Navigation Links
Two-Drug Combo May Lower Diabetics' Kidney Risk
Date:2/19/2009

A pair of blood pressure medicines helps maintain proper organ function, study suggests

THURSDAY, Feb. 19 (HealthDay News) -- A combination of two blood pressure-lowering drugs reduced the risk of kidney disease by about 20 percent in people with type 2 diabetes, according to researchers who analyzed data from a study that included more than 11,000 patients.

The patients were randomly selected to receive either placebos or a combination of the angiotensin-converting enzyme (ACE) inhibitor perindopril and the diuretic indapamide. Most of the patients had high blood pressure, but 20 percent had normal blood pressure -- less than 130/80 mm Hg.

After an average follow-up of four years, patients taking the blood pressure-lowering drugs were 21 percent less likely to have kidney disease than those in the placebo group. The researchers also found that kidney function returned to normal among some patients who had early signs of diabetes-related kidney disease before they started taking the drugs.

Even in patients who didn't have high blood pressure, the drug combination reduced the risk of kidney disease.

More research is needed, but these results suggest that patients with type 2 diabetes might be considered for antihypertensive treatment even if they have normal blood pressure, said the authors of the study, which appears in the April issue of the Journal of the American Society of Nephrology.

The researchers noted their study did have important limitations, including the fact that it was an analysis of a previous clinical trail.

"Most of the findings related to early manifestation of kidney disease [albuminuria], and the study was not large enough to assess the impact of the intervention directly on the risk of kidney failure. We could not separate out the impact of the blood pressure-lowering combination used, or prove whether it had any effects beyond its blood pressure-lowering effects," study co-author Vlado Perkovic, of the George Institute for International Health in Sydney, Australia, added in an American Society of Nephrology news release.

More information

The National Kidney Foundation has more about diabetes and kidney disease.



-- Robert Preidt



SOURCE: American Society of Nephrology, news release, Feb. 18, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Two-Drug Combo Fights Brain Tumors
2. Two-Drug Combo Reduces Diabetic Kidney Damage
3. Two-Drug Treatment Didnt Improve Cardiac Arrest Survival Rates
4. Radiation and drug combo helps boost efficacy of lung cancer treatment
5. Aerobic, Weight Training Combo Best Against Diabetes
6. New antibiotic drug combo to speed up treatment of tuberculosis
7. Drug Combo Helps Fight Marfan Syndrome
8. Drug Combo Blocks Pain Without Impairing Movement
9. CPR, Defibrillator Combo Boosts Cardiac Incident Survival
10. Drug Combo Boosts Multiple Myeloma Survival
11. Drug Combos Effective Against Rheumatoid Arthritis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Two-Drug Combo May Lower Diabetics' Kidney Risk
(Date:5/26/2017)... ... May 26, 2017 , ... Rob Lowe acts as ... production of the series is on hiking in American. Viewers can reconnect with America ... great benefits of hiking. , Many consumers have looked for an inventive new place ...
(Date:5/26/2017)... ... May 26, 2017 , ... “THE FLINTHILLS FAMILY-Our Journey to the Cross”: the personal journey of ... Cross” is the creation of published authors, Bob and Margaret Massey. Bob Massey is ... is "panther quick and leather tough." His love for others is apparent in all ...
(Date:5/26/2017)... ... ... Jack: Against All Odds”: the story of Coach Cactus Jack and the impact he ... creation of published author, Walter Hubbard, a retired wildlife and fisheries biologist and pharmacy ... Walter and Jane have three adult children and a granddaughter. Walter and ...
(Date:5/24/2017)... ... May 24, 2017 , ... In ... choosing the most appropriate instruments for research and understanding the basic principles that ... webinar will focus on innovations in stereo microscopy for brightfield and fluorescence typically ...
(Date:5/24/2017)... California (PRWEB) , ... May 24, 2017 , ... ... through innovative medical image management and interpretation, has received U.S. Food and Drug ... , Nucleus.io is a web-based, scalable and secure cloud platform for medical image ...
Breaking Medicine News(10 mins):
(Date:5/15/2017)... Inc., a privately-held CNS pharmaceutical company based in ... disease (PD), has enrolled the first patient in the RASMET ... study involving patients with PD and taking place at 12 ... period. The first stage is open label and involves single ... Denver , Boca Raton ...
(Date:5/10/2017)... Global Health Intelligence (GHI), the leading healthcare data analytics ... 2017 ranking of the Best-Equipped Hospitals in Latin America ... GHI,s hospitals database for Latin America , which is ... database covers 86% of the hospitals in Latin ... each institution in key areas such as beds, medical specialties, ...
(Date:5/9/2017)... -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), ... has earned a spot on Forbes, "America,s ... ranked among 500 U.S. employers as well as in ... Services. The annual Forbes rankings ... of over 30,000 employees across 25 industries. The survey ...
Breaking Medicine Technology: