Navigation Links
U.S. Scientists Map Genome of Advanced Prostate Cancer
Date:9/27/2011

TUESDAY, Sept. 27 (HealthDay News) -- A number of recurrent genetic errors common to advanced lethal prostate cancers have been identified by scientists who conducted the first complete genome mapping of these types of cancers.

The team also identified several instances of genetic "hypermutation," an excess of single-letter DNA errors that can give the cancers resistance to therapies commonly used to slow advanced prostate cancer, such as surgical castration and androgen-blocking drugs.

The study by researchers at the Fred Hutchinson Cancer Research Center and the University of Washington in Seattle was published in this week's online edition of the Proceedings of the National Academy of Sciences.

"The most interesting finding to come out of our DNA sequencing project was the discovery of three aggressive tumor types that had 10 times the number of mutations compared to the other advanced prostate cancers we studied," co-corresponding author Dr. Peter S. Nelson said in a research center news release.

"That was very surprising and unusual. We don't know the cause of these hypermutated tumors, but the frequency of the mutations suggests these tumors might evolve very rapidly to develop resistance to therapies," he added.

The discovery of these genetic mutations could help improve understanding of why some prostate cancers are so deadly, and could also lead to improved screening tests or treatments, Nelson suggested.

More information

The American Cancer Society has more about prostate cancer.

-- Robert Preidt

SOURCE: Fred Hutchinson Cancer Research Center, news release, Sept. 26, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Scientists ID More Genes Linked to Heart Disease
2. UCLA scientists find H1N1 flu virus prevalent in animals in Africa
3. Scientists Reconstruct the Movies in Our Minds
4. Scientists Discover Key Gene Mutation Behind Lou Gehrigs Disease
5. Scientists identify a key molecule that blocks abnormal blood vessel growth in tumors
6. NIH scientists find earliest known evidence of 1918 influenza pandemic
7. A*STAR scientists make headway for cancer treatment and cancer prevention with landmark discovery
8. To treat rare disease, NIH scientists repurpose FDA-approved drug
9. UT MD Anderson scientists discover secret life of chromatin
10. Scientists Use Stem Cells for Blood Self-Transfusion
11. Scripps Research scientists reveal how white blood cell promotes growth and spread of cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
U.S. Scientists Map Genome of Advanced Prostate Cancer
(Date:12/20/2014)... 20, 2014 Today, Balfleet.com, one of ... Christmas Sale, offering 50%-70% off on its Mother ... , The mother of the bride dresses from Balfleet.com ... is 24/7 accessible and takes pride in providing high ... “We are offering great discounts on our mother of ...
(Date:12/19/2014)... It’s very easy to become overwhelmed with the holidays ... the wayside until Christmas and the New Year are over. ... that burning desire to just escape it all and get ... Telluride with a no-fuss, affordable package. Montrose Days Inn will ... and ensure that all accommodations are met. Plus, everyone has ...
(Date:12/19/2014)... Florida (PRWEB) December 19, 2014 Sub Zero ... to sponsor a blood drive Sunday the 28th from 2pm-6pm ... Road & Sawyer Road in Sarasota, FL. , Inquiries regarding ... thank you for participating in the donating process, Sub Zero ... free flash frozen, custom ice cream. , About Sub Zero ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 ... dedicated to developing educational events, tools and resources ... Rouxbe Cooking School , the world’s leading online ... prescription every human being needs: Culinary Rx. As ... cooking course, Culinary Rx, scheduled for debut spring ...
(Date:12/19/2014)... Santa Rosa, CA (PRWEB) December 19, 2014 ... 2x4 and 5x5 SuperClone Rooms. SuperCloset continues to offer ... grow solutions. Pair one of the new SuperClone Rooms ... truly professional, perpetual, and turnkey indoor hydroponic grow room ... cloner in the world, SuperCloset’s SuperPonic SuperCloner 50 ...
Breaking Medicine News(10 mins):Health News:Balfleet.com is Offering 50%-70% Off of its Mother of the Bride Dresses 2Health News:Days Inn Montrose Colorado Delivers Last Minute Holiday Season Ski Getaway Accommodations 2Health News:Shark Tank’s Sub Zero Ice Cream Sponsors Blood Drive 2Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 2Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 3Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 4Health News:SuperCloset Continues to Innovate with New Complete Indoor Grow Room Packages, The SuperClone Rooms are the Newest Addition to the Award Winning SuperRoom Lineup 2
... Massachusetts General Hospital (MGH), together with a coalition of ... world,s largest registry of patients who have had optical ... an intravascular imaging technology that researchers hope will give ... plaques that cause heart attacks and sudden cardiac death. ...
... finds , THURSDAY, March 25 (HealthDay News) -- More than ... said that they drank alcohol in the past month, according ... The analysis of 2006-2008 data from the National Survey on ... rates were as high as 40 percent in some states, ...
... The effectiveness of ordinary surgical masks as opposed to ... H1N1 influenza virus has been the subject of debate. ... issue of Clinical Infectious Diseases, available online ... as effective as respirators in this regard. ...
... ... strategy to treat motor symptoms in rats with a disease designed to mimic Parkinson,s disease. ... San Francisco, CA (Vocus) ... symptoms in rats with a disease designed to mimic Parkinson,s disease., , , , ,The ...
... This press release is available in French . ... a previously hidden channel to attack leukemia and other cancer ... Journal of Biological Chemistry . The findings from the Universit ... way doctors treat cancer patients. "We found a gateway, ...
... survey finds , THURSDAY, March 25 (HealthDay News) ... likely to be chronically offline: they use the Internet ... , The survey, conducted by the Pew Internet & ... published online March 24, found that just 62 percent ...
Cached Medicine News:Health News:Mass. General Hospital to create registry for coronary optical coherence tomography 2Health News:Underage Drinking Soars in U.S. 2Health News:Novel Parkinson's Treatment Strategy Involves Cell Transplantation 2Health News:Novel Parkinson's Treatment Strategy Involves Cell Transplantation 3Health News:Novel Parkinson's Treatment Strategy Involves Cell Transplantation 4Health News:New gateway to treat leukemia and other cancers 2Health News:Chronic Disease Linked to Less Internet Usage 2
(Date:12/19/2014)... 19, 2014  Newport Corporation (NASDAQ: ... has joined the company,s Board of Directors.  Dr. ... a director of Evans Analytical Group, a leading ... analytical services to companies in a wide range ... Evans Analytical Group, Dr. Kadia spent nine years ...
(Date:12/19/2014)... 2014 Breckenridge Pharmaceutical, Inc. announced today that ... Laboratories Pvt. Ltd. ( Hyderabad, India ) ... new ANDAs.  Under the terms of the agreement, MSN ... Breckenridge for the U.S. market, and Breckenridge will market ... MSN have agreed to develop an oral antibiotic with ...
(Date:12/19/2014)... , Dec. 19, 2014 In ... research and marketing communication tools are essential for ... competitive – consequently consumers, desires, preferences, and unmet ... environment, market research groups across all industries are ... communication tools. However, the adoption of new market ...
Breaking Medicine Technology:Siddhartha Kadia, Ph.D. Joins Board of Directors of Newport Corporation 2Breckenridge Pharmaceutical signs Multi-Product Generic Agreement with MSN Laboratories Pvt. Ltd. 2Study Uncovers New Tools and Techniques for Understanding Consumer Decision Making 2
... SKILLMAN, N.J., Feb. 7, 2011 ConvaTec, a world-leading ... and hospital care, today announced the appointment of several ... Nino Pionati has been appointed President, Intercontinental in ... Latin America and Canada. These markets continue to be ...
... 2011 BioSpecifics Technologies Corp. (Nasdaq: BSTC ... first in class collagenase-based products, today announced that its ... "Rights Agreement"), adopted May 14, 2002 and previously amended ... increases the ownership threshold for determining "Acquiring Person" status ...
Cached Medicine Technology:ConvaTec Announces New Appointments to Leadership Team 2
... NGAL (neutrophil gelatinase-associated lipocalin, lipocalin-2) is a ... predicting acute renal failure with a >90% ... especially in urine, as early as 2 ... an ideal diagnostic marker for acute renal ...
... quality control material used for monitoring the ... on CO-Oximeter instrumentation. It provides an alternative ... the human physiologic range for tHb, O2Hb, ... three (3) levels for monitoring analyzer performance ...
... 233 is an assayed quality ... the measurements of total hemoglobin ... instrumentation. It is available in ... analyzer performance at varying points ...
... QC 623 is an assayed quality control material ... available in four (4) levels for monitoring analyzer ... It may be used on multiple test analyzers ... the Radiometer 600). QC623 is also for use ...
Medicine Products: