Navigation Links
UC Irvine stem cell researchers awarded $1.54 million in state funding
Date:1/30/2014

Irvine, Calif., Jan. 30, 2014 Two UC Irvine research teams will receive $1.54 million to further studies on the fundamental structure and function of stem cells. Their work will aid efforts to treat and cure a range of ailments, from cancer to neurological diseases and injuries.

The California Institute for Regenerative Medicine awarded the two grants today to Lisa Flanagan and Peter Donovan of the Sue & Bill Gross Stem Cell Research Center as part of its basic biology awards program.

CIRM's governing board gave 27 such grants worth $27 million to 11 institutions statewide. The funded projects are considered critical to the institute's mission of investigating the underlying mechanisms of stem cell biology, cellular plasticity and cellular differentiation in order to create a foundation for future translational and clinical advances.

Today's grants bring total CIRM funding at UC Irvine to $98.8 million.

"Innovative basic research like this paves the way to better designs for the use of stem cells," said Sidney Golub, director of the Sue & Bill Gross Stem Cell Research Center. "Even more importantly, it can open up entirely new approaches based on a better understanding of how stem cells function."

In one project, Flanagan and her UC Irvine colleagues will utilize a $1 million grant to study what happens on the surface of early-stage neural stem cells that causes them to develop into either neurons or astrocytes different kinds of brain and spinal cord cells. In the course of this work, the team aims to uncover specific properties of human stem cells used to treat neurological diseases and injuries.

"We expect this knowledge will enhance the benefit of these cells in transplants by enabling more control over what sort of mature cells will be formed from transplanted cells," said Flanagan, an assistant professor of neurology, biomedical engineering and anatomy & neurobiology. "We hope our research will greatly improve the identification, isolation and utility of certain types of human neural stem cells."

In the other project, Donovan and fellow UC Irvine researchers Marian Waterman, Robert Edwards and Michelle Digman will use a $540,000 grant for a new kind of microscopy to capture images of the metabolic states of cells in living tissue in order to identify stem cell populations. Because stem cells can give rise to tumors that are metabolically very different from normal tissue, being able to identify cells that are about to create tumors could be immensely helpful in early cancer diagnosis.

"If these studies are successful, our findings can be employed in clinical settings for better diagnosis of human disease," said Donovan, a professor of biological chemistry and developmental & cell biology.


'/>"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
Source:Eurekalert

Related medicine news :

1. UC Irvine’s ‘Perioperative Surgical Home’ Improves Clinical Outcomes While Reducing Healthcare Costs
2. UC Irvine Health Appoints William C. Wilson, MD, as Director of Critical Care Services
3. UC Irvine Health Appoints William C. Wilson, MD, as Hospital Director of Critical Care Services, Division of the Department of Anesthesiology & Perioperative Care
4. The PAWS Pet Company, Inc. to Acquire MESA Pharmacy of Irvine, CA
5. Luke Bryan Tickets: Luke Bryan Tickets in Mountain View, Sacramento, San Diego, North Little Rock and Irvine Go On Sale to the General Public Friday, June 14th
6. New technology makes breast cancer surgery more precise at UC Irvine
7. iGym Fitness Introduces New Website To Keep Their Irvine Clients Informed About Their Latest Fitness Options
8. Affordable Scrum Trainings In Irvine by Conscires Agile Practices
9. Circadian clock gene rhythms in brain altered in depression, UC Irvine Health study finds
10. Dr. Ahsan Rashid, MD Announces Opening of New Medical Facility in Irvine, California
11. University of California Irvine, Medical Center Selects Jvion as their ICD-10 Risk Assessment and Crosswalk Provider
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2017)... ... June 20, 2017 , ... AMC Health , the leading provider ... the clinical trials market. Similar to its approach in demonstrating positive outcomes in the ... marketplace by proving the value of eVisits to support virtual studies. , ...
(Date:6/20/2017)... ... June 20, 2017 , ... ... in Cincinnati, OH for leading-edge care, whether or not they have a referral. ... the BIOLASE WaterLase® iPlus™ laser, she targets bacteria and damaged tissue without affecting ...
(Date:6/20/2017)... JEFFERSON HILLS, PA (PRWEB) , ... June 20, ... ... now available at Allegheny Health Network’s (AHN) Jefferson Hospital is providing physicians with ... 1.5T, 48-channel scanner provides higher-resolution images than traditional MRIs, enabling doctors to get ...
(Date:6/20/2017)... ... June 20, 2017 , ... ... SweetLeaf® Stevia Sweetener, Michael P. May, Ph.D., recently accepted the distinguished Sun Corridor ... Program selected Wisdom Natural Brands (WNB), and 16 other businesses from Pima, Pinal, ...
(Date:6/20/2017)... ... 20, 2017 , ... BrightStar Care Centerville/South Dayton, a home ... Joint Commission, which accredits and certifies nearly 21,000 healthcare organizations and programs in ... symbol of quality that reflects an organization’s commitment to meeting certain performance standards. ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... 7, 2017  Novavax, Inc., (Nasdaq: NVAX ) ... 2 trials of its RSV F protein recombinant nanoparticle vaccine ... have been published in the journal Vaccine ... in prior scientific conferences). The Company previously announced top ... is developing the RSV F Vaccine with the goal of ...
(Date:6/3/2017)... , June 3, 2017  Eli Lilly ... announced that results from the Phase 3 MONARCH ... (CDK)4 & 6 inhibitor, in combination with fulvestrant, ... with fulvestrant alone in women with hormone-receptor-positive (HR+), ... breast cancer who have relapsed or progressed after ...
(Date:5/30/2017)... May 30, 2017 Hill-Rom Holdings, Inc. (NYSE: HRC), ... Global Healthcare Conference on Tuesday, June 13, 2017, in ... , Hill-Rom,s president and chief executive officer, is scheduled to ... audio webcast can be accessed at http://ir.hill-rom.com/events.cfm . A ... the live event through September 13, 2017. ...
Breaking Medicine Technology: