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U. Iowa study suggests antidepressants aid physical recovery in stroke
Date:4/7/2011

global measure of overall physical and motor disability called the Rankin Scale, the UI researchers showed that antidepressants significantly reduced physical disability over the one-year period compared to placebo. The Rankin Scale categorizes disability on a six-point scale, with zero being no disability.

Patients who got placebo did have initial recovery for several months, but then the recovery leveled off compared to patients who received the antidepressants and continued to improve steadily over the year of the study.

"Based on our study we saw an improvement of 1 to 1.5 categories on the Rankin Scale. Patients were moving from having such severe physical disability that they required help in daily activities to a situation where they still had some symptoms but, on average, could take care of their own daily activities," Robinson said.

Robinson acknowledged that the study's relatively small size and similarities among the patient population represented limitations. The team aims to validate the importance of their findings by testing the effect of antidepressants on physical recovery from stroke in a much larger and more diverse group of patients.


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Contact: Jennifer Brown
jennifer-l-brown@uiowa.edu
319-356-7124
University of Iowa Health Care
Source:Eurekalert

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