Navigation Links
Type 1 Diabetes Treatment Disappoints in Trial
Date:2/2/2012

al research at the University of Miami's Diabetes Research Institute, said that about 80 percent of people with type 1 likely have GAD65 autoantibodies.

GAD-alum was designed to work like a vaccine, hopefully stopping the autoimmune attack soon after it has begun, to preserve beta cell function.

"GAD-alum takes a vaccine kind of approach, and takes the antigen in the autoimmune disease and tries to give it in a way that will vaccinate people so they don't have the destructive autoimmunity," explained Skyler.

Previous research, done by the same group, showed positive effects from the treatment, especially in those treated less than six months after being diagnosed with type 1 diabetes, according to the study.

The current study included 334 people between the ages of 10 and 20. All had type 1 diabetes for less than three months, and they had GAD autoantibodies.

The patients were randomly assigned to one of three treatment groups: four doses of GAD-alum; two doses of GAD-alum followed by two doses of placebo; or four doses of placebo.

The most important measure the researchers looked for was levels of C-peptide. C-peptide is a byproduct of insulin production, so rising levels of C-peptide indicate increased levels of insulin. The researchers also measured how much insulin people needed, their average blood sugar levels over the study period, and how often they experienced low blood sugar levels.

While GAD-alum appeared safe and was very well tolerated in this study, it didn't significantly reduce levels of C-peptide, improve blood sugar levels or lessen the need for insulin, according to the study.

Ludvigsson said there may be several reasons that the initial research looked promising, yet this study failed to deliver positive results. One is that they allowed flu vaccines to be given at the same time this trial was ongoing, which could have affected the immune system response somehow, he said. Also, the age of the pati
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Neighborhood socioeconomic status and diabetes
2. NACDD Receives Two-Year Grant From Merck & Co., Inc. to Improve Diabetes Education
3. International Diabetes Federation awards $2 million to 9 global diabetes research projects
4. Diabetes drug ups risk for bone fractures in older women
5. Diabetes Drugs Avandia, Actos Tied to Fractures in Women
6. Fishy Smell May Keep Patients From Diabetes Drug
7. Small Increase in Diabetes Risk Noted in Statin Patients
8. FDA Approved Diabetes Drug Despite Hints at Cancer Risk
9. Remove Diabetes Drug Avandia From Market: FDA Reports
10. Remove Diabetes Drug Avandia From Market: FDA Documents
11. Excessive Weight Gain During Pregnancy Raises Gestational Diabetes Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Type 1 Diabetes Treatment Disappoints in Trial
(Date:11/23/2014)... Locks-Magnetic.com, a notable magnetic locks maker, has ... new products are available at low rates up to ... of the new emergency doors. The emergency door adopts ... choose from several colors. All of the products are ... release is not as easy as many people think. ...
(Date:11/23/2014)... AngelWeddingDress.com has recently updated its ... beach wedding dresses. “If you are looking for gorgeous ... soon as possible. Here you can enjoy 70% off ... , Holding a big marriage ceremony is the most ... beach wedding dress is uppermost priority. Ophelia, one of ...
(Date:11/23/2014)... November 23, 2014 Wright & Schulte ... of Ohio and West Virginia residents who allege that ... health disorders due to drinking C8 contaminated water ... West Virginia. According to the C8 complaints, the plaintiffs ... worked or lived in at least one of the ...
(Date:11/22/2014)... (PRWEB) November 23, 2014 Cancer researchers ... a connection between intercellular communication tunnels and the growth ... the full story on the Surviving Mesothelioma website. ... and the University of Minnesota have just released their ... information and materials between cells. They found that ...
(Date:11/22/2014)... 2014 BambooFlooringChina.com is a famous ... proudly released its new collection of bamboo mats ; ... to 29% off. , According to the sales ... grass, making it a highly renewable resource. Their bamboo mats ... mixing color which comes from natural bamboo with caramel bamboo ...
Breaking Medicine News(10 mins):Health News:Beach Wedding Dresses Added to Outstanding Online Dress Company AngelWeddingDress.com 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 3Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 4Health News:Study Links Cellular ‘Tunnels’ to Mesothelioma Proliferation, According to Surviving Mesothelioma 2Health News:Trendy Bamboo Mats Online Now By BambooFlooringChina.com 2
... One in eight parents reported that his or ... laboratory testing and/or appointments with specialists during the ... payment, according to a study, presented Sunday, Oct. 3, ... and Exhibition in San Francisco. For the ...
... , FRIDAY, Oct. 1 (HealthDay News) -- Doctors who take ... lifestyle habits to their patients than doctors who gobble down ... hit the gym, according to new research. Additionally, the ... they,d been well-trained to counsel their patients on lifestyle changes ...
... identify obscure cartoon characters than the native plants and animals ... connection to the natural world can have a profound impact ... author who coined the phrase, "nature-deficit disorder," will address this ... Pediatrics (AAP) National Conference & Exhibition Saturday, Oct. 2. His ...
... department at a mid-sized hospital were able to increase ... for measuring general technologist productivity, according to a study ... American College of Radiology ( www.jacr.org ). ... priorities that may be difficult to achieve simultaneously," said ...
... Johns Hopkins scientists have discovered a way to turn off ... mice, a discovery that could have implications for the millions ... peanuts and milk. The findings, published online in the ... could be trained to tolerate food allergies that lead to ...
... review article published in the October issue of ... Clinic physicians differentiate the ethical and legal permissibility ... comfort measures, specifically palliative sedation, from that of ... that palliative sedation has an important place on ...
Cached Medicine News:Health News:1 in 8 parents forgoes pediatrician-recommended care 2Health News:Doctors' Health, Well-Being Affect Patient Counseling 2Health News:Doctors' Health, Well-Being Affect Patient Counseling 3Health News:Johns Hopkins researchers turn off severe food allergies in mice 2
(Date:11/21/2014)... DUBLIN, Ohio and MELVILLE, N.Y. ... (NYSE: CAH ), one of the world,s ... (NASDAQ: HSIC ), the world,s largest provider ... animal health and medical practitioners, today announced that the ... provide one of the most comprehensive service and product ...
(Date:11/21/2014)... Nov. 20, 2014  RedRick Technologies, a provider ... reading room environment guidance, has helped the new ... reading room, which may also serve as a ... Medicine. "In line with the ... of Radiology,s Imaging 3.0 ™ initiative, the ...
(Date:11/21/2014)... 20, 2014 Depomed, Inc. (NASDAQ: DEPO ) ... 26 th Annual Healthcare Conference in New York ... conference is scheduled for 8:00 am EST (5:00 am PST) on ... webcast can be accessed via the Investor Relations page of the ... will be archived for 30 days on the company,s website. ...
Breaking Medicine Technology:Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 2Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 3Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 4Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 5RedRick Technologies Helps Penn Radiology Implement New Radiology Reading Room Concepts 2RedRick Technologies Helps Penn Radiology Implement New Radiology Reading Room Concepts 3Depomed To Present At Piper Jaffray 26th Annual Healthcare Conference 2
... 2011 Varian Medical Systems (NYSE: VAR ... to support the company,s ongoing growth and safety initiatives. ... for the company, has been named Chief Operating Officer ... promotion, and sale of all Varian products and services ...
... PARSIPPANY, N.J., Oct. 3, 2011 To help frustrated ... to their chronic nasal congestion and trouble with sleep, ... Sperling,s BestPlaces to identify the 20 Most Congested Cities ... top 20 metropolitan areas where residents are most challenged ...
Cached Medicine Technology:Varian Medical Systems Announces New Management Positions 2Varian Medical Systems Announces New Management Positions 3Varian Medical Systems Announces New Management Positions 420 Most Congested Cities in U.S. Unveiled 220 Most Congested Cities in U.S. Unveiled 320 Most Congested Cities in U.S. Unveiled 4
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: