Navigation Links
Two-Drug Combo May Lower Diabetics' Kidney Risk

A pair of blood pressure medicines helps maintain proper organ function, study suggests

THURSDAY, Feb. 19 (HealthDay News) -- A combination of two blood pressure-lowering drugs reduced the risk of kidney disease by about 20 percent in people with type 2 diabetes, according to researchers who analyzed data from a study that included more than 11,000 patients.

The patients were randomly selected to receive either placebos or a combination of the angiotensin-converting enzyme (ACE) inhibitor perindopril and the diuretic indapamide. Most of the patients had high blood pressure, but 20 percent had normal blood pressure -- less than 130/80 mm Hg.

After an average follow-up of four years, patients taking the blood pressure-lowering drugs were 21 percent less likely to have kidney disease than those in the placebo group. The researchers also found that kidney function returned to normal among some patients who had early signs of diabetes-related kidney disease before they started taking the drugs.

Even in patients who didn't have high blood pressure, the drug combination reduced the risk of kidney disease.

More research is needed, but these results suggest that patients with type 2 diabetes might be considered for antihypertensive treatment even if they have normal blood pressure, said the authors of the study, which appears in the April issue of the Journal of the American Society of Nephrology.

The researchers noted their study did have important limitations, including the fact that it was an analysis of a previous clinical trail.

"Most of the findings related to early manifestation of kidney disease [albuminuria], and the study was not large enough to assess the impact of the intervention directly on the risk of kidney failure. We could not separate out the impact of the blood pressure-lowering combination used, or prove whether it had any effects beyond its blood pressure-lowering effects," study co-author Vlado Perkovic, of the George Institute for International Health in Sydney, Australia, added in an American Society of Nephrology news release.

More information

The National Kidney Foundation has more about diabetes and kidney disease.

-- Robert Preidt

SOURCE: American Society of Nephrology, news release, Feb. 18, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Two-Drug Combo Fights Brain Tumors
2. Two-Drug Combo Reduces Diabetic Kidney Damage
3. Two-Drug Treatment Didnt Improve Cardiac Arrest Survival Rates
4. Radiation and drug combo helps boost efficacy of lung cancer treatment
5. Aerobic, Weight Training Combo Best Against Diabetes
6. New antibiotic drug combo to speed up treatment of tuberculosis
7. Drug Combo Helps Fight Marfan Syndrome
8. Drug Combo Blocks Pain Without Impairing Movement
9. CPR, Defibrillator Combo Boosts Cardiac Incident Survival
10. Drug Combo Boosts Multiple Myeloma Survival
11. Drug Combos Effective Against Rheumatoid Arthritis
Post Your Comments:
Related Image:
Two-Drug Combo May Lower Diabetics' Kidney Risk
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... agency serving communities in the greater Dallas, Miami, and Raleigh regions, is organizing ... fighting to overcome a rare and deadly chromosome abnormality. , After struggling since ...
(Date:10/13/2017)... ... ... The American Board of Family Medicine's (ABFM) Board of Directors has selected ... Dr. James C. Puffer upon his retirement. Dr. Newton will serve in the position ... the end of 2018. Upon assuming the role of President and CEO on January ...
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & ... and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to ... with elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for ... for action towards gender equality at their inaugural Summit in New York City in ... reached a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Cohen Veterans Bioscience and Early Signal Foundation ... and home sensors for real-time monitoring of patients with ... nonprofit organization focused on disruptive health solutions for rare ... system to record and integrate behavioral, cognitive, physiological and ... ...
(Date:9/25/2017)... --  Montrium , an industry leader in powerful ... Trial Master Files & Inspection Readiness Conference ( ... Services has selected eTMF Connect to ... a leading European contract research organization (CRO), will ... enable greater collaboration with sponsors, improve compliance and ...
(Date:9/22/2017)... , Sept. 22, 2017  As the latest Obamacare ... Bill Cassidy (R-LA) and Lindsey Graham ... that the medical device industry is in an odd ... tax, the 2.3% excise tax on medical device sales ... also want covered patients, increased visits and hospital customers ...
Breaking Medicine Technology: