Navigation Links
UC San Diego researchers target tumors with tiny 'nanoworms'
Date:5/7/2008

Scientists at UC San Diego, UC Santa Barbara and MIT have developed nanometer-sized nanoworms that can cruise through the bloodstream without significant interference from the bodys immune defense system andlike tiny anti-cancer missileshome in on tumors.

Their discovery, detailed in this weeks issue of the journal Advanced Materials, is reminiscent of the 1966 science fiction movie, the Fantastic Voyage, in which a submarine is shrunken to microscopic dimensions, then injected into the bloodstream to remove a blood clot from a diplomats brain.

Using nanoworms, doctors should eventually be able to target and reveal the location of developing tumors that are too small to detect by conventional methods. Carrying payloads targeted to specific features on tumors, these microscopic vehicles could also one day provide the means to more effectively deliver toxic anti-cancer drugs to these tumors in high concentrations without negatively impacting other parts of the body.

Most nanoparticles are recognized by the body's protective mechanisms, which capture and remove them from the bloodstream within a few minutes, said Michael Sailor, a professor of chemistry and biochemistry at UC San Diego who headed the research team. The reason these worms work so well is due to a combination of their shape and to a polymer coating on their surfaces that allows the nanoworms to evade these natural elimination processes. As a result, our nanoworms can circulate in the body of a mouse for many hours.

When attached to drugs, these nanoworms could offer physicians the ability to increase the efficacy of drugs by allowing them to deliver them directly to the tumors, said Sangeeta Bhatia, a physician, bioengineer and a professor of Health Sciences and Technology at MIT who was part of the team. They could decrease the side effects of toxic anti-cancer drugs by limiting their exposure of normal tissues and provide a better diagnosis of tumors and abnorm
'/>"/>

Contact: Kim McDonald
kimmcdonald@ucsd.edu
858-534-7572
University of California - San Diego
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. TriWest On Deck to Support Fleet Week San Diego
2. In Celebration of Breast Cancer Awareness Month, Susan G. Komen for the Cure San Diego Announces Opportunities for San Diegans to Get Involved in the Fight Against Breast Cancer
3. San Diego Dentist Haunted by Smiles in Dominican Republic
4. UC San Diego researchers improve accuracy of breast cancer prognoses
5. Scripps Health Treats More Than 160 Fire Victims at Emergency Departments Across San Diego County
6. San Diego Wildfires Mental Health Fund
7. San Diegos SeQual Technologies Loans 35 Portable Oxygen Units to Evacuees at Qualcomm Stadium
8. Staying sharp in San Diego
9. St. Pauls Senior Homes & Services Welcomes Some of San Diegos Neediest Displaced Seniors
10. ASA San Diego Offers Resources and Information to Families with Autism in Wake of Fires
11. Announcing Always Best Care Senior Services Expansion Into San Diego, California
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... new research study published today in the Journal ... patients older than 50 years with moderate or severe ... , Researchers from the University of Melbourne randomly assigned ... pain to no acupuncture or sham or pretend laser ... with participants and acupuncturists blinded to laser and sham ...
(Date:10/1/2014)... Patients with increased inflammation, including those receiving ... risk of depression. For example, a 6-month treatment ... virus infection causes depression in approximately 30% of ... known as fish oil, have a long list ... heart disease and reducing triglyceride levels. These nutritional ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Familylifeinsurancequotes.org ... find life insurance for senior citizens. , Senior ... Agencies will now sell coverage to seniors who are ... can be purchased without taking a medical examination. , ... purchased online and senior clients can qualify. Having life ...
(Date:10/1/2014)... Bedros Keuilian is not only the ... boot camps, he’s also considered the leading expert on ... out business summits, a line of high-demand fitness marketing ... recent Spike TV reality show to his name. , ... time for personal trainers and fitness business owners to ...
(Date:10/1/2014)... Oregon (PRWEB) October 01, 2014 Phoseon ... solutions , continues to expand the business worldwide. This ... along with additional capacity for manufacturing efforts. The company ... the last five years and expects this growth to ... LED curing technology gains worldwide adoption. , “We ...
Breaking Medicine News(10 mins):Health News:Study finds acupuncture does not improve chronic knee pain 2Health News:Omega-3 fatty acids may prevent some forms of depression 2Health News:Affordable Term Life Insurance - Senior Citizens Can Qualify for Coverage! 2Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 2Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 3Health News:Phoseon Technology Continues to Drive Growth Worldwide 2
... Finn, Jr., C.P.A. ("Finn") announced today that he has ... Brussels Branch. The statement is quoted in its entirety ... is a carbohydrate molecule which inhibits the activity of Galectin-3, ... of human cancers. Prospect reported that GCS-100 could induce ...
... studies show, , FRIDAY, June 5 (HealthDay News) -- One ... often not that interesting. But what if you could dance ... studies suggest that you just might be able to do ... Medicine meeting in Seattle, one study found that salsa dancing ...
... health centres and 680 pharmacies in the region are ready ... June 5 The Extremadura Regional Government of Spain and ... prescription system in 680 pharmacies in Extremadura, where health centres ... dispense prescription medications electronically. , , (Logo: ...
... who undergo myocardial infarction are experiencing onerous fatigue four months ... those who perceive the infarction as a sign of chronic ... and those who believe that the illness has a large ... thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden. ...
... , MENTOR, Ohio, June 5 Join STERIS Isomedix Services ... critical to success in medical device sterilization ... 23, will provide attendees the opportunity to learn about sterilization ... , In addition to the TechTeam experts from STERIS Isomedix ...
... Ostomy Care Nurses Now Available Online , , ... and marketer of innovative medical technologies for community and ... (TM), an online, interactive community and resource. ... ostomy healthcare providers and will be unveiled at the ...
Cached Medicine News:Health News:Ludwig Institute of Cancer Research Ltd., Brussels Branch, Issues Statement Concerning Prospect Therapeutics Inc's. GCS-100 Molecule 2Health News:Finding Fitness on the Dance Floor 2Health News:Finding Fitness on the Dance Floor 3Health News:Spain's Regional Extremadura Government Launches Electronic Prescription System With IBM 2Health News:Fatigue common after myocardial infarction 2Health News:Medical Device Sterilization Seminar Offered by STERIS Isomedix Services 2Health News:Medical Device Sterilization Seminar Offered by STERIS Isomedix Services 3Health News:ConvaTec Launches New Programs to Support and Recognize WOC Nursing 2Health News:ConvaTec Launches New Programs to Support and Recognize WOC Nursing 3
(Date:10/2/2014)... 1, 2014 The global high content screening ... the ,Threat of Obsolescence, wherein technologies as well as ... and biotechnology companies as well as academic and government ... as a powerful research tool in drug discovery. The ... in the high content screening market. In high content ...
(Date:10/1/2014)... Oct. 1, 2014  Dyadic International, Inc. ("Dyadic") ... and proprietary technology used to develop and produce ... chemicals, biopharmaceuticals, and industrial enzymes industries, today announced ... Abengoa Bioenergy for commercial scale production of Abengoa,s ... ethanol, developed under Abengoa,s license agreement with Dyadic. ...
(Date:10/1/2014)... 1, 2014 Trovagene, Inc., (NASDAQ:  TROV) ... that Eli Diamond , MD, Assistant Attending ... presented clinical data from an ongoing study demonstrating ... for the determination of oncogene mutational status in ... results were presented to both treating physicians and ...
Breaking Medicine Technology:High Content Screening Market by Instruments (Cell Imaging and Analysis System), by Applications (Primary and Secondary Screening, Target Identification and Validation, Toxicity Studies, Compound Profiling), Software & Services - Global Forecasts to 2High Content Screening Market by Instruments (Cell Imaging and Analysis System), by Applications (Primary and Secondary Screening, Target Identification and Validation, Toxicity Studies, Compound Profiling), Software & Services - Global Forecasts to 3Dyadic International Reports Licensing Payment For Commercial-Scale Production Of C1-Based Cellulase Enzymes 2Dyadic International Reports Licensing Payment For Commercial-Scale Production Of C1-Based Cellulase Enzymes 3Clinical Performance of Trovagene's Precision Cancer Monitoring Platform Presented at Second Annual International ECD Medical Symposium 2Clinical Performance of Trovagene's Precision Cancer Monitoring Platform Presented at Second Annual International ECD Medical Symposium 3Clinical Performance of Trovagene's Precision Cancer Monitoring Platform Presented at Second Annual International ECD Medical Symposium 4
... The Leukemia & Lymphoma,Society has awarded a $550,000 grant ... Cancer Center at the University of Rochester Medical,Center. Millennium ... the first two years of the five-year program., ... support,Dr. Friedberg,s work on a new targeted treatment for ...
... Medivation, Inc.,(Nasdaq: MDVN ) today announced that ... on Monday, July 7, to discuss top-line results ... of,dimebon(TM) in Huntington,s disease., Teleconference/Webcast Details, ... July 7, at 5:00 p.m. Eastern,time by telephone, ...
Cached Medicine Technology:University of Rochester Researcher Named Millennium Pharmaceuticals Career Development Scholar of The Leukemia & Lymphoma Society 2Medivation to Host Conference Call at 5 p.m. EDT Monday to Discuss Top-Line Phase 2 Study Results in Huntington's Disease 2
... PACHETT 3 uses the exact enhanced corneal ... DGH pachymeters used exclusively by the OHTS ... into the software. The new backlit LCD ... average, standard deviation and IOP correction calculation ...
The Medmont C100 Colour Vision Tester is an electronic colour vision screening device which is used to rapidly detect red/green colour vision deficiencies. Its high sensitivity provides a positive in...
... E300 Corneal Topographer has applications ... clinical procedures including Radial Keratotomy, ... Contact Lens Fitting. Based on ... the E300 analyses an accurate ...
... first Open Bore MR ,Siemens has combined, for ... bore, a very short 125 cm magnet and ... very revolutionary: Open Bore MR. And MAGNETOM Espree, ... A unique Siemens technology, which means faster, more ...
Medicine Products: