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UC San Diego researcher awarded $5.3 million for breast cancer survivorship study
Date:6/23/2010

The University of California, San Diego School of Medicine has received a $5.3 million grant from the National Cancer Institute to conduct and lead a first-of-its-kind, four-year clinical trial to show the effects of weight loss and increased physical activity on quality of life and on co-existing medical conditions in overweight breast cancer survivors.

This trial is designed as a vanguard component of a larger study that will examine the effect of weight loss on recurrence risk for breast cancer survivors.

Cheryl Rock, PhD, RD, professor of Family and Preventive Medicine at the UCSD School of Medicine, will lead a multi-disciplinary team of experts representing five leading NCI-designated Comprehensive Cancer Centers including the Moores UCSD Cancer Center in this trial, also known as the ENERGY (Exercise and Nutrition to Enhance Recovery and Good Health for You) study.

"Excess body fat is a major adverse prognostic factor for women with both pre- and postmenopausal breast cancer," said Rock. "Up to 30 percent of breast cancer survivors experience anxiety or depression that persists after the completion of treatment. We believe weight loss and increased physical activity in overweight breast cancer survivors will have a positive effect on psychosocial problems and co-existing medical conditions, and may possibly reduce the risk of breast cancer recurrence."

Combining the investigators' experience in diet and exercise, cancer survivorship, nutritional epidemiology, breast oncology trials and breast cancer outcomes research, the team will conduct a randomized, controlled study that will track and measure improvements in quality of life and co-existing medical conditions in 800 overweight or obese breast cancer survivors.

Participants must be at least 21 years old and have been diagnosed with stage I, II, or IIIA breast cancer. They will be involved in a two-year active intervention program.

The weight-loss int
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Contact: Karen Shea
kshea@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert

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