Navigation Links
Type 1 diabetes research at UC San Diego gets $5 million boost
Date:9/27/2010

Maike Sander, MD, associate professor of pediatrics and cellular & molecular medicine at the University of California, San Diego School of Medicine has been awarded nearly $5 million by the Beta Cell Biology Consortium (BCBC) to lead an interdisciplinary team in cell therapy research for type 1 diabetes. Sander will lead a team of domestic and international collaborators, with the aim of generating replacement insulin-producing beta cells from patient-derived induced pluripotent stem cells.

The $4,950,000 grant is shared with Karl Willert, PhD, director of the UCSD Human Stem Cell Core Facility, who will apply a screening platform for cellular microenvironments to beta cell differentiation (the process by which cells become progressively more specialized.) Additional participants include labs at the University of Pennsylvania and in Barcelona, Spain, as well as a San Diego-based biotech company.

Sander is a physician-scientist with UCSD's Pediatric Diabetes Research Center (PDRC). Launched the summer of 2008, the PDRC brings together top-ranked physicians and research scientists to investigate the causes and cure of type 1 diabetes.

Type 1 diabetes can occur at any age; however, half of the patients are diagnosed before the age of 20. Though the exact cause is unknown, genetics, viruses, and environmental factors are thought to play a role in causing the autoimmune response that eventually leads to beta cell destruction.

The major focus of Sander's current research is to understand the molecular mechanisms underlying the ability of pluripotent stem cells, or progenitor cells, to produce the different cell types of the pancreas. Specifically, she and her team want to be able to instruct patient-derived pluripotent stem cells to become beta cells.

Since the first pioneering work on islet transplantation, it has become clear that a cell-based approach for the treatment of type 1 diabetes can have significant benefits in terms of insulin independence and a reduced risk of hypoglycemia.

"Right now, scientists can create pancreatic progenitor cells from human embryonic stem cells. However, our goal is to take it a step further and make replacement beta cells from the patient's own tissue," Sander said. "This grant is a perfect example of collaboration and translational medicine for a greater cause. It's not about who discovers the cure first. It's about finding a cure fast."


'/>"/>

Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California -- San Diego
Source:Eurekalert  

Related medicine news :

1. OHSU research team joins elite consortium dedicated to curing type 1 diabetes
2. Congressman to speak at meeting on diabetes and obesity
3. Drug holds promise to halt debilitating condition of diabetes
4. Immune System Genes Show Links to Type 1 Diabetes
5. Diabetes Drug Metformin Linked to Lower Lung Cancer Rate in Mice
6. New study singles out factors linked to cognitive deficits in type 2 diabetes
7. Moms who dont breastfeed more likely to develop type 2 diabetes
8. Diabetes impairs but does not halt sex among older adults
9. Link Between Diabetes, Alzheimers Disease Strengthened
10. Heart Risks the Same With 2 Diabetes Drugs: Study
11. Fat distribution plays a role in weight loss success in patients at risk of diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Type 1 diabetes research at UC San Diego gets $5 million boost
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th ... Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, ... The fun run is geared towards children of all ages; it is a non-competitive, ...
(Date:10/13/2017)... ... 2017 , ... Talented host, actor Rob Lowe, is introducing ... new episode of "Success Files," which is an award-winning educational program broadcasted on ... subject in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve ...
(Date:10/13/2017)... ... , ... “The Journey: From the Mountains to the Mission Field”: the story ... the Philippines. “The Journey: From the Mountains to the Mission Field” is the creation ... has taught all ages and currently teaches a class of ladies at her church, ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... advisory services for healthcare compliance program management, will showcase a range of technology ... Association for Assisted Living (NCAL) Convention and Expo to be held October 14–18, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... IRVING, Texas , Oct. 11, 2017  Caris ... science focused on fulfilling the promise of precision medicine, ... Institute has joined Caris, Precision Oncology Alliance™ (POA) as ... leading cancer centers, the St. Jude Crosson Cancer Institute ... to advance the use of tumor profiling, making cancer ...
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical Services, ... solutions for injectable drug administration, today shared the results ... Adapter for improving the intradermal administration of polio vaccines. ... Vaccination Summit in May 2017 by Dr. Ondrej ... Department, World Health Organization (WHO), and recently published in ...
(Date:10/4/2017)... -- According to the Centers for Disease Control and Prevention (CDC), influenza ... Care is helping communities across Massachusetts , ... no-cost* flu shots through the end of the month. *Some ... ... flu shot is by the end of October, according to the Centers ...
Breaking Medicine Technology: