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Type of viral infection of eye associated with disease causing blindness in the elderly
Date:5/21/2012

mmune system's function is reduced, the virus proliferates, and the production of VEGF increases.

Identifying human cytomegalovirus as a cofactor in the development of AMD opens up new paths for the treatment of AMD, Dix said. One route could include reducing the viral load the amount of the human cytomegalovirus in the blood stream by treatment with an antiviral drug known as ganciclovir.

Additional research paths include looking at the genetics involved in the upregulation of VEGF by human cytomegalovirus.

"If we can knock down a certain gene or genes of the virus that stimulates VEGF production, we might be able to decrease it production and minimize AMD," Dix said.


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Contact: Jeremy Craig
jcraig@gsu.edu
404-413-1357
Georgia State University
Source:Eurekalert

Page: 1 2

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