Navigation Links
UC San Diego cancer scientist wins $3 million award
Date:2/20/2013

Napoleone Ferrara, MD, PhD, the molecular biologist credited with helping decipher how tumors grow and now senior deputy director for basic sciences at the University of California, San Diego Moores Cancer Center, was today named one of 11 recipients of the inaugural Breakthrough Prize in Life Sciences, which comes with a $3 million cash award.

The prize is the collaborative creation of Mark Zuckerberg, founder of Facebook, and his wife, Priscilla Chan; Sergey Brin, co-founder of Google and his wife, Anne Wojcicki, founder of the genetics company 23andMe; and Yuri Milner, a Russian businessman and philanthropist who established a similar prize in fundamental physics last year, when $3 million each was awarded to nine researchers.

The Breakthrough Prize honors life scientists who have ambitiously pushed the boundaries of their disciplines, taken risks and impacted lives and society.

Ferrara, who is also a distinguished professor of pathology in the UC San Diego School of Medicine's Department of Pathology, was recognized for his work identifying the role of the human VEGF gene in promoting angiogenesis the formation of new blood vessels that can feed tumor growth and subsequent development of two major monoclonal antibody drugs: Bevacizumab (marketed as Avastin), which is used to treat multiple forms of cancer, including breast, brain and colorectal, and ranibizumab (marketed as Lucentis), which treats wet age-related macular degeneration, a leading cause of blindness in the elderly.

"Napoleone's work has profoundly advanced our basic understanding of how cancer develops and grows," said David Brenner, MD, vice chancellor for Health Sciences and dean of the UC San Diego School of Medicine. "More importantly, he helped create brand new drugs and therapies based upon that research to effectively treat a broad range of cancers and other conditions. He continues with those efforts today, pushing himself and colleagues to find better answers to cancer."

Ferrara, 56, came to UC San Diego last year after a long career at Genentech, the San Francisco-based biotechnology company where he did much of his ground-breaking work. He said that when Breakthrough Prize Foundation president Arthur D. Levinson, chairman of Apple and a former Genentech chief executive, called to tell him he had won, he was "very much astonished. I didn't know the award existed."

"The thing I am most proud of," said Ferrara, "is that we've advanced the understanding of basic mechanisms of cancer and we've been able to help people, both in fighting cancer and restoring visual acuity. It's that kind of work that I'm continuing at Moores Cancer Center, where I'll be able to work closely with clinicians and develop new clinical trials."

Scott Lippman, MD, director of the UC San Diego Moores Cancer Center, said the Breakthrough Prize justly recognizes Ferrara's seminal research and how it "has changed therapy for cancer and eye diseases."

"His work epitomizes our overall effort at Moores Cancer Center: high-risk, high-gain, high-impact achievement and innovation in taking basic-science discovery to the clinic and transforming cancer care."

Joining Ferrara among the first winners of the Breakthrough Prize are:

  • Cornelia I. Bargmann, Rockefeller University, who studies the nervous system and human behavior
  • David Botstein, Princeton University, who uses the human genome to map disease biomarkers
  • Lewis C. Cantley, Weill Cornell Medical College, who discovered a family of enzymes related to cell and cancer growth
  • Hans Clevers, Hubrecht Institute in the Netherlands, who has parsed how stem cell processes go awry, resulting in cancer
  • Eric S. Lander, Harvard University and the Massachusetts Institute of Technology (MIT), a leader in the Human Genome Project
  • Titia de Lange, Rockefeller University, who studies the protective tips of chromosomes called telomeres
  • Charles L. Sawyer, Memorial Sloan-Kettering Cancer Center, who has investigated the signals that prompt a cell to become cancerous
  • Bert Vogelstein, Johns Hopkins University, who developed a model for how colon cancer progresses and discovered a protein that suppresses tumor growth
  • Robert A. Weinberg, MIT, who discovered the first human oncogene
  • Shinya Yamanaka, Kyoto University and Gladstone Institutes in San Francisco, for his fundamental research of stem cells

The founders of the Breakthrough Prize intend their awards which will consist of five honorees in subsequent years, each receiving $3 million to boost public attention and awareness of the major players and advances in the life sciences.

There are few limitations on who can win: Anyone can be nominated online at the Breakthrough Prize in Life Sciences Foundation's website. There are no restrictions on age or the number of people who can share the award. The cash prize comes with no constraints on how it can be spent. And individuals can win multiple times. This year's 11 recipients will form a committee to select future winners.


'/>"/>

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert  

Related medicine news :

1. UC San Diego Superfund Research Program receives $15 million grant renewal
2. UC San Diego researchers receive new CIRM funding
3. San Diego Physician to be Recognized at White House for Progress in Health IT
4. Tragic San Diego Dog Attack Leaves One Infant Dead – California Dog Bite Attorneys Revive Pit Bull Warnings
5. UC San Diego, Yale awarded collaborative NSF grant for Neuroscience Gateway
6. Join GSA in San Diego for the Nations Premier Aging Conference!
7. Register now! San Diego meeting will showcase latest aging discoveries
8. Shaft Medical San Diego now offers micro needle sclerotherapy to treat scary “spider” veins.
9. Shaft Medical San Diego Now Offers Viridis Derma KTP Laser to Permanently Remove Unwanted Spider Veins
10. Massage School San Diego Releases Raw Food Holiday Ideas
11. Continuing education provider HomeCEUConnection.com Announces Upcoming Attendance at Annual American Physical Therapy Association Combined Sections Meeting in San Diego.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UC San Diego cancer scientist wins $3 million award
(Date:5/27/2017)... ... 27, 2017 , ... From May 21-23, hearing healthcare professionals gained a competitive ... at the Marriott Syracuse Downtown Hotel in Syracuse, New York. , As EarQ’s ... hearing healthcare providers to help them stay ahead in the industry. At the event, ...
(Date:5/26/2017)... ... May 26, 2017 , ... Leading CEOs from biotech, ... 30th and 31st at The Four Seasons Hotel Boston. , The Boston ... sciences, offering exclusive access to key decision makers who influence deal making and ...
(Date:5/26/2017)... ... May 26, 2017 , ... A new analysis of ... the healthiest seniors are located in the Midwest. With the average cost of healthcare ... people are concerned with both the quality and affordability of where they live. An ...
(Date:5/26/2017)... ... ... After raising nearly $30,000 on Kickstarter , about three-times its original ... discounted crowdfunding price on Indiegogo . , “Along with creating an anti-stress gadget ... a fidget toy to the market that was made of superior quality and wouldn’t ...
(Date:5/26/2017)... ... May 26, 2017 , ... Dr. Alex Rabinovich, a highly-skilled ... a new, informational blog post on insurance options. If a Bay Area patient has ... help save time and money. Visiting an in-network provider for a second opinion can ...
Breaking Medicine News(10 mins):
(Date:5/22/2017)... N.Y. , May 22, 2017  Lilac ... treatment Gene-Eden-VIR/Novirin, announces the launch of a ... English, the results of a clinical study that ... year treatment with Gene-Eden-VIR/Novirin in individuals suffering from ... to note that there are no other treatments ...
(Date:5/15/2017)... , May 15, 2017  Amy Baxter MD, ... industry leader in noninvasive pain relief, was awarded a ... magazine. Baxter was recognized at the MM&M Top ... New York City on May 10, 2017. ... the biopharma industry go "beyond the pill."  ...
(Date:5/10/2017)... May 10, 2017 Hologic, Inc. (Nasdaq: ... for the fiscal second quarter ended April 1, 2017 ... $1.84 increased 666.7% compared to the prior year period ... in a significant gain, while non-GAAP diluted EPS of ... or 3.8% in constant currency terms.  Excluding the effects ...
Breaking Medicine Technology: