Navigation Links
Twins Provide Clues to Lupus
Date:12/28/2009

Study shows lifestyle differences could explain why only one sibling affected

MONDAY, Dec. 28 (HealthDay News) -- Cellular changes caused by environmental factors such as diet and chemical exposure may play a role in the autoimmune disease lupus, a new study suggests.

American and Spanish researchers compared the DNA of identical twins to look for epigenetic modifications (cellular changes that can influence the expression of genes) in healthy twins and twins with lupus.

Twins with lupus were found to have widespread changes in a specific epigenetic modification called DNA methylation in a significant number of genes. Many of those genes are related to multiple immune system functions.

The findings were published online in the journal Genome Research.

"Our study suggests that the effect of the environment or differences in lifestyle may leave a molecular mark in key genes for immune function that contributes to the differential onset of [lupus] in twins," senior author Dr. Esteban Ballestar said in a news release.

Further research into the role that DNA methylation changes play in autoimmune diseases may lead to new treatments, he added.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about lupus.



-- Robert Preidt



SOURCE: Cold Spring Harbor Laboratory, news release, December 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Overweight Twins Battle the Bulge and Gain A New Lease on Life in National Body Challenge: Twins Edition on Discovery Health
2. Twins study shows genetic basis for face and place recognition
3. Congenital heart defects increasing among IVF twins
4. Formerly Conjoined Twins Leave Packard Childrens Hospital; Heading Home to Costa Rica
5. Baby Madness is Sweeping the Nation! Forty Sets of Twins and Triplets Hit the Court in Discovery Healths BABY MADNESS: MULTIPLES
6. Parents of twins report more mental health symptoms than parents of singletons
7. Uterus Size May Predict Risk for Premature Twins After IVF
8. Vaginal/Caesarean combo delivery of twins safe, UT Southwestern-led research finds
9. Twins Pitcher Glen Perkins Kicks Off 7th Anniversary of Fitness Program in MPS
10. Conjoined Twins Separated by Surgical Team at Childrens Hospital of Pittsburgh of UPMC During Complex, 24-Hour Procedure
11. Discover the Deadly Toxic Twins: Hydrogen Cyanide and Carbon Monoxide
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... December 02, 2016 , ... The annual time frame to change Medicare health ... is ending December 7th. Currently-enrolled Medicare beneficiaries who are looking to switch from their ... D) need to make changes during this period order for their new policy to ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... More than ... and while 84 percent of parents report speaking with their child about sex related ... sexually transmitted diseases. , Mediaplanet is proud to announce the launch of its second ...
(Date:12/2/2016)... ... December 02, 2016 , ... Sourced from the Isbre Springs beneath the 5,000 ... unmatched natural purity of just 6 ppm TDS (Total Dissolved Solids) in addition to ... been available in several ShopRite and FoodTown stores in NJ and received rave comments ...
(Date:12/2/2016)... Miami, FL (PRWEB) , ... December 02, 2016 ... ... over 5,100 hot meals to needy individuals and families from eight different sites ... Florida on Thanksgiving Day. Over 1,000 volunteers worked very hard on Thanksgiving morning ...
(Date:11/30/2016)... , ... November 30, 2016 , ... ... they now offer a comprehensive in-house dental plan for all patients. Understanding that ... a plan that gives patients a number of perks, including discounts on many ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... YORK , December 2, 2016 ... Braces & Support) is Expected to Gain a Significant Market ... to Orthopedic Ailments  ... , According to ... Study on Medical Implants Sterile Packaging: Clamshell Product Type Segment ...
(Date:12/2/2016)... On Thursday, the NASDAQ Composite and ... the Dow Jones Industrial Average managed to stay in green. ... which prompted Stock-callers this morning to look at the performances ... NUVA ), Smith & Nephew PLC (NYSE: SNN ... Cesca Therapeutics Inc. (NASDAQ: KOOL ). You can ...
(Date:12/2/2016)... -- The concept of rare diseases and the idea that ... has been taking shape in Europe ... initiatives related to orphan medicinal products have been emerging at ... states individually. Many member states in the EU have led ... medicinal products, the result of which took the shape of ...
Breaking Medicine Technology: