Navigation Links
UAB joins elite brain cancer research group
Date:7/9/2008

BIRMINGHAM, Ala. Brain cancer experts at the University of Alabama at Birmingham (UAB) have been selected for membership in the Ivy Genomics-Based Medicine Project. The project is a national consortium of cutting-edge hospitals and academic centers working to improve treatment and survival for patients with a kind of malignant brain tumor called a glioma.

As part of the nine-member consortium, UAB will serve as the only research site in the Southeast. UAB is one of four consortium members working in conjunction with its own National Cancer Institute-designated comprehensive cancer center and with a Specialized Program of Research Excellence (SPORE) in brain cancer.

"Being named to this project is a huge honor for us, and it shows we've kept pace and excelled in collaborative and translational research objectives," said G. Yancey Gillespie, Ph.D., UAB professor of neurosurgery and principal investigator for the Ivy Genomics-Based Medicine Project.

Gliomas are tumors that arise by transformation of the body's glial cells, which make up 90 percent of the brain and spinal cord and normally work in concert with neurons. The consortium members strive to unravel how genetic differences between gliomas can lead to more effective and even personalized treatments for patients.

The project will categorize tumors using sophisticated molecular profiling and, for the first time, test each brain tumor against a wide spectrum of treatments to match DNA markers with differences in cancer-fighting response.

"Currently, all patients get basically the same treatment without taking into account the genetic profile of their tumor," said Catherine Ivy, founder of the Ivy Foundation and the driving force behind the genomic project.

"The end goal of this research initiative is to identify how tumors with different genetic features respond to a set of treatment regimens and ultimately, it is hoped, provide physicians with the tools they need to offer brain tumor patients the most effective treatment options," Ivy said.

UAB's membership in the Ivy Genomics-Based Medicine Project is focused on the group's first stage, which has an intensive 18-month research timeline. The nine academic laboratories will use that period to screen dozens of anti-cancer drugs in animal models that help predict tumor-fighting response.

Information from those screenings and other genetic profiling will be linked and analyzed through a secure, real-time computer network. The project's second phase will likely involve human testing of anti-cancer drugs.

Gillespie said the genomic approach has the potential to generate several "firsts" in brain cancer research. "We already are working across disciplines: neuro-oncology, neurosurgery, neuroradiology, neuropathology, pharmacology and biomedical engineering," he said. "This research promises to have a significant impact on the way we treat this disease in the future."


'/>"/>

Contact: Troy Goodman
tdgoodman@uab.edu
205-934-8938
University of Alabama at Birmingham
Source:Eurekalert

Related medicine news :

1. Global Health Progress Joins WHO and DNDi to Call For Increased Commitments to Fighting Neglected Tropical Diseases
2. Dr. Kenneth L. Byrd Joins SteriFx Inc.
3. Leading Vaccine Expert Joins IAVI
4. Marshall Norris Joins NavigatorMD as Director of Business Development and Sales
5. Dr. Howard Epstein Joins Blue Cross as Medical Director for Commercial Operations and Clinical Design
6. Uroplasty Joins the Russell Microcap Index
7. Marc Andreessen Joins Facebook Board of Directors
8. Jerry Steffl Joins Prime Therapeutics as Vice President, Government Affairs
9. Former Assistant US Surgeon General Woodie Kessel, MD, MPH, Joins Academic Network LLC as Senior Scientific Advisor
10. Karen Haney Joins The Turning Point Group as Partner and Vice President of Client Services - Healthcare
11. Bruce Palsulich Joins Relsys International as Chief Innovation & Strategy Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... PawPaws ... a new product that was developed to enhance the health of felines. The formula ... , The two main herbs in the PawPaws Cat Kidney Support Supplement ...
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica Scruggs ... for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs surgery, ... Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, MD, ...
(Date:6/25/2016)... ... ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors in ... School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green Hospital ... at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train in ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
(Date:6/24/2016)... ... 2016 , ... The Pulmonary Hypertension Association (PHA) learned during ... two significant new grants to support its work to advance research and patient ... recognizing patients, medical professionals and scientists for their work in fighting pulmonary hypertension ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...  Collagen Matrix, Inc., ("Collagen Matrix") the driving ... collagen and mineral based medical devices for tissue ... Messer has joined the company as Vice ... growing portfolio of oral surgery, neurosurgery, orthopaedic and ... the Collagen Matrix executive team as an accomplished ...
(Date:6/24/2016)... June 24, 2016   Bay Area Lyme ... Dean Center for Tick Borne Illness , ... Rehabilitation, MIT Hacking Medicine, University of California, Berkeley, ... announced the five finalists of Lyme Innovation ... More than 100 scientists, clinicians, researchers, entrepreneurs, and ...
(Date:6/24/2016)... -- Research and Markets has announced ... Applications, Technologies, Forecasts" report to their offering. ... Smart Skin, Structural Health Monitoring, Composite Smart Structures, ... involves electronic and/or electrical components and circuits that ... such as vehicle bodies or conformally placed upon ...
Breaking Medicine Technology: