Navigation Links
UC San Diego researcher awarded $5.3 million for breast cancer survivorship study
Date:6/23/2010

The University of California, San Diego School of Medicine has received a $5.3 million grant from the National Cancer Institute to conduct and lead a first-of-its-kind, four-year clinical trial to show the effects of weight loss and increased physical activity on quality of life and on co-existing medical conditions in overweight breast cancer survivors.

This trial is designed as a vanguard component of a larger study that will examine the effect of weight loss on recurrence risk for breast cancer survivors.

Cheryl Rock, PhD, RD, professor of Family and Preventive Medicine at the UCSD School of Medicine, will lead a multi-disciplinary team of experts representing five leading NCI-designated Comprehensive Cancer Centers including the Moores UCSD Cancer Center in this trial, also known as the ENERGY (Exercise and Nutrition to Enhance Recovery and Good Health for You) study.

"Excess body fat is a major adverse prognostic factor for women with both pre- and postmenopausal breast cancer," said Rock. "Up to 30 percent of breast cancer survivors experience anxiety or depression that persists after the completion of treatment. We believe weight loss and increased physical activity in overweight breast cancer survivors will have a positive effect on psychosocial problems and co-existing medical conditions, and may possibly reduce the risk of breast cancer recurrence."

Combining the investigators' experience in diet and exercise, cancer survivorship, nutritional epidemiology, breast oncology trials and breast cancer outcomes research, the team will conduct a randomized, controlled study that will track and measure improvements in quality of life and co-existing medical conditions in 800 overweight or obese breast cancer survivors.

Participants must be at least 21 years old and have been diagnosed with stage I, II, or IIIA breast cancer. They will be involved in a two-year active intervention program.

The weight-loss intervention uses a cognitive-behavioral group-based program, telephone counseling and home-based support that has been developed and tested in previous successful studies conducted by the ENERGY study's investigators.

"There are various goals of the ENERGY study," Rock said. "First, we are aiming for weight loss and maintenance among all 800 subjects, with a primary hypothesis that they will achieve an average weight reduction of at least seven percent of initial weight. We're also assessing the impact of the intervention on their quality of life, particularly physical functioning and fatigue." She added that the researchers will also conduct a cost-effectiveness analysis that includes an assessment of the impact of the intervention on medical co-existing conditions.

The investigators have strategically designed the ENERGY study to lead to an expanded full trial of 2,500 women. If the eventual full trial can document lower breast cancer recurrence risk, it would provide evidence to support weight loss management for breast cancer survivors as a new standard of clinical care.

"The ENERGY Study has great potential to have a major impact on clinical management and outcomes after a diagnosis of breast cancer," Rock said. "If the improvements in psychosocial and medical co-morbidities that we expect to find can be documented in this trial, this finding could itself change the norms of clinical practice and set a new aspect of care for breast cancer survivors after initial treatment."


'/>"/>

Contact: Karen Shea
kshea@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert

Related medicine news :

1. Cymetrix to Provide Extended Business Office Services at UC San Diego Medical Center
2. U.S. HealthWorks in San Diego Region Offering $15 H1N1 Vaccinations for both Walk-Ins and On-Site
3. AIUM gears up for 2010 Annual Convention in San Diego, Calif.
4. AIUM gears up for 2010 Annual Convention in San Diego, California
5. San Diego Hospice and The Institute for Palliative Medicine on the Passing of Sol Price
6. San Diego State University and BIOCOM Institute Receive $4.95 Million Grant: The BRIDGE Project, Linking Education to Employment in San Diegos Life Sciences Industry
7. In San Diego, Hispanics Now Dominate HIV/TB Cases
8. San Diego Unified School District Awarded Silent Hero Grant From got breakfast?(R) Foundation
9. Optelec Gets Creative: CSUN San Diego and VisionZone Premier with Special Movie Debut
10. Palladians Distinguished Clinicians Present at APTAs National CSM Convention in San Diego on Evidenced Informed Management of Chronic Low Back Pain Without Surgery
11. San Diego Cosmetic Dentists Launch New Website and Rejuvenate Online Image
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department ... in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at ... Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... Texas (PRWEB) , ... June 24, 2016 , ... ... International Conference and Scientific Sessions in Dallas that it will receive two significant ... of the grants came as PHA marked its 25th anniversary by recognizing patients, ...
(Date:6/24/2016)... ... 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited to ... Recovery® program to drive cancer patients to and from their cancer treatments. Comfort ... quality of life and ongoing independence. Getting to and from medical treatments is ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... today at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra ... authored journal articles published in Emergency Medicine Practice and Pediatric Emergency ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Research and Markets ... Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic ... Coating, Parenteral) - Global Forecast to 2021" report ... The global pharmaceutical excipients market is projected to ... of 6.1% in the forecast period 2016 to 2021. ...
(Date:6/23/2016)... Capricor Therapeutics, Inc. ... company focused on the discovery, development and commercialization ... in its ongoing randomized HOPE-Duchenne clinical trial (Halt ... its 24-patient target. Capricor expects the trial to ... 2016, and to report top line data from ...
(Date:6/23/2016)... RIDGE, Ill. and INDIANAPOLIS ... of students receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship ... The 2016 scholarship winners, announced today online at ... to let type 1 diabetes stand in the way ... Diabetes has supported the Foundation,s scholarship program since 2012, ...
Breaking Medicine Technology: