Navigation Links
UC Davis MIND Institute researchers to present on autism at AAAS Annual Meeting in Vancouver
Date:2/18/2012

Two UC Davis MIND Institute researchers will lead a symposium on relationships between genetic, epigenetic and environmental influences on the development of autism in children during the American Association for the Advancement of Science (AAAS) Annual Meeting, Feb. 16 -18 in Vancouver, Canada.

The symposium, "Autism: Genetic, Epigenetic and Environmental Factors Influencing Neural Networks," will be held Feb. 18. The researchers, both affiliated with the UC Davis MIND Institute, are Isaac Pessah, director of the UC Davis Children's Center for Environmental Health and Disease Prevention and a professor in the UC Davis School of Veterinary Medicine, and Janine LaSalle, professor in the Department of Medical Microbiology and Immunology and in the Rowe Program in Human Genetics.

A news briefing on the symposium will be held at 9 a.m. on Feb. 19 in Room 221 on the second Level of the Vancouver Convention Center.

Autism is a heterogeneous set of developmental disorders with complex etiologies. The goal of the symposium is to present a multidisciplinary perspective on how genetic, epigenetic and environmental factors can interact to promote autism risk. Other presenters will include symposium co-organizer Cindy Lawler of the National Institute of Environmental Health Sciences, Scott Selleck of Pennsylvania State University and Pat Leavitt of the University of Southern California.

Pessah, the symposium organizer, will address how understanding how low-level chemical exposures influence molecular, cellular and behavioral outcomes relevant to the development of autism will enlighten geneticists, neuroscientists and immunologists about autism's complex etiologies, and possibly yield novel intervention strategies. The inherent imbalances in neuronal connectivity in children at risk for autism are likely to provide the biological substrate for enhanced susceptibility to environmental triggers that are known to target signaling systems. He also will discuss how recent results from studies conducted by investigators at the UC Davis Center for Children's Environmental Health highlight examples of gene/environment interactions relevant to autism risk.

LaSalle will discuss her recent research into a particular flame-retardant chemical persistent in the environment, and how genetically engineered autism mice exposed to the substance were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning and long-term memory, when compared with the offspring of normal unexposed mice.

The research is the first to link genetics and epigenetics with exposure to a flame retardant chemical. Other findings of the research are that female offspring of mice exposed to BDE-47 spent half as much time interacting with other mice in a 10-minute sociability test when compared with controls. The reduced sociability in BDE-47 exposed females corresponded to reduced DNA methylation in females, regardless of genotype. In addition, genetic and environmental interaction effects in this study were specifically observed in females.


'/>"/>

Contact: Phyllis K. Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis Health System
Source:Eurekalert

Related medicine news :

1. UC Davis researchers refine nanoparticles for more accurate delivery of cancer drugs
2. Lower risk of death linked with access to key attributes of primary care, UC Davis study shows
3. $6.3 million center at UCSF and UC Davis seeks ways to diagnose and prevent osteoarthritis
4. UC Davis researchers develop computer model for testing heart-disease drugs
5. UC Davis pain research may pave the way to understanding and controlling chronic pain
6. UC Davis surgeons test innovative device in patient with swallowing disorder
7. Inhaled steroids increase diabetes risk, say Lady Davis Institute researchers
8. UC Davis scientists find link between arthritis pain reliever and cardiovascular events
9. UC Davis study finds low liver cancer survival rates among Laotian/Hmong-Americans
10. New UC Davis study finds early Alzheimers identification method
11. DavisPTnetwork Recruits Bloggers to Report Key Session Learning Points Live from APTA 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... NY (PRWEB) , ... January 19, 2017 , ... ... of Clinical Conductor CTMS, which provides a modern CTMS workflow designed to seamlessly ... management information has been condensed to a single page, maximizing usability and improving ...
(Date:1/19/2017)... ... January 19, 2017 , ... Students interested in video can get a jump ... winner will earn a $1,000 scholarship and have his or her video posted on ... deadline is May 31, with the winner announced on June 9. , The competition ...
(Date:1/19/2017)... ... January 19, 2017 , ... Workrite Ergonomics announced this week ... Tranquility privacy panel system was designed to deliver the ideal blend of acoustic ... and provide the visual privacy required to maintain concentration levels and increase productivity. ...
(Date:1/19/2017)... , ... January 19, 2017 , ... Allegheny Health Network ... patients who seek access to the Network’s programs and services in the greater Pittsburgh ... specialty care appointments will be offered one for that same afternoon. , ...
(Date:1/19/2017)... ... January 19, 2017 , ... Rountree Brady Insurance Agency, a ... throughout eastern Georgia, is embarking on a charity effort to raise awareness and ... Americans every year than anything else, yet risk factors associated with heart disease ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... ViewRay, Inc. (Nasdaq: VRAY) announced today that the ... in Germany , has purchased a ... University Clinic Heidelberg as part of its initiative for ... will be headed by Medical Director and Professor Jürgen ... the German Cancer Research Center (DKFZ), the Heidelberg Heavy ...
(Date:1/19/2017)... , January 19, 2017 ... appears serious about reducing the FDA,s regulatory strictness ... in the medical drug industry, many of the ... new clinical trials and development of advanced drug ... ahead with recent developments include:  Moleculin Biotech, Inc., ...
(Date:1/19/2017)... ALAMEDA, Calif. , Jan. 18, 2017 /PRNewswire/ ... (MPI) solutions has entered into an agreement with ... for the Momentum MPI imaging system based on ... VivoQuant will be distributed as a complete MPI ... to enable quantitative nanoparticle or cell imaging in ...
Breaking Medicine Technology: