BUFFALO, N.Y. -- Today's major announcement at the American Society of Clinical Oncology annual meeting that the drug exemestane significantly reduces the risk of breast cancer in high-risk, postmenopausal women is the result of an international, randomized double-blind phase III clinical trial in which University at Buffalo researchers and hundreds of Western New York women played a critical role.
The findings will be published online June 4 at 11:30 a.m. EST in the New England Journal of Medicine.
More than 500 Western New York women participated in the study, according to Jean Wactawski-Wende, PhD, principal investigator of the Buffalo ExCel clinical center, co-author of the manuscript and professor and associate chair of the Department of Social and Preventive Medicine in the UB School of Public Health and Health Professions.
In all, 4,560 women participated at sites located throughout the U.S., Canada, France and Spain.
"Our center here in Western New York had the largest enrollment of any site involved in the exemestane study, including those based in major cities much larger than Buffalo," says Wactawski-Wende, also a professor in the Department of Gynecology-Obstetrics in the UB School of Medicine and Biomedical Sciences and UB vice provost for strategic initiatives.
That didn't surprise her. As a researcher on numerous clinical research studies, some of which were part of the landmark Women's Health Initiative, a national study launched in 1993 by the National Institutes of Health to address women's health, Wactawski-Wende has found Western New York women particularly eager to participate.
"We have been so successful here in Western New York in enrolling women in clinical trials," she says. "Western New York women are particularly willing to do their part to advance knowledge and advance science. They do it for their daughters and their granddaughters. They're so altruistic. They want to know more about how to im
|Contact: Ellen Goldbaum|
University at Buffalo