Navigation Links
Type 2 diabetes may be caused by intestinal dysfunction
Date:3/5/2008

has become increasingly evident that the gastrointestinal tract plays an important role in energy regulation, and that many gut hormones are involved in the regulation of sugar metabolism. "It should not surprise anyone that surgically altering the bowel's anatomy affects the mechanisms that regulate blood sugar levels, eventually influencing diabetes," Dr. Rubino says.

While other gastrointestinal operations may cure diabetes as an effect of changes that improve blood sugar levels, Dr. Rubino's research findings in animals show that procedures based on a bypass of the upper intestine may work instead by reversing abnormalities of blood glucose regulation.

In fact, bypass of the upper small intestine does not improve the ability of the body to regulate blood sugar levels. "When performed in subjects who are not diabetic, the bypass of the upper intestine may even impair the mechanisms that regulate blood levels of glucose," says Dr. Rubino. In striking contrast, when nutrients' passage is diverted from the upper intestine of diabetic patients, diabetes resolves.

This, he explains, implies that the upper intestine of diabetic patients may be the site where an abnormal signal is produced, causing, or at least favoring, the development of the disease.

How exactly the upper intestine is dysfunctional remains to be seen. Dr. Rubino proposes an original explanation known in the scientific community as the "anti-incretin theory."

Incretins are gastrointestinal hormones, produced in response to the transit of nutrients, that boost insulin production. Because an excess of insulin can determine hypoglycemia (extremely low levels of blood sugar) -- a life-threatening condition -- Dr. Rubino speculates that the body has a counter-regulatory mechanism (or "anti-incretin" mechanism), activated by the same passage of nutrients through the upper intestine. The latter mechanism would act to decrease both the secretion and the action of
'/>"/>

Contact: John Rodgers
jdr2001@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. DFW Partnership for Peak Health Care Performance Selects Data Aggregator for Diabetes Treatment Program
2. White Hat Brands, Juvenile Diabetes Research Foundation Offer the Juice on New Partnership
3. Physicians Wellness Network and Home Access Health to Provide Medically Compliant Diabetes Testing Sold Directly to Consumers
4. Video: DIVABETIC - Makeover Your Diabetes Kicks Off 2008 Events
5. Mayo Researchers Look for Explanation Behind High Incidence of Diabetes Among Asian Indians
6. Marker for Diabetes Might Miss Early Vision Complication
7. Mayo researchers look for explanation behind high incidence of diabetes among Asian Indians
8. Randy Jackson and the American Heart Association Educate Minneapolis Area about the Connection between Type 2 Diabetes and Cardiovascular Disease
9. Randy Jackson and the American Heart Association Educate Cincinnati Area Residents about the Connection between Type 2 Diabetes and Cardiovascular Disease
10. Johnson & Johnson Diabetes Institute, LLC Launches New Center to Provide State-of-the-Art Education, Training to Health Professionals
11. ADVANCE diabetes trial results confirm no evidence of safety risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... City, OK (PRWEB) July 22, 2014 ... the launch of the newest component of its existing ... area hospital within the regional SSM Health Care of ... affiliate health centers that shares its services with an ... primary care centers across several states. As a forward-thinking ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 DocbookMD ... process of deploying one of the largest physician-centric mobile ... ( MHMD ) in Houston. , Created by Austin-based ... the DocbookMD application will be embedded into MHMD’s Accountable ... searched for the best technology to put this capability ...
(Date:7/22/2014)... Dr. Dental is excited to announce the redesign ... in mind, one of the main differences from the old ... navigation very easy. Dr. Dental is renowned for having exceptional ... dentist affordable, convenient and fun, and the new website mirrors ... appointment scheduling system right on the home page where a ...
(Date:7/22/2014)... 22, 2014 A Florida woman has ... that alleges the death of her husband was the ... thinner, Bernstein Liebhard LLP reports. According to her complaint, ... for the Southern District of Florida on June 23rd, ... suffered a subdural hemorrhage the following June. Despite emergency ...
(Date:7/22/2014)... hysterectomy using electric power morcellation, uterine cancers were present ... the procedure, according to a study published by ... in which the uterus is fragmented into smaller pieces, ... Despite the commercial availability of electric power morcellators for ... at the time of electric power morcellation (in this ...
Breaking Medicine News(10 mins):Health News:St. Anthony Hospital Expands Its Telemedicine Program with Telepsychiatry 2Health News:St. Anthony Hospital Expands Its Telemedicine Program with Telepsychiatry 3Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 2Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 3Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 4Health News:Dr. Dental Reveals Exciting New Website 2Health News:Xarelto Lawsuit Filed by Florida Woman Alleges Uncontrollable Bleeding Led to Husband’s Death, Bernstein Liebhard LLP Reports 2Health News:Xarelto Lawsuit Filed by Florida Woman Alleges Uncontrollable Bleeding Led to Husband’s Death, Bernstein Liebhard LLP Reports 3Health News:Study examines presence of uterine cancers at the time of hysterectomy using morcellation 2
... , March 10 Smart Balance, Inc. (Nasdaq: SMBL ) announced today that Stephen Hughes , Chairman and Chief Executive Officer of Smart Balance, ... Tuesday, March 16, 2010 . , ... , , ... ...
... technological revolution, the "light fantastic" continues to impact people,s ... and performing intricate surgery. As the golden anniversary of ... 7th, Chemical & Engineering News (C&EN), ACS, weekly newsmagazine, ... exciting future of this amazing invention. C&EN ...
... may someday extend men,s lives, , WEDNESDAY, March 10 ... in treating late-stage prostate cancer, it often results in ... to such therapy. , Now, however, researchers working with ... the secondary tumors gain their resistance -- a finding ...
... ... investment banking and business development to LeveragePoint,s Board of Directors. , ... Cambridge, MA (PRWEB) March 10, ... Value Management software for marketing and sales, today announced that entrepreneurial advisor and seasoned ...
... ... ... , , , , ... ...
... , ... ... , , , ... ...
Cached Medicine News:Health News:Smart Balance to Present at Roth Growth Stock Conference 2Health News:Scientists Find Key to Hormone-Resistant Prostate Tumors 2Health News:Scientists Find Key to Hormone-Resistant Prostate Tumors 3Health News:Peyton Marshall Joins LeveragePoint Innovations Board 2Health News:Peyton Marshall Joins LeveragePoint Innovations Board 3Health News:Maryland Legislation Introduced to Prohibit Indoor Tanning for Minors 2Health News:Maryland Legislation Introduced to Prohibit Indoor Tanning for Minors 3Health News:Maryland Legislation Introduced to Prohibit Indoor Tanning for Minors 4Health News:Maryland Legislation Introduced to Prohibit Indoor Tanning for Minors 5Health News:Maryland Legislation Introduced to Prohibit Indoor Tanning for Minors 6Health News:Celebrate National Nutrition Month and St. Patrick's Day, Go Green With Pistachios - The Only Green Nut! 2Health News:Celebrate National Nutrition Month and St. Patrick's Day, Go Green With Pistachios - The Only Green Nut! 3Health News:Celebrate National Nutrition Month and St. Patrick's Day, Go Green With Pistachios - The Only Green Nut! 4Health News:Celebrate National Nutrition Month and St. Patrick's Day, Go Green With Pistachios - The Only Green Nut! 5
(Date:7/22/2014)... -- BioDelivery Sciences International, Inc. (BDSI) (NASDAQ: ... appointed Charles J. (Chuck) Bramlage and Dr. ... Board.  Mr. Bramlage is a veteran ... and other commercial functions.  He is currently the Chief ... company that was recently acquired by AstraZeneca and is ...
(Date:7/22/2014)... July 22, 2014  Pressure BioSciences, Inc. ... Parabase Genomics ("Parabase"), (together "the companies"), today ... research and development agreement (the "collaboration"). Under ... develop a front-end, sample preparation method for ... confirmatory testing process. The sample preparation method ...
(Date:7/22/2014)... Quantum Materials Corporation (OTCQB:QTMM) (QMC) announced today the addition of ... to the Board of Directors. QMC also announced formation of a ... Chief Science Officer and Board of Directors Member, along with Scientific ... and Mr. Tomio Gotoh , a pioneer of the Personal ... Quantum Materials welcomes two new outside Board members, Mr. ...
Breaking Medicine Technology:BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 2BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 3BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 4BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 5BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 6BioDelivery Sciences Appoints Charles J. Bramlage and Dr. Barry I. Feinberg to its Board of Directors 7Pressure BioSciences to Develop Front-end Sample Preparation for Parabase Genomics' Targeted Next Generation Sequencing Testing Platform 2Pressure BioSciences to Develop Front-end Sample Preparation for Parabase Genomics' Targeted Next Generation Sequencing Testing Platform 3Pressure BioSciences to Develop Front-end Sample Preparation for Parabase Genomics' Targeted Next Generation Sequencing Testing Platform 4Quantum Materials Announces New Outside Directors and Adds Scientific Advisory Board 2Quantum Materials Announces New Outside Directors and Adds Scientific Advisory Board 3Quantum Materials Announces New Outside Directors and Adds Scientific Advisory Board 4
... YORK, Oct. 14 Reportlinker.com announces that a ... catalogue: Colorectal Cancer - France ... http://www.reportlinker.com/p0312710/Colorectal-Cancer---France-Drug-Forecasts-and-Treatment-Analysis-to-2020.html ... Analysis to 2020 SummaryGlobalData, the ...
... Oct. 14 Cumberland Pharmaceuticals Inc. (Nasdaq: ... today announced that Acetadote® ( acetylcysteine ) Injection, ... is now commercially available in the Australian market. Phebra ... exclusive license from U.S.-based Cumberland Pharmaceuticals to market and ...
Cached Medicine Technology:Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 2Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 3Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 4Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 5Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 6Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 7Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 8Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 9Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 10Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 11Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 12Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 13Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 14Reportlinker Adds Colorectal Cancer - France Drug Forecasts and Treatment Analysis to 2020 15Cumberland Pharmaceuticals and Phebra Pty Ltd. Announce the Launch of Acetadote® in Australia 2Cumberland Pharmaceuticals and Phebra Pty Ltd. Announce the Launch of Acetadote® in Australia 3Cumberland Pharmaceuticals and Phebra Pty Ltd. Announce the Launch of Acetadote® in Australia 4Cumberland Pharmaceuticals and Phebra Pty Ltd. Announce the Launch of Acetadote® in Australia 5
... matrix constructed of cross-linked collagen fibers ... through a proprietary 360 accretion process. ... aspirate, Healos provides an excellent environment ... differentiation. The hydroxyapatite-coated collagen microfibers in ...
Sharp Weitlaner Retractor....
Weitlaner retractor, blunt....
Bruns (Volkmann) bone curette, with Novotex plastic handle (autoclavable in autoclave up to 143C by 3 bar), 9, oval....
Medicine Products: