Navigation Links
UC San Diego researchers target tumors with tiny 'nanoworms'
Date:5/7/2008

Scientists at UC San Diego, UC Santa Barbara and MIT have developed nanometer-sized nanoworms that can cruise through the bloodstream without significant interference from the bodys immune defense system andlike tiny anti-cancer missileshome in on tumors.

Their discovery, detailed in this weeks issue of the journal Advanced Materials, is reminiscent of the 1966 science fiction movie, the Fantastic Voyage, in which a submarine is shrunken to microscopic dimensions, then injected into the bloodstream to remove a blood clot from a diplomats brain.

Using nanoworms, doctors should eventually be able to target and reveal the location of developing tumors that are too small to detect by conventional methods. Carrying payloads targeted to specific features on tumors, these microscopic vehicles could also one day provide the means to more effectively deliver toxic anti-cancer drugs to these tumors in high concentrations without negatively impacting other parts of the body.

Most nanoparticles are recognized by the body's protective mechanisms, which capture and remove them from the bloodstream within a few minutes, said Michael Sailor, a professor of chemistry and biochemistry at UC San Diego who headed the research team. The reason these worms work so well is due to a combination of their shape and to a polymer coating on their surfaces that allows the nanoworms to evade these natural elimination processes. As a result, our nanoworms can circulate in the body of a mouse for many hours.

When attached to drugs, these nanoworms could offer physicians the ability to increase the efficacy of drugs by allowing them to deliver them directly to the tumors, said Sangeeta Bhatia, a physician, bioengineer and a professor of Health Sciences and Technology at MIT who was part of the team. They could decrease the side effects of toxic anti-cancer drugs by limiting their exposure of normal tissues and provide a better diagnosis of tumors and abnorm
'/>"/>

Contact: Kim McDonald
kimmcdonald@ucsd.edu
858-534-7572
University of California - San Diego
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. TriWest On Deck to Support Fleet Week San Diego
2. In Celebration of Breast Cancer Awareness Month, Susan G. Komen for the Cure San Diego Announces Opportunities for San Diegans to Get Involved in the Fight Against Breast Cancer
3. San Diego Dentist Haunted by Smiles in Dominican Republic
4. UC San Diego researchers improve accuracy of breast cancer prognoses
5. Scripps Health Treats More Than 160 Fire Victims at Emergency Departments Across San Diego County
6. San Diego Wildfires Mental Health Fund
7. San Diegos SeQual Technologies Loans 35 Portable Oxygen Units to Evacuees at Qualcomm Stadium
8. Staying sharp in San Diego
9. St. Pauls Senior Homes & Services Welcomes Some of San Diegos Neediest Displaced Seniors
10. ASA San Diego Offers Resources and Information to Families with Autism in Wake of Fires
11. Announcing Always Best Care Senior Services Expansion Into San Diego, California
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... most persistent and deadliest infectious diseases in the world, ... Scientists who study tuberculosis have long debated its origins. ... in Africa to seals and sea lions that brought ... Native people there before Europeans landed on the continent. ... a Source of New World Human Tuberculosis," was published ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 As concerns ... of power morcellators ( http://www.injurybeacon.com/power-morcellator/ ) in gynecological ... two U.S. Senators from New York are urging the ... recall of the devices. In a letter dated August ... also implored the agency to seriously consider the testimony ...
(Date:8/20/2014)... stimulates stress responses in adults, researchers at Yerkes ... that the amygdala has an inhibitory effect on ... primates. , The results are published this week ... amygdala is a region of the brain known ... and learning about threats. Alterations in the amygdala ...
(Date:8/20/2014)... HealthDay Reporter TUESDAY, Aug. 19, ... a baby,s immune system is twice as common as once ... says. This is the first evaluation of the effect ... as severe combined immunodeficiency (SCID), or "Bubble Boy" disease, the ... by the boy in the bubble, who was born without ...
(Date:8/20/2014)... CA (PRWEB) August 20, 2014 The main ... 12 per diode panel band perfect spectrum that encompasses the ... most likely to use during photosynthesis. A key point ... is that they almost exclusively reside between 440-480 on the ... the red side of the spectrum. The KIND LED K3 ...
Breaking Medicine News(10 mins):Health News:New research shows seals and sea lions likely spread tuberculosis to humans 2Health News:New research shows seals and sea lions likely spread tuberculosis to humans 3Health News:Power Morcellator News: Bernstein Liebhard LLP Notes Senators’ Letter Seeking FDA Morcellator Recall 2Health News:Power Morcellator News: Bernstein Liebhard LLP Notes Senators’ Letter Seeking FDA Morcellator Recall 3Health News:Power Morcellator News: Bernstein Liebhard LLP Notes Senators’ Letter Seeking FDA Morcellator Recall 4Health News:Maturing brain flips function of amygdala in regulating stress hormones 2Health News:Maturing brain flips function of amygdala in regulating stress hormones 3Health News:'Bubble Boy' Disease May Be More Common Than Thought 2Health News:'Bubble Boy' Disease May Be More Common Than Thought 3Health News:Cheap LED Grow Lights Are Quickly Being Replaced by Premium Grow Lights 2
... , FRIDAY, July 31 (HealthDay News) -- A gene associated ... blindness, has been identified by scientists. , The EphA2 gene ... of damaged proteins in the eye. Expression of the EphA2 ... together and cause the eye lens to become cloudy, resulting ...
... , , , LAWRENCE, ... ), a leading manufacturer of innovative dialysis products, today announced that ... Canaccord Adams Global Growth Conference on Tuesday, August 11, 2009 at ... NxStage,s investor presentation is scheduled for Tuesday, August 11th at 10:00 ...
... , , WOODLAND HILLS, Calif., ... provider of advertising and marketing opportunities for national brands in health ... (NYHRC) chain has agreed to join its network. , ... HCMN will immediately begin installation of its static and digital panel ...
... , CHENNAI, India, July 31 ... Children,s Hospital, the,First Standalone Quaternary Care Paediatric Hospital in the ... ) , The Apollo Children,s ... adolescents up to the age of 16 years all,under one ...
... ... section featuring the latest news and trends from the "wellness" world. , ... Seattle, WA (PRWEB) July 31, ... and sleep-deprived society, alternative medicine and natural health have become a great alternative to ...
... ... to disseminating information on dentistry,s role in the recognition and management of snoring and sleep ... the second month in a row. , ... New York, NY (PRWEB) July 31, 2009 -- Snoring Isn,t Sexy, LLC, a ...
Cached Medicine News:Health News:NxStage to Present at the Canaccord Adams Global Growth Conference 2Health News:Health Club Media Network Adds New York Health & Racquet Club 2Health News:Oscar Award Winner, Dr. A.R. Rahman inaugurates Apollo Children's Hospital - the First Standalone Quaternary Care Paediatric Hospital in the Apollo Hospitals Group 2Health News:Natural Healers Launches "Wellness Community Bulletin" 2Health News:Natural Healers Launches "Wellness Community Bulletin" 3Health News:Natural Healers Launches "Wellness Community Bulletin" 4Health News:SnoringIsntSexy.com Tops 21,000 Site Visits for Second Month in a Row 2
(Date:8/20/2014)... , Aug. 20, 2014 Reportlinker.com ... is available in its catalogue: ... Key Trends and Opportunities to 2018 ... Synopsis The report provides in depth market ... personal accident and health insurance segment, including: ...
(Date:8/20/2014)... -- Children aren,t the only segment of our ... disease. The Centers for Disease Control and Prevention ... many adults are not following this advice. ... and the American Lung Association in partnership with ... disease, to talk with their health care provider ...
(Date:8/20/2014)... -- Research and Markets has announced ... Care and Closure Market (Types, Applications, End User ... Profiles, Demand, Insights, Analysis, Research, Report, Opportunities, Segmentation ... their offering. The new report ... (types, applications, end user and geography) - Size, ...
Breaking Medicine Technology:Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 2Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 3Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 4Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 5Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 6Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 7Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 8Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 9Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 10Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 11Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 12Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 13Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 14Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 15Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 16Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 17Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 18Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 19Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 20Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 21Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 22Personal Accident and Health Insurance in France, Key Trends and Opportunities to 2018 23American Lung Association Urges Adults with Lung Disease to Consult their Health Care Provider to Stay Current on Vaccinations 2American Lung Association Urges Adults with Lung Disease to Consult their Health Care Provider to Stay Current on Vaccinations 3Global Advanced Wound Care and Closure Market (Types, Applications, End User and Geography) - Forecast to 2020 2
... Coast Dental Services, Inc., announced today that it ... of Dental Technology, Inc. (DTI), doing business as SmileCare, ... care service plan. DTI and its subsidiaries operate 57 ... 1,200 staff members, including 130 dentists.  The transaction is ...
... The Food and Drug Administration says some companies are ... falsely claim to treat, prevent, or cure STDs. Are ... big risk unless you see a healthcare provider who ... http://photos.prnewswire.com/prnh/20090824/FDALOGO ) View a video, slideshow, and ...
Cached Medicine Technology:Coast Dental to Acquire the Assets of SmileCare 2
Female Mini-VEST, Front Closure, X-Firm...
For Lipoplasty or surgery of abdomen, flanks and midriff...
Female High Waist Briefs...
Short-Sleeve Bolero for targeted compression in the upper arms, back and shoulder areas. Plush-shielded hook and eye front closure for comfort and convenient application....
Medicine Products: