Navigation Links
UBC researchers to lead $4.7-million study on early-stage oral cancer
Date:5/27/2011

Researchers from the University of British Columbia's Faculties of Medicine, Science and Dentistry are leading a $4.7-million pan-Canadian clinical trial aimed at improving outcomes for patients undergoing surgery for oral squamous cell cancers.

Funded by the Terry Fox Research Institute, the Canadian Optically Guided Approach for Oral Lesions Surgical Trial, or COOLS Study, involves universities and hospitals in nine Canadian cities. Findings from the study could revolutionize clinical practice here and around the world.

According to the Canadian Cancer Society, an estimated 3,400 Canadians are diagnosed with oral cancer every year. In 2010, the estimated number of deaths due to oral cancer was 1,150. Currently, about 30 per cent of patients who receive oral surgery have their cancer recur. The COOLS Study will investigate the effectiveness of a fluorescence visualization, or "blue light," to distinguish between healthy tissues from tumours or pre-cancerous cells in the mouth. Under the blue light, normal tissue generates a fluorescence which is absent in tumour or pre-cancerous tissue.

"In work we've conducted to date in Vancouver, there has been almost no recurrence where surgery followed the contour of the lesion shown by using FV-guided surgery. Working together with surgeons, pathologists, research staff and scientists, this TFRI-funded study will enable us to test the approach on a broader cohort of patients at sites across the country and obtain the evidence required to change current practice." says principal investigator Dr. Catherine Poh, a senior scientist with BC Cancer Agency, an associate professor at the UBC Faculty of Dentistry and a consulting dentist at Vancouver General Hospital.

"Our surgical community has expressed great interest in participating in this trial which provides an unique and important opportunity to assess a surgical intervention in a controlled prospective manner across many sites," says principal investigator Dr. Scott Durham, head of the division of otolaryngology at Vancouver General Hospital and a clinical professor at UBC's Faculty of Medicine. The study aims to build a network of clinicians, pathologists and research staff across the country to fight oral cancer.

"This study will have an immediate impact on practice if the study turns out the way we hope," says principal Investigator Dr. Miriam Rosin, a senior scientist with the BC Cancer Agency who holds joint appointments at UBC and Simon Fraser University. "If the study is successful, it will help to reduce the number of deaths from oral cancer as well as to improve the quality of life for people living with this disease. Working with scientists, we will have this new approach ready to disseminate to the surgical community at large and even globally."

The study's lead investigators also include Calum Macaulay, a clinical associate professor at the UBC Faculty of Medicine and an associate member in Medical Physics in the UBC Faculty of Science; and Stuart Peacock, an associate professor at UBC's School of Population and Public Health in the Faculty of Medicine.


'/>"/>

Contact: Brian Lin
brian.lin@ubc.ca
604-822-2234
University of British Columbia
Source:Eurekalert

Related medicine news :

1. Researchers evaluate red wine compound for treating concussions in pro boxers
2. Researchers Find Cousin of Hepatitis C Virus in Dogs
3. Researchers discover link between obesity gene and breast cancer
4. Mount Sinai researchers discover possible new target for sarcoma treatment and prevention
5. Researchers connect electrical brain disturbances to worse outcomes following neurotrauma
6. Pitt researchers build a better mouse model to study depression
7. Researchers discover that lymphocyte count indicates prognosis of patients with renal cell carcinoma
8. Researchers home in on genetic signature of esophageal cancer
9. Legendary Hollywood directors and renowned researchers awarded 2011 Dan David Prizes
10. Columbia researchers work to prevent blindness from age-related macular degeneration
11. Hebrew University researchers show octopuses make some pretty good moves
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/21/2017)... ... 21, 2017 , ... "ProDOF is the perfect set of tools for video editors that want ... scene," said Christina Austin - CEO of Pixel Film Studios. , Video editors using ... illusion of a DSLR racking focus from one area into the next. ProDOF comes ...
(Date:1/21/2017)... ... January 21, 2017 , ... Northern ... has recently joined their multi-specialty medical group. The dermatology practice provides general ... , “We’re excited to add this excellent dermatology practice to our group’s medical ...
(Date:1/20/2017)... ... ... Launches New ADA Portable Motion Trek BP 300 Lift. Built for durability, this pool lift ... can be wheeled out of the way and stored when not in use. It is ... the feedback from customers into specific enhancements and created a new product that is built ...
(Date:1/20/2017)... Boca Raton, FL (PRWEB) , ... January 20, 2017 , ... ... supplement development, announced it attended the January ECRM trade show to continue the marketing ... technologically advanced vitamin C supplement, known for providing 400 percent better absorption than traditional ...
(Date:1/20/2017)... ... January 20, 2017 , ... International Protein, a company based out ... announced it attended the January ECRM trade show in Hilton Head, SC. , ... was determined to create a line of products that would elevate her fitness regime. ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... YORK , Jan. 19, 2017 ... USD 233.7 billion by 2025, according to a ... market is anticipated to be predominantly driven by ... resulting into the large-scale production of new and ... the influx of drugs at an unprecedented rate ...
(Date:1/19/2017)... -- The Global Therapy Partnering Terms and Agreements since ... and agreements entered into by the world,s leading healthcare ... deals by value - Deals listed by company A-Z, ... report provides understanding and access to the partnering deals ... companies. The report provides an analysis of partnering ...
(Date:1/19/2017)... Conference Call and Webcast to Follow Vanda ... will release results for the fourth quarter of 2016 on Wednesday, ... ... at 4:30 PM ET on Wednesday, February 15, 2017, during which ... results and other corporate activities. To participate in the conference call, ...
Breaking Medicine Technology: