Navigation Links
Two Antibiotics Linked to Liver Injury in Elderly
Date:8/13/2012

MONDAY, Aug. 13 (HealthDay News) -- A new study finds that two antibiotics commonly used to treat respiratory and sinus infections -- moxifloxacin (Avelox) and levofloxacin (Levaquin) -- may boost the risk of severe liver injury in seniors.

The two drugs belong to a class of antibiotics called fluoroquinolones.

For the study, published Aug. 13 in CMAJ (the Canadian Medical Association Journal), Canadian researchers examined the medical records of 144 patients in Ontario who were over 65 and admitted to the hospital to treat liver injury within a month of receiving moxifloxacin or other antibiotics commonly used to treat respiratory infections. The patients had no history of liver disease, and 88 of them died.

"Compared with clarithromycin, moxifloxacin was associated with a more than twofold increased risk of admission to hospital for acute liver injury," the study authors wrote in a journal news release. "Levofloxacin was also associated with a statistically significant but lower risk of hepatotoxicity than moxifloxacin."

However, the risk of liver injury is rare, say the researchers, from Toronto's Institute for Clinical Evaluative Sciences, the University of Toronto and McMaster University in Hamilton, Ontario. Liver problems affect about six of each 100,000 patients treated with the antibiotics, they found.

"Despite recent regulatory warnings regarding the hepatic safety of moxifloxacin, there is a lack of controlled studies supporting the notion that moxifloxacin presents a particular risk relative to other broad-spectrum antibiotic agents and, in particular, to other fluoroquinolones," the authors said. "Although our results require confirmation in other settings, the findings suggest that both moxifloxacin and levofloxacin be considered for regulatory warnings regarding acute liver injury."

While the study found an association between use of these antibiotics and liver injury, it
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Antibiotics Linked to Retinal Detachment Risk
2. Researchers find evidence of banned antibiotics in poultry products
3. Study Finds Antibiotics Best for Appendicitis
4. FDA Seeks to Limit Antibiotics in Animal Feed
5. Timing of antibiotics important in reducing infections after C-section
6. Pesticides May Be Linked to Slightly Smaller Babies, Shorter Pregnancies
7. Pharmacy Robots Linked to Bacterial Contamination of Drugs
8. 2 genetic deletions in human genome linked to the development of aggressive prostate cancer
9. Dental X-Rays May Be Linked to Benign Brain Tumors
10. In Mice, Drug Reverses Symptoms of Condition Linked to Autism
11. Huntingtons Disease Linked to Reduced Cancer Risk in Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Two Antibiotics Linked to Liver Injury in Elderly
(Date:4/17/2014)... WINSTON-SALEM, N.C. April 17, 2014 Meaningful ... from advanced cancer of the abdomen when treated ... HIPEC, according to a first-of-its-size analysis by physicians ... Forest Baptist has the largest reported, single-center experience ... Edward A. Levine, M.D., and analysis of 20 ...
(Date:4/17/2014)... that India,s shocking rates of suicide are highest in ... to tiny smallholdings less than one hectare ... and coffee, that are highly susceptible to global price ... case studies that point to a crisis in key ... the nation,s economy during the 90s. Researchers say that ...
(Date:4/17/2014)... Queen,s University Belfast,s Vice-Chancellor, Professor Patrick Johnston, whose work ... elected as a Fellow of the European Academy of ... is an independent advisory body of highly distinguished oncologists ... and suffering caused by cancer in Europe. , Professor ... Northern Ireland move from the bottom of the UK ...
(Date:4/16/2014)... , STANFORD, Calif. Consider the marvel of the embryo. ... shape and function as they multiply to become the cells ... tissues of the body. , Now, in a feat of ... the complex genetic coding that allows embryonic cells to proliferate ...
(Date:4/16/2014)... 2014) A team that includes scientists from the School ... at San Antonio, Johns Hopkins University and St. Mary,s University ... fungus to infect the body. , The fungal pathogen ... thrush, and is the most common fungal pathogen to infect ...
Breaking Medicine News(10 mins):Health News:20 years of data shows treatment technique improvement for advanced abdominal cancer 2Health News:New evidence of suicide epidemic among India's 'marginalized' farmers 2Health News:New evidence of suicide epidemic among India's 'marginalized' farmers 3Health News:Stanford scientists develop 'playbook' for reverse engineering tissue 2Health News:Stanford scientists develop 'playbook' for reverse engineering tissue 3
... NJResearchers at Rutgers have unlocked some of the mysteries ... the amount of vitamin A present in the maternal ... 28 issue of the Journal of Biological Chemistry. ... protein that facilitates the formation of vitamin A stores ...
... of Dental Experts to Advance ... Knowledge of CCLAD in Dentistry, LIVINGSTON, N.J., Feb. ... recognized leader in,advanced injection technologies, today reported that earlier ... Anesthetic,Delivery (CCLAD) Summit in New Orleans. The Summit welcomed ...
... Hydrogen peroxide and other oxidants cause lung cells to become ... been known that smoking causes lung cancer, but a new ... in cigarette smoke is what actually causes healthy lung cells ... California, Davis, said their findings may help lead to new ...
... LAWRENCE, Mass., Feb. 28 NxStage Medical,Inc. ... Emil Paganini, MD, formerly,Section Head of Dialysis ... has joined the company as Critical Care ... for corporate clinical,scientific and educational initiatives to ...
... Director General Jean-Jacques Dordain and European Commission Director General for ... agreement which establishes the allocation of an EC budget of ... of the GMES Space Component (GSC). , This will be ... 205 million for Segment 2 of the GSC programme. Segment ...
... LOS ANGELES, Feb. 28 /PRNewswire/-- Envision,Productions has teamed ... medical,science breakthrough technique known as The Sign Chi ... campaign, 30 minute infomercial,and strategic media placement, Dr. ... our everyday lives., Dr. Anne Borik, once ...
Cached Medicine News:Health News:Rutgers researchers unlock mysteries of vitamin A metabolism during embryonic development 2Health News:Rutgers researchers unlock mysteries of vitamin A metabolism during embryonic development 3Health News:Milestone Scientific Hosts First International Computer-Controlled Local Anesthetic Delivery (CCLAD) Summit 2Health News:Milestone Scientific Hosts First International Computer-Controlled Local Anesthetic Delivery (CCLAD) Summit 3Health News:Milestone Scientific Hosts First International Computer-Controlled Local Anesthetic Delivery (CCLAD) Summit 4Health News:Milestone Scientific Hosts First International Computer-Controlled Local Anesthetic Delivery (CCLAD) Summit 5Health News:Scientists Find Cancer Culprits in Cigarette Smoke 2Health News:Emil Paganini, MD, Joins NxStage(R) as Critical Care Medical Advisor 2Health News:Emil Paganini, MD, Joins NxStage(R) as Critical Care Medical Advisor 3Health News:Space sentinels: New 'tools' in space to improve European environment and security policies 2Health News:Space sentinels: New 'tools' in space to improve European environment and security policies 3Health News:Groundbreaking Sign Chi Do Stress Management System Introduced by Dr. Anne Borik Now Available to the Public 2
(Date:1/15/2014)... Jan. 15, 2014 /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic ... . (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) ... policy support, China,s orthopedic instrument ... total market size rising from 3.28 billion yuan in ...
(Date:1/15/2014)...  Novation, the leading health care supply chain expertise, analytics ... (VAR) national contracts that expand its portfolio to provide ... costs. These include manufacturer product and service agreements, as ... ongoing IT consulting support. New Novation ...
(Date:1/15/2014)... 15, 2014 BreedIT Corp (OTC: BRDT), ... distributor of highly sophisticated agro-breeding solutions for plant breeders ... the Company,s board of directors appointed chemistry and pharmaceutical ... new member of the board. From 1975 ...
Breaking Medicine Technology:Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3
... PHILADELPHIA, Oct. 26 Pleio Health Support Systems, ... GoodStart(TM) medication adherence program. Retrospective analysis of ... a chronic cardiovascular medication between May 2008 and ... highly significant impact on medication adherence, resulting in ...
... Genomma Lab Internacional, S.A.B. de C.V. (BMV: LAB) ("Genomma ... quarter ended September 30, 2009. All figures included herein ... in nominal Mexican pesos. Also, the following consolidated figures show ... Mexican GAAP. , 3Q09 Highlights (vs. 3Q08) , ...
Cached Medicine Technology:Patients who Participated in Pleio GoodStart(TM) Refilled 30% Sooner and 40% More, Averaging 2 Additional Rx Refills per Patient 2Genomma Lab Internacional Announces Third Quarter 2009 Results 2Genomma Lab Internacional Announces Third Quarter 2009 Results 3
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
Medicine Products: