Navigation Links
Type 2 Diabetes Drug May Increase Fracture Risk

Study adds to evidence of possible link between thiazolidinediones and bone fractures, researchers say

MONDAY, Sept. 28 (HealthDay News) -- Patients who take the diabetes drugs known as thiazolidinediones may be at higher risk of bone fracture, new research suggests.

In the study, Dr. Ian Douglas of the London School of Hygiene and Tropical Medicine and colleagues searched a database of more than 6 million patients in the United Kingdom and found 1,819 people aged 40 and older who had had a bone fracture and had been prescribed a type of thiazolidinedione. The drugs were introduced in the 1990s and are used to treat type 2 diabetes.

After adjusting their figures to account for the fact that older people are more likely to break bones, the researchers found that those taking thiazolidinediones had almost 1.5 times as many fractures while taking the drugs as they did when they weren't taking the drugs. The risk grew the longer the people took the medications.

The findings support previous research that has suggested a link between these medications and bone fractures. But the researchers acknowledge that the study didn't follow the gold standard of research, which is to randomly assign people to take the drug or not take it.

Still, Douglas and colleagues conclude that the findings "should be taken into consideration in the wider debate surrounding the possible risks and benefits of treatment with thiazolidinediones."

The study appears in the Sept. 29 online edition of the journal PLoS Medicine.

More information

Learn more about diabetes from the American Diabetes Association.

-- Randy Dotinga

SOURCE: Public Library of Science, news release, Sept. 28, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Irregular Heartbeat Risk Higher in Women With Type 2 Diabetes
2. Diabetes Informational Site Offers Free Glucose Monitor
3. Video: Making Sense of Diabetes Video Contest Asks What Does Diabetes Taste, Smell or Sound Like to You?
4. New Presentation Highlights Importance of In-Hospital Hyperglycemia Management and Appropriate Discharge Planning for Diabetes Patients
5. People with type 2 diabetes improved muscular strength
6. Research: People With Type 2 Diabetes Improved Muscular Strength and Exercise Capacity Through Physical Therapist Exercise Counseling Combined With Fitness Center Exercise Training
7. Bayer Introduces CONTOUR USB - The First Blood Glucose Meter With Unique Plug & Play Diabetes Management Software
8. Eight-Year-Olds All American Paint Scheme Walks Away With Ford Customer Service Divisions Funny Car Design Contest to Support Juvenile Diabetes Research Foundation
9. Anthem Blue Cross and Blue Shield Foundation Grant Supporting American Diabetes Associations Family Link Program In Connecticut
10. TBGH Report on Status of Diabetes in Texas Indicates Growing Severity of Problem and Higher Cost of Care Than National Average
11. Diabetes Medications Dont Lower Inflammation
Post Your Comments:
(Date:11/25/2015)... ... ... Dr. John Pierce, Medical Director at the Ageless Forever clinic in Las ... Pro laser therapy cap. FDA cleared for safety and efficacy, the Capillus272 offers men ... surgery, prescription pills, or topical foams. , “Capillus272™ Pro is a home-use device ...
(Date:11/25/2015)... ... 2015 , ... On November 10, 2015, Bohrer Brady, LLC filed a class ... of a home health care worker who provided companionship services for the elderly, ill ... employed by Humana, Inc., Humana at Home, Inc., and SeniorBridge Family Companies (CT), Inc. ...
(Date:11/25/2015)... ... November 25, 2015 , ... According to an article ... being more and more widely heralded as a breakthrough for performing hernia repairs. The ... over traditional laparoscopic surgery is that it can greatly reduce the pain that a ...
(Date:11/25/2015)... ... November 25, 2015 , ... Dental professionals who would like to ... are invited to attend Dr. Mark Iacobelli’s Advanced Implant Mentoring (AIM) CE course. Courses ... , As the co-founders of Advanced Implant Mentoring (AIM), Dr. Iacobelli and Dr. ...
(Date:11/25/2015)... ... November 25, 2015 , ... Wimbledon ... programs, launches new Wimbledon Athletics Facebook page to educate the public, ... unsuspected cardiac abnormalities. About 2,000 people under the age of 25 die from ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... ATLANTA , Nov. 25, 2015 ... the first federal bellwether trial against Wright Medical ... relating to their Conserve metal-on-metal hip implant device, ... Christiansen.  Following a two week trial and three ... Conserve metal-on-metal hip device was defectively designed and ...
(Date:11/25/2015)... 25, 2015  Trovagene, Inc. (NASDAQ: TROV ), ... Chief Executive Officer Antonius Schuh, Ph.D., is scheduled to ... Annual Piper Jaffray Healthcare Conference. th ... Palace Hotel in New York ... Mr. Schuh will be available for one-on-one meetings during ...
(Date:11/25/2015)... YORK , November 25, 2015 ... market of self-monitoring blood glucose devices was valued at ... grow with a CAGR of 5.7% during 2015 - ... geriatric population and increasing prevalence of diabetes. In addition, ... diabetes care is also contributing to the growth of ...
Breaking Medicine Technology: