Navigation Links
U of Alberta researchers hoping to stop heart disease in cancer patients before it starts
Date:6/2/2011

Researchers in the Faculty of Medicine & Dentistry are trying to reverse a devastating trend: cancer survivors developing cardiovascular disease, one of the top two killers in Canada.

Ian Paterson, an assistant professor of cardiology at the University of Alberta and Edie Pituskin, a registered nurse and PhD candidate in the Faculty of Rehabilitation Medicine, are starting what is called the MANTICORE clinical trials. Women with breast cancer will be put on heart medication before their cancer treatment.

"Our goal is to look at patients diagnosed with cancer and to detect heart disease and risk factors for heart disease sooner then they're being recognized and treat them aggressively," said Paterson. "We're hoping we can prevent heart disease not only during cancer treatment itself but after the cancer treatment is done."

All patients enrolled in this study must start on the heart disease medication with Paterson and Pituskin prior to treatment.

Paterson and Pituskin decided to start with breast cancer patients because it is the leading cancer in women and the leading cause of cancer deaths in women. Treatments have improved drastically over the years, in particular one pharmaceutical called Herceptin.

"The drug has been shown to really improve survival rates of some types of breast cancer," said Paterson. "Unfortunately it can also damage the heart in up to 20 per cent of women taking this drug.

"We're trying to detect signs of injury much more quickly using special blood tests and special imaging tests like an eco-cardiogram and MRI."

The pair will also try to detect if any of the women involved in the study have cardiac risk factors like high blood pressure and they'll try to treat those very aggressively.

MANTICORE looks to enrol 139 patients, so far 15 are involved in Edmonton and the study is now adding centres in Winnipeg and Toronto. The study is being funded by the Alberta Cancer Foundation and Canadian Institutes of Health Research.

Cardio-oncology is an emerging field of medicine and Paterson and Pituskin are leading the way.

"We're one of the first and we could serve as a blue print for other programs," said Paterson, who also added they want to get a number of sites nationally on board with the trials. "Then we'll be able to track outcomes for these patients and develop a registry where we can track how people are doing and have these clinics make a difference."


'/>"/>

Contact: Quinn Phillips
quinn.phillips@ualberta.ca
780-248-2048
University of Alberta Faculty of Medicine & Dentistry
Source:Eurekalert

Related medicine news :

1. Most common cancers in the world decreasing in Alberta: Study
2. Gender-bending fish on the rise in southern Alberta
3. Warning labels better than a fat tax, University of Alberta study shows
4. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
5. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
6. Researchers discover new way to kill pediatric brain tumors
7. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
8. Researchers create drug to keep tumor growth switched off
9. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
10. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
11. Clemson researchers develop hands-free texting application
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their ... Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. , ... Pro X users can now reveal the media of their split screens with ...
(Date:6/26/2016)... ... ... Quality metrics are proliferating in cancer care, and are derived from many ... the beholder, according to experts who offered insights and commentary in the current issue ... the full issue, click here . , For the American Society of Clinical ...
(Date:6/26/2016)... ... June 26, 2016 , ... ... have been diagnosed with endometriosis. These women need a treatment plan to not ... comprehensive approach that can help for preservation of fertility and ultimately achieving a ...
(Date:6/25/2016)... ... 25, 2016 , ... First Choice Emergency Room , the largest network ... the Medical Director of its new Mesquite-Samuell Farm facility. , “We are pleased ... location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. ...
(Date:6/24/2016)... ... 2016 , ... A recent article published June 14 on E ... goes on to state that individuals are now more comfortable seeking to undergo not ... as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  Guerbet announced today that ... Supplier Horizon Award . One of ... was recognized for its support of Premier members through ... clinical excellence, and commitment to lower costs. ... this recognition of our outstanding customer service from Premier," ...
(Date:6/23/2016)... 2016 Research and Markets has ... Global Analysis (United States, China, Japan, Brazil, United Kingdom, ... their offering. Surgical ... business planners, provides surgical procedure volume data in a ... an in-depth analysis of growth drivers and inhibitors, including ...
(Date:6/23/2016)... , June 23, 2016 The ... it continues to present great opportunities to investors. Stock-Callers.com ... today: Intrexon Corp. (NYSE: XON ), Vertex ... Inc. (NASDAQ: ARNA ), and Regeneron Pharmaceuticals ... these stocks and receive your complimentary trade alerts at: ...
Breaking Medicine Technology: