Navigation Links
UAlberta prostate cancer researcher and team developing 'homing beacon drugs' to target cancer cells
Date:11/20/2012

A medical researcher with the University of Alberta and his team just published their findings about their work on developing 'homing beacon drugs' that kill only cancer cells, not healthy ones, thanks to nano-technology.

John Lewis, the Frank and Carla Sojonky Chair in Prostate Cancer Research with the Faculty of Medicine & Dentistry, published his findings in the peer-reviewed journal, Nano Letters. He is also an associate professor in the Department of Oncology, a Fellow with the National Institute for Nanotechnology at the U of A and director of the Translational Prostate Cancer Research Group.

Lewis noted chemotherapy goes through the body and kills any cells that are dividing, even healthy ones which is why cancer patients have immune system problems, hair loss, nausea and skin problems.

"We are developing smart drugs that determine which are the cancer cells and which aren't, then selectively kill only the cancer cells. The drugs look for a protein that is only found in cancer cells, not normal cells. This system acts like a homing beacon for tumours."

These drugs, tested to date in only animal lab models, could be used within a week of cancer diagnoses, predicts Lewis. The drugs would target cancerous cells throughout the body attacking sneaky cancer cells that have already escaped and grown outside the site of the main tumour.

Lewis wasn't sure when these homing beacon drugs could be available for physicians to use with patients, but hopes his works paves the way for patient-centered therapies.

"If we can use 'smart' drugs that home in on tumours, we can dramatically decrease side effects for patients, lower the chance of recurrence, and hopefully increase the cancer survival rate."

Meanwhile, Lewis and his research team are continuing their work on trying to figure out what causes cancer cells to escape and spread from the main tumour site because the cells that move are different than the ones in the main tumour. They have pinpointed numerous genes that set these 'moving' cancer cells apart from the ones that stay put. Based on this research, they have come up with a drug that uses a 'tumour glue' to prevent these moving cancer cells from breaking apart from the main tumour, which prevents the spread of the cancer. Using knowledge gained from the 'tumour glue' drug, Lewis and his team are working to develop new blood tests to predict whether prostate and other cancers will spread.


'/>"/>

Contact: Raquel Maurier
raquel.maurier@ualberta.ca
780-492-5986
University of Alberta Faculty of Medicine & Dentistry
Source:Eurekalert

Related medicine news :

1. Prostate Cancer Websites Often Hard to Understand: Study
2. Mayo Clinic gets FDA approval for new imaging agent for recurrent prostate cancer
3. New targeted therapy for advanced prostate cancer shows anti-tumor activity in clinical trials
4. Active surveillance can reduce suffering among men with prostate cancer
5. Prostate cancer prognosis hope
6. Proton therapy treatment preserves quality of life for men with prostate cancer
7. For many prostate cancer patients, Web sites are too difficult to read
8. Viagra Can Help Prostate Cancer Patients Maintain Sex Lives: Study
9. Drop in testosterone tied to prostate cancer recurrence
10. Moffitt Researchers find genetic predictors of fatigue for some prostate cancer patients
11. First web-based prostate cancer database launches
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... Gastro Health ... to prep patients for colonoscopy at the HyGIeaCare® Center that is to be ... FL. , The HyGIeaCare® Prep, cleared by the U.S. Food and ...
(Date:3/24/2017)... , ... March 24, 2017 , ... ... first Certified Medical Reiki™ Master in Frederick, MD. Judy says, “I am passionate ... during what is often a very difficult and challenging time.” , A Certified ...
(Date:3/24/2017)... ... ... Time GPS”: a dauntless and enlightened study of the second-coming of Christ, and ... published author, Wesley Gerboth, a World War II veteran, with a highly-regarded reputation as ... ninety-one, he shares the Wisdom God bestowed upon him in this publication. , ...
(Date:3/24/2017)... , ... March 24, 2017 , ... ... of inspiring stories about real people of God in congregations across the United ... Miller, a Presbyterian minister ordained in 1964 who has served congregations in seven ...
(Date:3/23/2017)... Greensboro, NC & Seattle, WA (PRWEB) , ... March 23, 2017 ... ... international public health emergency and now estimates that there could be four million Zika-related ... fastest growing epidemics to date with numbers of US cases reported per year skyrocketing ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... Mar. 24, 2017 Research and Markets ... the U.S.: Consumer Strategies" report to their offering. ... Pain ... approach and treat their physical pain, emphasizing consumer survey analysis, ... pain sufferers and adults who have selected illnesses/conditions strongly associated ...
(Date:3/24/2017)... March 24, 2017 ShangPharma, a ... and cost-effective drug development and discovery services, ... biotechnology industry, announced today the intent for ... will be consolidating the Contract Research Organizations ... Shanghai ChemPartner. These entities include ChemPartner Shanghai, ...
(Date:3/24/2017)... Research and Markets has announced the addition of the ... offering. ... is very strong with a total of 97 drug candidates. Pharma giant ... are involved in the development of the IPF therapeutics. The IPF pipeline ... stage, 15 are in Phase II stage, 12 are in Phase I ...
Breaking Medicine Technology: