Navigation Links
Tysabri May Cause Liver Damage, Health Officials Say
Date:2/27/2008

MS drug also used to treat Crohn's disease can show injury in as little as 6 days

WEDNESDAY, Feb. 27 (HealthDay News) -- The controversial multiple sclerosis drug Tysabri can start causing liver damage within six days of the first dose, U.S. health officials said Wednesday.

In January, the U.S. Food and Drug Administration expanded the use of Tysabri to treat Crohn's disease, a chronic inflammation of the digestive tract.

The drug has also been linked with serious brain infections in multiple sclerosis patients, as well as liver damage.

When the FDA granted approval to use Tysabri for Crohn's disease, it asked the manufacturers -- Biogen Idec of Cambridge, Mass., and Elan Corp. -- to send letters to health-care providers about the potential problems with liver toxicity.

"This [the Biogen Idec letter] was part of the approval of Jan. 14," said FDA spokeswoman Rita Chappelle. "The manufacturer was going to send out a notice to health-care providers to make them aware of the potential problem."

A warning about the danger of Tysabri to the liver is already on the product label.

"FDA does not require 'Dear Doctor Letters,' but can request that a sponsor send one to inform health-care practitioners about new adverse events that are labeled," Chappelle added.

According to the letter from Biogen Idec, the drug should be stopped or discontinued if patients become jaundiced or have other evidence of liver damage.

Tysabri (natalizumab), a monoclonal antibody used to treat MS, has been under a cloud of controversy for some time. The drug works by attaching itself to white blood cells called lymphocytes and preventing them from entering the brain, where they do damage that causes the disabling symptoms of MS.

But the drug has a checkered past. It first received FDA approval in November 2004, only to be pulled from the market three months later, after several patients
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Stopping Tysabri May Worsen MS
2. MS Drug Tysabri Approved for Crohns Disease
3. Drug for cluster headaches may cause heart problems
4. Study Points to Cause of Vioxx Heart Risk
5. Damp, Moldy Homes May Cause Depression
6. Constipations Many Causes and Cures
7. High Co-Pays Cause Seniors to Go Without Meds
8. 13 percent of women stop taking breast cancer drug because of side effects, U-M study finds
9. Vocal cord dysfunction may be caused by work
10. Study finds drug spending caps cause some seniors to quit taking key medicines
11. Medicare Spending Caps Cause Seniors to Stop Meds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tysabri May Cause Liver Damage, Health Officials Say
(Date:1/22/2015)... Deer Path of Huntley -- a ... Happy Hour from 3 p.m. to 4 p.m. on Feb. 13. ... Huntley, Illinois, serves adults with physical disabilities between the ages of ... Day treats, games and sweetheart-themed karaoke. , For more information about ...
(Date:1/22/2015)... January 22, 2015 Woodloch Pines, an ... been selected by TripAdvisor as the number one best large ... best in the world for their annual Travelers’ Choice Awards. ... community . The website is home to millions of unbiased ...
(Date:1/22/2015)... 23, 2015 Angelweddingdress is a famous wedding ... its customers to follow it on Facebook, Twitter, and Pinterest. ... Day gift. Angelweddingdress draws a lottery every week. , Moreover, ... Feb. 28, 2015. Click Angelweddingdress homepage for more ...
(Date:1/22/2015)... TX (PRWEB) January 22, 2015 A ... issue of experience and person-centeredness in the long-term care ... towards action across the continuum. The paper, “The Power ... Continuum,” engages perspectives and practices of the patient, resident ...
(Date:1/22/2015)... Joan Lunden, award-winning American journalist, beloved television host, ... 32nd Annual Miami Breast Cancer Conference planned and ... , shares that “a fast-growing, virulent” cancer in her ... not followed up her clean mammogram with an ultrasound. ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6
... generic drug names. Unregulated continuing medical education ... of the strategies used by some in the ... doctors, according to a Georgetown University Medical Center ... at increasing physician access to unbiased information about ...
... Veteran Will Focus on Broader Product Distribution, Revenue ... DecisionView, Inc., the leading provider of Clinical Optimization ... that its Board of Directors has appointed James ... and CEO of DecisionView, effective immediately. Most recently, ...
... Nearly 60% of Americans Age 40 to 79 ... Loss, Divorce, Death of a Spouse or Major ... Affected Both Financially and EmotionallyAARP Financial Inc. President ... to Successfully Managing Your Finances in a Life ...
... 31 Conseco, Inc. (NYSE: CNO ), reported today that it ... made to the credit agreement include:, , ... June 30, 2010 to 32.5%, returning to 30% thereafter; , ... June 30, 2010, returning to 2.0x thereafter; , ...
... a series of informational custom printing product videos. The laser membership ... insights into the product uses, materials and options. , ... ... membership cards video includes a quality mix of visuals supported by ...
... Through Simple IngredientsLA JOLLA, Calif., March 31 ... announced the launch of Island Vanilla(TM), a wheat ... to create a wholesome, naturally sweet breakfast paradise.(Logo: ... unique flavor that Island Vanilla brings ...
Cached Medicine News:Health News:GUMC researcher creates first Web-interactive CME course for physicians on pharmaceutical marketing 2Health News:GUMC researcher creates first Web-interactive CME course for physicians on pharmaceutical marketing 3Health News:DecisionView Board of Directors Appoints James P. Scullion as CEO and President 2Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 2Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 3Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 4Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 5Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 6Health News:AARP Financial Inc. Survey Finds: Vast Majority of Families Struggle With Financial Implications of a Life Crisis 7Health News:Conseco Closes Amendment to Credit Facility 2Health News:Conseco Closes Amendment to Credit Facility 3Health News:Conseco Closes Amendment to Credit Facility 4Health News:My1Stop.com Launches Suite of Online Custom Printing Videos Beginning with Laser Membership Cards 2Health News:Kashi Company Expands With New Island Vanilla(TM) Biscuit Cereal 2
(Date:1/22/2015)... Jan. 22, 2015 /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" ... on Omega-3 therapies for cardiovascular disease and overall health is ... accomplishments in 2014 and its outlook for 2015 from the ... Shareholders, We would like to take this opportunity ...
(Date:1/22/2015)...  Bio-Techne Corporation (NASDAQ: TECH ) announced today ... the new Simple Plex platform through its Proteins Platform ... re-branding of the previously acquired CyPlex instrument platform from ... transformative immunoassay technology which integrates an innovatively designed microfluidic ...
(Date:1/22/2015)... 2015 Increasing sophistication among enterprise buyers of language ... in 2015, says Moravia CMO, Renato ... by market research firm Common Sense Advisory, 15 percent ... translation and localization needs. "From a language industry perspective, ...
Breaking Medicine Technology:Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7Bio-Techne Launches Simple Plex Platform 2Bio-Techne Launches Simple Plex Platform 3Moravia Sees Single-Sourcing as Key Localization Trend in 2015 2
... 29, 2011 Laboratory Supply Company (LABSCO), the largest ... products to hospitals, physician office laboratories, reference labs and ... to expand its executive leadership team with the new ... financial officer. Willett,s career has included over ...
... 2011 Masimo (NASDAQ: ... & Welfare (MHLW) and Health Canada regulatory clearances of Masimo ... conveniently measure total hemoglobin (SpHb®), SpO2, perfusion index, and pulse ... Hemoglobin is one of the most commonly ordered tests in ...
Cached Medicine Technology:LABSCO Hires George Willett as New Vice President and Chief Financial Officer 2Masimo Pronto-7™ Receives Japanese and Canadian Regulatory Clearances 2Masimo Pronto-7™ Receives Japanese and Canadian Regulatory Clearances 3Masimo Pronto-7™ Receives Japanese and Canadian Regulatory Clearances 4Masimo Pronto-7™ Receives Japanese and Canadian Regulatory Clearances 5
... IMMULITE 2500 is a high-throughput immunoassay system ... the IMMULITE 2000 with the important addition ... ,allows assays to be designed for optimal ... ,This allows for critical assays such as ...
AxSYM Myoglobin is a Microparticle Enzyme Immunoassay (MEIA) for the quantitative determination of myoglobin in human serum or plasma on the AxSYM System....
IRMA kit for detection of the cardiac marker Myoglobin...
... is an immunometric ('sandwich') EIA ... Prolactin in human serum or ... is bound by 2 anti-Prolactin ... One antibody is attached to ...
Medicine Products: