Navigation Links
Type of connection procedure after pancreatic surgery influenced rate of pancreatic fistula
Date:4/30/2009

(PHILADELPHIA) After surgery to remove the head of the pancreas, invagination of the pancreas into the small intestine resulted in a lower rate of pancreatic fistula, according to researchers at the Jefferson Pancreas, Biliary and Related Cancer Center. The research was published in the Journal of the American College of Surgeons. It was performed as a randomized trial the gold standard for studies.

Removing the head of the pancreas, a procedure called pancreaticoduodenectomy (PD), is a common treatment for benign and malignant pancreatic diseases. Pancreatic fistula, a leakage of pancreatic secretions, represents healing failure of the pancreatic reconnection. It is a common complication of PD, affecting approximately 20 percent of patients. The development of pancreatic fistula has been associated with several factors, including soft pancreas texture and surgical technique. It can result in prolonged hospitalization and other complications.

Prior to this study, the role of the type of pancreas-intestine reconnection procedure, known as pancreaticojejunostomy (PJ), in the development of pancreatic fistula had not been as well-studied , according to Adam Berger, M.D., associate professor in the department of Surgery of Jefferson Medical College at Thomas Jefferson University.

"We actually hypothesized that a duct-to-mucosa PJ procedure would result in fewer pancreatic fistulas," Dr. Berger said. "However, the rate of pancreatic fistula was almost double in patients who received the duct-to-mucosa PJ compared to the invagination PJ."

Dr. Berger and colleagues at Jefferson and Indiana University randomized 197 patients who were undergoing PD to receive either an invagination PJ or a duct-to-mucosa PJ. In the duct-to-mucosa cohort, the rate of pancreatic fistula was 24%. In the invagination cohort, the fistula rate was 12%. The greatest risk factor was pancreatic texture: 27% of patients with a soft gland developed pancreatic fistula, compared with 8% of patients with hard glands.

"There currently is no standard PJ performed after surgery, since the data have not indicated that one is better than the other for patients," Dr. Berger said. "These data suggest that invagination PJ may be the best choice."


'/>"/>

Contact: Emily Shafer
emily.shafer@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Related medicine news :

1. Center to Expose and Close Animal Factories to Hold Media Teleconference Tomorrow to Discuss Smithfield Operations, Connection to Swine Flu, Health and Enviro Impacts
2. Meaningful Connections Offers Guidance, Case Examples for use of Electronic Health IT to Support Patient Centered Medical Home
3. Seniors Invited to Learn About Fraud Prevention at SCAN Connections Resource Center on April 28
4. American Cancer Society Launches Major Brand Revitalization Effort to Help Broaden Consumer Understanding and Connections
5. NotifySync™ Provides BlackBerry a Direct Connection to Any Email Platform Supporting Microsoft ActiveSync
6. Migraine Poetry Contest Kicks Off at HealthCentrals MyMigraineConnection.com
7. Social Disconnection in African American Women With Breast Cancer
8. Selflessness, core of all major world religions, has neuropsychological connection
9. DaVita Inc. Announces Receipt of DOJ Subpoena in Connection with Previously Reported Investigation
10. Providence Service Corporation Retains UBS Investment Bank as its Financial Advisor in Connection With the Sale of Certain Non-Strategic Assets
11. Thermage Schedules Shareholder Meeting for Vote on the Issuance of Common Stock in Connection With the Reliant Acquisition
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... ... meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s to ... and tested to meet the highest standard. , These products are also: ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical ... Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. ... honor of Morris F. Collen, a pioneer in the field of medical informatics, this ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... drug delivery system that we intend to develop to enable prevention of a ... lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... On Saturday, ... a treadmill relay – Miles by Moonlight to raise money for the American Heart ... or more. , Teams will work together to keep their treadmills moving for ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  True Health, a ... amplified its effort during National Breast Cancer Awareness ... cancer risks. ... Oncology calculated that more than 10 million American ... mutations in BRCA1 or BRCA2 and have not had ...
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance ... a medical-grade battery-powered display stand specifically designed for endoscopy environments. An ... technology into a clinical solution to support the improvement of patient ... Innovative Design ... Wireless Solution ...
(Date:10/7/2017)... --  Provista, a proven leader in the supply ... power, today announced a new resource area on Provistaco.com ... is the online home for case studies, articles on ... releases, slideshows and events. ... at their fingertips, viewers can also watch short videos ...
Breaking Medicine Technology: