Navigation Links
U of M researchers discover fast-acting cyanide antidote
Date:12/26/2007

MINNEAPOLIS / ST. PAUL (December 26, 2007) University of Minnesota Center for Drug Design and Minneapolis VA Medical Center researchers have discovered a new fast-acting antidote to cyanide poisoning. The antidote has potential to save lives of those who are exposed to the chemical namely firefighters, industrial workers, and victims of terrorist attacks.

Current cyanide antidotes work slowly and are ineffective when administered after a certain point, said Steven Patterson, Ph.D., principal investigator and associate director of the University of the Minnesota Center for Drug Design.

Patterson is developing an antidote that was discovered by retired University of Minnesota Professor Herbert Nagasawa. This antidote works in less than three minutes meeting the United States Department of Defense three minute solution standard. The research will be featured in the Dec. 27, 2007 issue of the Journal of Medicinal Chemistry.

Its much, much faster than current antidotes, Patterson said. The antidote is also effective over a wider time window. Giving emergency responders more time is important because its not likely that someone will be exposed to cyanide near a paramedic.

The antidote was tested on animals and has been exceptionally effective, Patterson said. Researchers hope to begin human clinical trials during the next three years.

The antidote is also unique because it can be taken orally (current antidotes must be given intravenously) and may be administered up to an hour prior to cyanide exposure.

Cyanide is a rapid acting toxin that inhibits cellular respiration it prevents the body from using oxygen. This means it rapidly shuts down many of the fundamental biochemical processes the body needs to survive. Symptoms of acute cyanide poisoning include headache, vertigo, lack of motor coordination, weak pulse, abnormal heartbeat, vomiting, stupor, convulsions, coma, and even death.

When released in an enclosed area, cyanide can
'/>"/>

Contact: Nick Hanson
hans2853@umn.edu
612-624-2449
University of Minnesota
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2008)... secondary life insurance market ranked 156 among ...merica on Inc. 500 list, BETHESDA, Md., Aug. 20 /...in the secondary life insurance market, announced ...ing insurance related company in the US by,Inc. ma...8 Inc. 500 list of,fastest growing companies in Am...
(Date:8/20/2008)...esidents Gain Access to High Quality Care as State...g. 20 /PRNewswire-USNewswire/ -- Patients who suff...splant will no longer have to,seek that highly spe...p,care outside the borough of the Bronx. Area pati...gh-quality care locally, without having to travel,...
(Date:8/20/2008)...PRINGS, Pa., Aug. 20 /PRNewswire-USNewswire/ -- Go... agricultural industry is struggling,with high fue...ng the need,to secure the state,s energy independe...g adults., Nearly 900 guests gathered to hear the...ay Luncheon at Ag Progress Days, Pennsylvania,s,la...
(Date:8/20/2008)...n of brown globules helps burn calories, hints of ..., Aug. 20 (HealthDay News) -- A protein that induc...good" brown fat that helps burn calories and plays...he Joslin Diabetes Center in Boston. , They sai...ay help lead to new ways to prevent and treat obes...
Breaking Medicine News(10 mins):Health News:Integrity Capital Partners Ranked 2nd Fastest Growing Insurance Related Company in US by Inc. Magazine 2Health News:Liver Transplant Program Established At Montefiore 2Health News:Liver Transplant Program Established At Montefiore 3Health News:Liver Transplant Program Established At Montefiore 4Health News:Pennsylvania Governor Rendell Highlights Renewable Energy, Health Care Reform at Ag Progress Days 2Health News:Bone Growth Protein Also Promotes 'Good' Fat 2
...the Université de Montréal and the Centre hospital...ced an important breakthrough in fighting the// hu...me, scientists have identified a defect in the imm...he flaw. Dr. Rafick-Pierre Sékaly, an eminent rese...
...Medical Sciences (AIIMS) was Friday asked by a cit...untimely demise of a woman suffering// from heart ...sal Commission held the country's most prestigious...ble for gross negligence. The court asked AIIMS t...
...leaders approved the proposed discount drug plan, ...dications and 60% on generic ones for the// low-in...l require the prescription drug companies to enabl...uired to adhere to this by August 2010, failing wh...
...rdered administrations of all 30 districts to coll...the next three days.// The officials were Thursda...hubaneswar, said a senior health department offici...nt to a laboratory in Pune, Maharashtra, as the st...
Other Medicine News:Health News:Researchers Make a Major Strategic Breakthrough in Controlling the AIDS Virus 2
(Date:8/14/2008)... development to begin in late 2008 or in early 200...tCall/ -- Nuvelo, Inc.,(Nasdaq: NUVO ) today anno...concept trial of NU172, demonstrating that the dir...ined anticoagulation with a rapid,return toward ba...afety,profile., "NU172 has the potential to addre...
(Date:8/13/2008)... Fat Intake Improves Insulin Sensitivity and Reduc...ine Responsiveness, PHOENIX, Aug. 13 /PRNewswire-...Kronos Longevity Research Institute (KLRI) found t...nsitivity and reduces inflammatory,markers, but do...was,recently published in Hormones and Metabolic R...
(Date:8/13/2008)...CRP with ISIS 353512 could provide therapeutic ben...mmatory diseases, CARLSBAD, Calif., Aug. 13 /PRNe...asdaq: ISIS ) announced today it has initiated a,...at inhibits the,production of C-reactive protein (...ts with a variety of diseases including cardiovasc...
(Date:8/12/2008)...alif., Aug. 12 /- DURECT Co...e US Food and Drug Administration,(FDA) has accept... granted,Priority Review. The FDA typically grants...potential to demonstrate significant improvements,...mpleting review of a drug,with Priority Review sta...
Breaking Medicine Technology:Nuvelo Announces Positive Phase 1b Proof-of-Concept Data With Anticoagulant NU172 2Nuvelo Announces Positive Phase 1b Proof-of-Concept Data With Anticoagulant NU172 3Nuvelo Announces Positive Phase 1b Proof-of-Concept Data With Anticoagulant NU172 4Study Shows Benefits of a High Omega-3 Diet in Older Adults 2Study Shows Benefits of a High Omega-3 Diet in Older Adults 3Isis Initiates Clinical Trial of CRP Drug 2Isis Initiates Clinical Trial of CRP Drug 3REMOXY(R) NDA Filing Accepted by FDA and Priority Review Granted 2REMOXY(R) NDA Filing Accepted by FDA and Priority Review Granted 3Capital BlueCross Receives Prestigious Brand Excellence Award From The Blue Cross 26 Blue Shield Association 14353 1Capital BlueCross Receives Prestigious Brand Excellence Award From The Blue Cross 26 Blue Shield Association 14353 2Angiotech showcases its Hemostream 28TM 29 Dialysis Catheter at the Society of Interventional Radiology 28SIR 29 Annual Meeting 3952 1Angiotech showcases its Hemostream 28TM 29 Dialysis Catheter at the Society of Interventional Radiology 28SIR 29 Annual Meeting 3952 2Angiotech showcases its Hemostream 28TM 29 Dialysis Catheter at the Society of Interventional Radiology 28SIR 29 Annual Meeting 3952 3Angiotech showcases its Hemostream 28TM 29 Dialysis Catheter at the Society of Interventional Radiology 28SIR 29 Annual Meeting 3952 4Angiotech showcases its Hemostream 28TM 29 Dialysis Catheter at the Society of Interventional Radiology 28SIR 29 Annual Meeting 3952 5Dialysis Corporation of America Reports Fourth Quarter and Year Ended December 31 2007 Results 14347 1Dialysis Corporation of America Reports Fourth Quarter and Year Ended December 31 2007 Results 14347 2Dialysis Corporation of America Reports Fourth Quarter and Year Ended December 31 2007 Results 14347 3Dialysis Corporation of America Reports Fourth Quarter and Year Ended December 31 2007 Results 14347 4Dialysis Corporation of America Reports Fourth Quarter and Year Ended December 31 2007 Results 14347 5Dialysis Corporation of America Reports Fourth Quarter and Year Ended December 31 2007 Results 14347 6Dialysis Corporation of America Reports Fourth Quarter and Year Ended December 31 2007 Results 14347 7Trubion Pharmaceuticals Inc Reports Fourth Quarter and Year Ended 2007 Financial Results and Provides 2008 Financial Outlook 3950 1Trubion Pharmaceuticals Inc Reports Fourth Quarter and Year Ended 2007 Financial Results and Provides 2008 Financial Outlook 3950 2Trubion Pharmaceuticals Inc Reports Fourth Quarter and Year Ended 2007 Financial Results and Provides 2008 Financial Outlook 3950 3Trubion Pharmaceuticals Inc Reports Fourth Quarter and Year Ended 2007 Financial Results and Provides 2008 Financial Outlook 3950 4Trubion Pharmaceuticals Inc Reports Fourth Quarter and Year Ended 2007 Financial Results and Provides 2008 Financial Outlook 3950 5Trubion Pharmaceuticals Inc Reports Fourth Quarter and Year Ended 2007 Financial Results and Provides 2008 Financial Outlook 3950 6
...ALEIGH, N.C., April 18, 2007 /PRNewswire/ -- Micel...ll be presenting,data on use of its supercritical ...ug-eluting stents at the upcoming Society for,Biom...Chicago,Illinois. , The abstracts describe use of... e-RESS technology to create drug-eluting stents,c...
...ta Reported at American Association for Cancer Res...RNewswire-FirstCall/ -- Favrille,Inc. , a biophar...tive immunotherapies for the treatment of cancer, ...d activity from insect-cell,derived idiotype (Id) ...immunotherapy product candidate FavId(R) for B-cel...
Other Medicine Technology:Micell Technologies Presents Data on Novel Drug-Eluting Stents 2Micell Technologies Presents Data on Novel Drug-Eluting Stents 3Favrille Announces Results From Study Showing Enhanced Activity,From Insect Cell-Derived Immunotherapy for Lymphoma 2Favrille Announces Results From Study Showing Enhanced Activity,From Insect Cell-Derived Immunotherapy for Lymphoma 3Favrille Announces Results From Study Showing Enhanced Activity,From Insect Cell-Derived Immunotherapy for Lymphoma 4
Unit System Slide Cabinet is constructed from hardwood for long lasting.
Shandon Slide File Storage System
Shandon Microscope Slide Trays
... luminance white LED (Light Emitting Diode) light ..., to give you the freedom of using a slit lamp any...t 1.5 lbs. (0.68 kg) with its battery and fits eas...portable design and convenient carrying case make ...
Medicine Products: