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U of Minnesota researcher discovers the starting point of sun-induced skin cancer
Date:5/14/2008

receptors should be relatively protected from the ravages of the light. Working with mouse embryos, the researchers removed the genes for the cannabinoid receptors. They found that the skin of the resulting adult mice, which lacked the receptors, was resistant to the development of UV-induced inflammation and skin tumors called papillomas.

Also, when they exposed cannabinoid receptors to UV light, the receptors changed from an inactive to an active state, indicating they had absorbed and responded to the light.

Why should evolution have produced receptors that respond to both UV light and cannabinoids"

"That we don't know," said Dong.


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Contact: Patty Mattern
mattern@umn.edu
612-624-2801
University of Minnesota
Source:Eurekalert

Page: 1 2

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