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U of M Masonic Cancer Center receives $26 million to lead national BMT cancer research
Date:9/21/2010

Two of the University of Minnesota Masonic Cancer Center's leading physician-scientists on research and treatment of cancers of the blood and bone marrow Philip McGlave, M.D., and Jeffrey Miller, M.D., -- have received renewed five-year program project research grants totaling almost $26 million from the National Cancer Institute (NCI).

McGlave and Miller will use the grants to lead research teams focused on increasing the availability, safety, and effectiveness of hematopoietic stem cell transplantation and cell therapies to improve treatment and survival for the thousand of patients diagnosed annually with leukemia, lymphoma, multiple myeloma and other blood and bone marrow disorders.

About the physician-scientists, their research goals

McGlave, deputy director of the Masonic Cancer Center and director of the University Medical School's Division of Hematology, Oncology, and Transplantation, received more than $12.6 million of renewed funding. He has received NCI funding to lead his stem cell research program for the past 15 years. The renewed funding will allow him to continue years 16-20 of his team's research, focusing on improving stem cell transplant and cell-based treatments.

Miller is associate director of the Masonic Cancer Center's Experimental Therapeutics Program and professor of medicine focusing on hematology, oncology, and transplantation. His award of more than $13.3 million will fund years 6-10 of his team's research on characterizing "natural killer cell" or "NK cells" to reduce the rate of relapse after transplant by leukemia patients. Currently, leukemia returns in about 25 percent of patients who undergo stem cell transplants.

In addition to University of Minnesota researchers, their respective research teams will include blood and marrow stem cell experts at the National Institutes of Health and at more than a dozen cancer research centers across the United States.

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Contact: Nick Hanson
hans2853@umn.edu
612-624-2449
University of Minnesota
Source:Eurekalert

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