Navigation Links
U of M researchers find childhood cancer risk rises with mother's age
Date:7/14/2009

Research from the Masonic Cancer Center, University of Minnesota indicates that a baby born to an older mother may have a slightly increased risk for many of the cancers that occur during childhood.

"Our finding shows that although the absolute risk is low, advancing maternal age may be a factor and explain why, after other factors are adjusted for, some children get cancer," said Logan Spector, Ph.D., assistant professor of pediatrics and cancer epidemiology researcher. Spector and Kimberly Johnson, Ph.D., post doctoral fellow in pediatric epidemiology, led the research team on this study. The results are published in the July 2009 issue of the journal Epidemiology.

Currently, about 1 in 435 children under the age of 15 in the United States gets cancer. Types of cancers most often affecting children include leukemia, lymphoma, central nervous system tumor, neuroblastoma, Wilms' tumor, bone cancer, and soft tissue sarcoma.

For this population-based case-control study, Spector and Johnson used information from birth registry records in New York, Washington, Minnesota, Texas, and California. The study included the records of 17,672 children in those states diagnosed with cancer at ages 0-14 years between 1980 and 2004 and 57,966 children not diagnosed with cancer.

"We saw that the risk of 7 of the 10 most common childhood cancers increased slightly, about 7-10 percent, with every five-year increase in maternal age," Spector said.

The researchers noted the father's age did not seem to matter once the mother's age was taken into account.

Spector and Johnson say more research needs to be done on why the risk for childhood cancer increases with advancing maternal age. Some of the possible explanations could be age-related changes in hormonal levels during pregnancy and alterations in DNA markings in eggs that can be transmitted to the offspring. "A mechanism of inherited mutation is consistent with our finding that the maternal age effect was strongest among children diagnosed with cancer at the earliest age," Spector said.

He anticipates that such research will take on greater importance as more women delay having children until older. Statistics show the percentage of babies born to women 30 years of age or older in the United States has risen from about 18 percent in 1970 to 37 percent in 2005.


'/>"/>

Contact: Sara Martin
buss@umn.edu
612-626-7037
University of Minnesota
Source:Eurekalert

Related medicine news :

1. Researchers map how staph infections alter immune system
2. Researchers identify individuals at risk for developing colon cancer
3. Arizona researchers to sequence West African rice strain
4. Six Researchers to Receive Prestigious Awards from the American Society of Hematology
5. Mount Sinai researchers find new Alzheimers disease treatment promising
6. Researchers consider herd movements to help eradicate bovine TB
7. Pre-cessation patch doubles quit success rate: Researchers call for labeling changes
8. Researchers identify potential patient safety risks among methadone maintenance treatment patients
9. Purdue researchers create prostate cancer homing device for drug delivery
10. Moles and melanoma -- researchers find genetic links to skin cancer
11. Australian researchers identify genes that cause melanoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Viejo, California (PRWEB) , ... June 25, 2016 , ... ... to fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... fully customizable and all within Final Cut Pro X . Simply select a ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary ... Work award to iHire in recognition of their exemplary accomplishments in worksite health promotion. ... Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort ... holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain ... Disease (SCD) is a disorder of the red blood cells, which can cause episodes ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The ... published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... ITASCA, Ill. , June 23, 2016  In a startling ... states are failing their residents by lacking a comprehensive, proven plan ... , a definitive ranking of how states are tackling the ... rating to only four states – Kentucky , ... and Vermont . Of the 28 failing states, ...
(Date:6/23/2016)... June 23, 2016 Bracket , a leading ... next generation clinical outcomes platform, Bracket eCOA (SM) 6.0, ... June 26 – 30, 2016 in Philadelphia ... Clinical Outcome Assessment product of its kind to fully integrate ... Bracket eCOA 6.0 is a flexible platform for electronic ...
(Date:6/23/2016)... -- Guerbet announced today that it has been named a ... One of 12 suppliers to receive the ... of Premier members through exceptional local customer service and ... lower costs. "We ... customer service from Premier," says Massimo Carrara , ...
Breaking Medicine Technology: