Navigation Links
Two-Drug Combo May Lower Diabetics' Kidney Risk

A pair of blood pressure medicines helps maintain proper organ function, study suggests

THURSDAY, Feb. 19 (HealthDay News) -- A combination of two blood pressure-lowering drugs reduced the risk of kidney disease by about 20 percent in people with type 2 diabetes, according to researchers who analyzed data from a study that included more than 11,000 patients.

The patients were randomly selected to receive either placebos or a combination of the angiotensin-converting enzyme (ACE) inhibitor perindopril and the diuretic indapamide. Most of the patients had high blood pressure, but 20 percent had normal blood pressure -- less than 130/80 mm Hg.

After an average follow-up of four years, patients taking the blood pressure-lowering drugs were 21 percent less likely to have kidney disease than those in the placebo group. The researchers also found that kidney function returned to normal among some patients who had early signs of diabetes-related kidney disease before they started taking the drugs.

Even in patients who didn't have high blood pressure, the drug combination reduced the risk of kidney disease.

More research is needed, but these results suggest that patients with type 2 diabetes might be considered for antihypertensive treatment even if they have normal blood pressure, said the authors of the study, which appears in the April issue of the Journal of the American Society of Nephrology.

The researchers noted their study did have important limitations, including the fact that it was an analysis of a previous clinical trail.

"Most of the findings related to early manifestation of kidney disease [albuminuria], and the study was not large enough to assess the impact of the intervention directly on the risk of kidney failure. We could not separate out the impact of the blood pressure-lowering combination used, or prove whether it had any effects beyond its blood pressure-lowering effects," study co-author Vlado Perkovic, of the George Institute for International Health in Sydney, Australia, added in an American Society of Nephrology news release.

More information

The National Kidney Foundation has more about diabetes and kidney disease.

-- Robert Preidt

SOURCE: American Society of Nephrology, news release, Feb. 18, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Two-Drug Combo Fights Brain Tumors
2. Two-Drug Combo Reduces Diabetic Kidney Damage
3. Two-Drug Treatment Didnt Improve Cardiac Arrest Survival Rates
4. Radiation and drug combo helps boost efficacy of lung cancer treatment
5. Aerobic, Weight Training Combo Best Against Diabetes
6. New antibiotic drug combo to speed up treatment of tuberculosis
7. Drug Combo Helps Fight Marfan Syndrome
8. Drug Combo Blocks Pain Without Impairing Movement
9. CPR, Defibrillator Combo Boosts Cardiac Incident Survival
10. Drug Combo Boosts Multiple Myeloma Survival
11. Drug Combos Effective Against Rheumatoid Arthritis
Post Your Comments:
Related Image:
Two-Drug Combo May Lower Diabetics' Kidney Risk
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, ... Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. ... skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World ... with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the ...
(Date:6/24/2016)... Diego, CA (PRWEB) , ... June 24, 2016 , ... ... with the American Cancer Society and the Road To Recovery® program to drive cancer ... to seniors and other adults to ensure the highest quality of life and ongoing ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Grove Investment Group (TGIG), has initiated cultivation and processing operations at its production ... and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... Calif. , June 24, 2016  American Respiratory Labs (ARL), ... is now able to perform sophisticated lung assessments in patients, homes, ... , Inc. Patients are no longer limited to ... EasyOne PRO ® , ARL patients like Jeanne R. of ... in the comfort of her own home. ...
(Date:6/24/2016)... Belgium , June 24, 2016 ... the appointment of Dr. Edward Futcher ... Non-Executive Director, effective June 23, 2016.Dr. Futcher was ... Nominations and Governance Committees.  As a non-executive member ... independent expertise and strategic counsel to VolitionRx in ...
Breaking Medicine Technology: