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U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines
Date:12/16/2009

usly been studied, then that's good evidence that the embryonic stem cell line was derived from donors belonging to that population, or a closely related population," Rosenberg said.

Mosher noted that the U-M Life Sciences Institute was created to bring together researchers with different sets of expertise to collaborate on problems they couldn't solve individually.

"This is a perfect example of that type of cross-disciplinary collaboration," said Mosher, an assistant research scientist at LSI. "By combining two seemingly disparate scientific approaches, we were able to make a discovery that adds important new insights."

In addition to Mosher, Morrison and Rosenberg, the paper's authors are Trevor Pemberton, Kristina Harter, Chaolong Wang and Erkan Buzbas of the University of Michigan, Petr Dvorak of Masaryk University in the Czech Republic, and Carlos Simon of Valencia University in Spain.

The study was funded by the Alfred P. Sloan Foundation and donors to the U-M Center for Stem Cell Biology, especially the Jeffrey and Susan Liss Fund for the Life Sciences.

Related links:

Read the New England Journal of Medicine article: http://content.nejm.org/cgi/content/full/NEJMc0910371

University of Michigan stem cell research site: http://umich.edu/stemcell

U-M Center for Stem Cell Biology:

SOURCE University of Michigan Health System
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