like segments of an earthworm, to produce tiny gummy worm-like structures about 30 nanometers longor about 3 million times smaller than an earthworm. Their iron-oxide composition allows the nanoworms to show up brightly in diagnostic devices, specifically the MRI, or magnetic resonance imaging, machines that are used to find tumors.

The iron oxide used in the nanoworms has a property of superparamagnetism, which makes them show up very brightly in MRI, said Sailor. The magnetism of the individual iron oxide segments, typically eight per nanoworm, combine to provide a much larger signal than can be observed if the segments are separated. This translates to a better ability to see smaller tumors, hopefully enabling physicians to make their diagnosis of cancer at earlier stages of development.

In addition to the polymer coating, which is derived from the biopolymer dextran, the scientists coated their nanoworms with a tumor-specific targeting molecule, a peptide called F3, developed in the laboratory of Erkki Ruoslahti, a cell biologist and professor at the Burnham Institute for Medical Research at UC Santa Barbara. This peptide allows the nanoworms to target and home in on tumors.

Because of its elongated shape, the nanoworm can carry many F3 molecules that can simultaneously bind to the tumor surface, said Sailor. And this cooperative effect significantly improves the ability of the nanoworm to attach to a tumor.

The scientists were able to verify in their experiments that their nanoworms homed in on tumor sites by injecting them into the bloodstream of mice with tumors and following the aggregation of the nanoworms on the tumors. They found that the nanoworms, unlike the spherical nanoparticles of similar size that were shuttled out of the blood by the immune system, remained in the bloodstream for hour
'/>"/>

Contact: Kim McDonald
kimmcdonald@ucsd.edu
858-534-7572
University of California - San Diego
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. TriWest On Deck to Support Fleet Week San Diego
2. In Celebration of Breast Cancer Awareness Month, Susan G. Komen for the Cure San Diego Announces Opportunities for San Diegans to Get Involved in the Fight Against Breast Cancer
3. San Diego Dentist Haunted by Smiles in Dominican Republic
4. UC San Diego researchers improve accuracy of breast cancer prognoses
5. Scripps Health Treats More Than 160 Fire Victims at Emergency Departments Across San Diego County
6. San Diego Wildfires Mental Health Fund
7. San Diegos SeQual Technologies Loans 35 Portable Oxygen Units to Evacuees at Qualcomm Stadium
8. Staying sharp in San Diego
9. St. Pauls Senior Homes & Services Welcomes Some of San Diegos Neediest Displaced Seniors
10. ASA San Diego Offers Resources and Information to Families with Autism in Wake of Fires
11. Announcing Always Best Care Senior Services Expansion Into San Diego, California
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2015)... FL (PRWEB) April 26, 2015 India ... pioneered in delivering valuable community services to the Asian ... developmental projects in India for more than two decades. ... hundreds and thousands of subscribers around the world with ... source at that time. The Immigration Law Forum Digest, ...
(Date:4/26/2015)... (PRWEB) April 26, 2015 In an article ... State University evaluated the head-neck biomechanics occurring during the use ... study were able to determine that use of a tablet ... 3 to 5 times - more than when the neck ... for such a study, but pointing out the potential hazards ...
(Date:4/26/2015)... April 26, 2015 The grand celebration got ... by Deb Dettor, CCAR’s Managing Director. Deb then introduced Sandy ... was not in attendance because of his Walk for ... Phil was able to express his gratitude to the volunteers ... for their dedication to carrying out CCAR’s mission. Volunteer ...
(Date:4/25/2015)... DC (PRWEB) April 26, 2015 The ... Seniors (ACE.S) , a national endeavor to prepare nurses ... adults, is a great success, according to a new ... the program's original funding partners. , The project ... of Philadelphia (CCP), under the direction of Elaine Tagliareni, ...
(Date:4/25/2015)... 26, 2015 Avid Collector Andrew Hawley ... Rolling Stones Greensboro Coliseum concert posters. The concert was ... the Stone's Second American Tour. , According to ... out of Baltimore, Maryland. This poster blank was used ... southern cites. Globe uses garish lettering and colors on ...
Breaking Medicine News(10 mins):Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 2Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 2Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 4Health News:The Connecticut Community for Addiction Recovery (CCAR) honors its volunteers during National Volunteer Recognition Week. 2Health News:Hartford Foundation Report Details Success of NLN's Advancing Care Excellence for Seniors (ACE.S) Program 2Health News:Hartford Foundation Report Details Success of NLN's Advancing Care Excellence for Seniors (ACE.S) Program 3
... during the past three decades in at least one ... up the habit, according to research presented at the ... Survey, a population-based, serial cross-sectional study of trends in ... in each of its six surveys. Examining the ...
... treat kidney disease; of that population nearly half of ... Dialysis patients are at elevated risk for sudden ... occur because little research has been done to examine ... population. Northwestern Medicine cardiologist Rod Passman, ...
... the months following the death of a spouse or a child, ... heart attack or sudden cardiac death due to an increased heart ... six months, the study authors said. "While the focus at ... the health and welfare of bereaved survivors should also be of ...
... , SATURDAY, Nov. 13 (HealthDay News) -- When implemented, ... (CPR) can dramatically boost survival rates among people being ... expert report. A case report on the effectiveness ... Saturday at the AHA,s annual meeting in Chicago by ...
... Jenifer Goodwin HealthDay Reporter , FRIDAY, Nov. ... to themselves as "stroke centers of excellence" or "chest ... care for stroke and heart attacks. But current ... of the best cardiovascular or stroke care are falling ...
... in 28 years. At 44, he,s one of the youngest ... of "goat" once they,ve completed 20 or more "Macs", the ... sailed the race every year since he was 16. But, ... was in intensive care awaiting heart transplant following a harrowing ...
Cached Medicine News:Health News:Smoking among some adults dropped dramatically in past three decades 2Health News:Smoking among some adults dropped dramatically in past three decades 3Health News:Smoking among some adults dropped dramatically in past three decades 4Health News:Smoking among some adults dropped dramatically in past three decades 5Health News:Smoking among some adults dropped dramatically in past three decades 6Health News:Patients receiving dialysis are at a heightened risk for sudden cardiac death 2Health News:Patients receiving dialysis are at a heightened risk for sudden cardiac death 3Health News:Death of Loved One May Trigger Elevated Heart Rate 2Health News:CPR Guidelines May Lower Out-of-Hospital Death Rate 2Health News:Setting National Hospital Standards Could Boost Cardiac Care 2Health News:Setting National Hospital Standards Could Boost Cardiac Care 3Health News:Myocarditis can attack hearts without warning 2
(Date:4/24/2015)... , und BARCELONA , ... Nr. 4410) iCAD, Inc. (Nasdaq: ICAD ... Bildanalyse, Lösungen für Behandlungsabläufe und Strahlentherapie für ... heute die sofortige Verfügbarkeit des ersten Xoft ... (eBx ® ) System ® in ...
(Date:4/24/2015)... -- Bayer Corporation hosted its annual "Take Your Child to Work ... headquarters.  This is Bayer,s second "Take Your Child To Work ... campus, and Thursday,s event welcomed 230 children ready to see ... Fortunately, for the kids, this was not just another ... "Science For A Better Life," Bayer made sure that "Take ...
(Date:4/24/2015)... , April 24, 2015   Vestagen Technical Textiles, ... VESTEX ® , has recently received two notable innovation ... global competition that recognizes innovations with potential to create ... last night in New York City ... Material Science "Protection & Safety" category. The awards honor ...
Breaking Medicine Technology:Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 2Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 3Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 4Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 5Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 6Bayer Hosts "Take Your Child to Work Day" 2Bayer Hosts "Take Your Child to Work Day" 3Bayer Hosts "Take Your Child to Work Day" 4VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 2VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: