Navigation Links
Twins Study Points to Environmental Cause for MS
Date:4/28/2010

With near-identical DNA, why does one twin get the illness while the other does not?

WEDNESDAY, April 28 (HealthDay News) -- Genetics can't seem to explain why one twin would have multiple sclerosis while an identical twin doesn't, a new study finds.

That leaves scientists still stumped as to what causes multiple sclerosis (MS), although it's clearer than ever that environmental factors play a major role.

"We found that these twins had a lot of genetic risk factors for MS and yet the twins were born on the same day in the same family, grew up together, ate the same food, went to the same schools and they [both] had that predisposition, that set of risk factors. But, one developed the disease and one didn't," said study senior author Dr. Stephen Kingsmore.

"This points to some environmental trigger that protected one of the twins or triggered the disease in one of the twin members," added Kingsmore, who is CEO of the National Center for Genome Resources in Santa Fe, NM.

According to the researchers, this was the first use of a genome-wide analysis to study an autoimmune disease in identical twins.

The findings are published in the April 29 issue of Nature.

Little is known about the causes of MS, an autoimmune disorder in which the body attacks the myelin sheath that protects the nerve fibers of the central nervous system. It can cause vision problems, muscle weakness, and thinking and memory difficulties.

Genes -- not one, but many -- clearly play some kind of role, as do as-yet-unidentified environmental factors.

One mystery surrounding the disease has been why 30 to 40 percent of identical twin pairs develop MS, while the rest don't.

"What makes up the other 60 or 70 percent?" asked Patricia O'Looney, vice president of biomedical research at the National Multiple Sclerosis Society in New York City.

The researchers set out to see if ge
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. For Valentine's Day, Lifestyle Correspondent and Her Two Sets of Twins Show a Little Love Where Its Needed the Most
2. Twins Provide Clues to Lupus
3. Fibromyalgia affects mental health of those diagnosed and their spouses, study finds
4. Children's Rights Group Agrees with New Study: Infant Circumcision Causes 100 Deaths Each Year in US
5. Cell study finds receptor can fight tamoxifen-resistant breast cancer cells
6. Study examines global availability of treatment involving transplantation of blood stem cells
7. Study finds that drugs used for treatment of influenza in pregnancy appear to be safe
8. Comparative-effectiveness study confirms new treatment for diabetic macular edema
9. CureTogether Announces Online Autism Treatment Study
10. LA BioMed awarded research grant to study HIV prevention gel
11. Study Makes Strides in Understanding Ovarian Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2015)... April 8th, 2015, saw the transformation of ... “RockNRolla Movie Awards” EcoLuxe Lounge, a daylong event, sponsored ... the world’s top providers of ecologically sound and social ... Debbie Durkin, Los Angeles’ leading producer of sustainable product ... a premier red carpet event that makes appearances at ...
(Date:6/2/2015)... On Wednesday, May 27, 2015, professional driver, ... top speed of 207.9 mph. In the process, Hennessey’s ... the 200 mph mark. Jay Leno was on hand ... of Jay Leno’s Garage, which will air on CNBC later ... mile high speed oval at the Continental Tire Proving Grounds ...
(Date:6/2/2015)... Residents looking for a new dentist in ... convenient location now that Coast Dental Kissimmee is moving ... Irlo Bronson Memorial Highway, Suite C-106, Kissimmee, FL 34744. ... away from its original location, and features a beautiful, ... with digital intraoral and panoramic x-ray system and laser ...
(Date:6/2/2015)... Phoenix, AZ (PRWEB) June 02, 2015 The ... encouraged viewers to watch the station’s 6:00 a.m. Good Morning ... be entered on the station’s Facebook page. , ... other code-entering participants. She plans to apply the monthly ... months. Allen, a stay-at-home mom, expressed her surprise and ...
(Date:6/2/2015)... June 02, 2015 The term “Augmented ... generated imagery overlaid on the real world. Since then ... Visualization, which displays a map of the vasculature on ... growth in adoption. , AccuVein, the leader in vein ... year growth rate and such widespread adoption of its ...
Breaking Medicine News(10 mins):Health News:Choices Recovery South Bend Discusses Addiction With Rising Hollywood Star Ben Stillwell 2Health News:774 HP Hennessey Mustang Tested to 207.9 mph 2Health News:Coast Dental Office Opening In Kissimmee with Expanded Technology 2Health News:Scottsdale Resident Named $12,000 Prize Winner- Arizona Central and KTVK 3TV Phoenix Partner in Mortgage Giveaway Contest 2Health News:Vein Visualization Emerges as Premier Augmented Reality Application 2
... July 2 Interleukin Genetics, Inc. (NYSE Amex: ILI ... agreement to sell the Alan James Group assets of its subsidiary ... Corporation, for approximately $4.6 million in cash. The transaction was completed ... , "While the Alan James Group business saw an increase ...
... ... has been an invasive procedure involving painful blood tests. ,However, that has changed thanks to ... oral fluids. , ... CA (Vocus) July 2, 2009 -- Until now, determining a person’s lead exposure has been ...
... ... the right type of support, knowledge, and tools are critical to meeting breastfeeding goals. A ... decades. The Freemie system is a hands-free and concealable breast milk collection system ... ...
... In a recent ... prevalence of obstructive sleep apnea (OSA) may be higher than expected in suburban dental practices. ... (Vocus) July 2, 2009 -- In a ... the prevalence of obstructive sleep apnea (OSA) may be higher than expected in suburban ...
... conjunction with yesterday,s FDA approval of AMAG Pharmaceuticals, Feraheme (ferumoxytol), ... Feraheme , a syndicated report series that will track the ... new IV Iron product approved to treat iron deficiency anemia ... on dialysis. Surveys will be fielded at one month, ...
... MCLEAN, Va., July 1 On Thursday June 18th, 2009, ... by presenting him with the Association,s 2009 Achievement Award. ... must demonstrate significant professional and/or personal contributions to AOPO. ... because of his tireless efforts to ensure data accuracy and ...
Cached Medicine News:Health News:Interleukin Genetics Announces Strategic Divestment of Alan James Group 2Health News:LeadConfirm Professional Now Available at Drugstore.com - The First Oral Based Lead Test, Makes Getting the Lead Out Easier 2Health News:LeadConfirm Professional Now Available at Drugstore.com - The First Oral Based Lead Test, Makes Getting the Lead Out Easier 3Health News:LeadConfirm Professional Now Available at Drugstore.com - The First Oral Based Lead Test, Makes Getting the Lead Out Easier 4Health News:Working Moms Find Freedom to Use Breast Pumps Where They Want, When They Want 2Health News:High Incidence of Obstructive Sleep Apnea in Suburban Dental Practices 2Health News:BioTrends Announces a New Syndicated Report Series, LaunchTrends(TM): Feraheme 2Health News:Kent Holloway of Ohio Receives Achievement Award From Organ Donation Association 2
(Date:6/3/2015)... DALLAS , June 3, 2015  VA ... today with the successful patient implant of vBloc, a technology-based, ... vBloc is a pacemaker-like implant called the Maestro® ... signals or transmission of messages involving food intake ... Maestro System is wireless and customizable to meet ...
(Date:6/3/2015)... aTyr Pharma, Inc. (NASDAQ: LIFE ), a ... therapeutics to address rare diseases, today announced the Company,s participation ... Conference to be held at the Four Seasons Hotel in ... John Mendlein , aTyr,s CEO and Executive Chairman, ... 9:20 a.m. CT on Wednesday, June 10, 2015. The presentation ...
(Date:6/3/2015)... MENLO PARK, Calif. , June 3, 2015 ... novel small molecule drugs for cardiovascular diseases, today ... MPH, has been appointed Chief Executive Officer, effective ... of experience in global, high-growth enterprises, with a ... the improvement of human health. With expertise that ...
Breaking Medicine Technology:VA North Texas First VA in the Country to Perform vBloc Implant, a Cutting-Edge Weight Loss Therapy 2VA North Texas First VA in the Country to Perform vBloc Implant, a Cutting-Edge Weight Loss Therapy 3Armetheon Names Dr. Sanjay Kakkar as Chief Executive Officer 2Armetheon Names Dr. Sanjay Kakkar as Chief Executive Officer 3Armetheon Names Dr. Sanjay Kakkar as Chief Executive Officer 4
... This compact system provides an ... preparation in the laboratory, satellite lab ... proven HEMA-TEK staining method with wedge-smear ... delivers complete standardization in a safe ...
It is a cardio-pulmonary exercise testing device....
... has digitally-controlled drive system which eliminates ... can wear out. There are no ... and fewer drive belts - resulting ... It can carry weights up to ...
... systems feature our internationally-acclaimed algorithm that ... algorithm has a proven record for ... situations; and it's just one of ... recognized market leader in the stress ...
Medicine Products: