Navigation Links
Type 1 Diabetes Patients Need New Kidney Therapies: Study
Date:2/24/2011

THURSDAY, Feb. 24 (HealthDay News) -- Despite major advances in kidney care over the last two decades, type 1 diabetes patients with kidney dysfunction still have high rates of kidney failure and heart-related death, researchers have found.

The findings show that more effective treatments are needed for these patients, according to the authors of the new study.

One-third of type 1 diabetes patients develop macroalbuminuria, a condition where high amounts of protein are lost through the urine. These patients are at increased risk for kidney failure (end-stage renal disease) and death from heart-related causes, the researchers explained in a news release from the American Society of Nephrology.

The new study included 423 white patients with type 1 diabetes who developed macroalbuminuria and were enrolled in the study between 1991 and 2004. Most of the patients (98 percent) were followed through 2008.

During the follow-up, 172 patients developed end-stage renal disease, and 70 of these patients died. Another 29 study participants died before developing end-stage renal disease.

Between 1991 and 2008, more patients received treatments to protect their kidneys (treatments increased from 56 percent to 82 percent) and significant improvements were noted in patients' blood pressure and cholesterol levels. However, the risks for both end-stage disease and death before developing end-stage disease did not change over the study period.

The investigators also found that patients who had kidney transplants before they had to start dialysis were less likely to die.

"Our findings clearly indicate that the accomplishments in treatment of patients with type 1 diabetes and macroalbuminuria over the last 20 years are not effective enough, and more effective therapies to retard progression to end-stage renal disease are desperately needed," study author Dr. Andrzej Krolewski, of the Joslin Diabetes Center and Brigham and Women's Hospital in Boston, said in the news release.

"New therapies need to be developed including more aggressive or experimental protocols to stop or retard declining renal function, which leads to end-stage renal disease," Krolewski added.

The study was released online in advance of publication in an upcoming print issue of the Journal of the American Society of Nephrology.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about diabetes.

-- Robert Preidt

SOURCE: American Society of Nephrology, news release, Feb. 24, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Home urine test measures insulin production in diabetes
2. Fatty liver may herald impending Type 2 diabetes
3. Convenient blood test not as effective for diagnosing diabetes in children
4. Diabetes Social Networking Web Sites Vary in Quality
5. Dwarfism Mutation May Protect From Cancer, Diabetes
6. Researchers find brain insulin plays critical role in the development of diabetes
7. Early signs of heart disease in preadolescent children with type 1 diabetes
8. Trial will test whether surgery is the best option for type 2 diabetes
9. Experts call for greater awareness of the links between diabetes and kidney disease
10. Cold Viruses Appear Linked to Type 1 Diabetes
11. Researchers discover root cause of blood vessel damage in diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Type 1 Diabetes Patients Need New Kidney Therapies: Study
(Date:12/2/2016)... Raleigh, NC (PRWEB) , ... December 02, 2016 , ... ... the Open Enrollment Period (or Annual Election Period), is ending December 7th. Currently-enrolled Medicare ... plan (Part C) or prescription drug plan (Part D) need to make changes during ...
(Date:12/2/2016)... ... ... With the number of pain management programs available for people suffering with ... that works for them. When an inventor from Suisun City, Calif., was unsuccessful in ... share it with others. , He developed a prototype for PRO GO MASSAGE to ...
(Date:12/2/2016)... ... December 02, 2016 , ... Dr. Raffi ... be included in the 2016 “Guide to America’s Top Plastic Surgeons” for seven ... amalgamation of their education, experience, and professional associations. , One the most ...
(Date:12/2/2016)... ... December 02, 2016 , ... Mediaplanet is proud to announce ... covers the innovative treatments, therapeutic technologies, and revolutionized nutrition that are helping patients ... life 6 years in the last 3 decades,” says Dr. Valentine Fuster, a ...
(Date:12/2/2016)... Honolulu, Hawaii (PRWEB) , ... December 02, 2016 ... ... 3, 2016 at the Hyatt Regency Waikiki Beach Resort and Spa in Honolulu, ... (CME) in the field of pain management. , The demand for supplemental ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... -- Eli Lilly and Company (NYSE: LLY ) ... updated financial guidance for 2016 on Thursday, December 15, ... that day with the investment community and media to ... conference call will begin at 10 a.m. ET. Investors, ... webcast of the conference call through a link that ...
(Date:12/2/2016)... , December 2, 2016 Orthopedic ... & Support) is Expected to Gain a Significant Market Share ... Orthopedic Ailments  ... , According to a ... on Medical Implants Sterile Packaging: Clamshell Product Type Segment Projected ...
(Date:12/2/2016)... Research and Markets has announced the addition of ... Markets and Companies" to their offering. ... , , ... The market value of drug delivery technologies and the anticancer drugs ... according to organs involved and the types of cancer as well ...
Breaking Medicine Technology: