Navigation Links
Twins Provide Clues to Lupus
Date:12/28/2009

Study shows lifestyle differences could explain why only one sibling affected

MONDAY, Dec. 28 (HealthDay News) -- Cellular changes caused by environmental factors such as diet and chemical exposure may play a role in the autoimmune disease lupus, a new study suggests.

American and Spanish researchers compared the DNA of identical twins to look for epigenetic modifications (cellular changes that can influence the expression of genes) in healthy twins and twins with lupus.

Twins with lupus were found to have widespread changes in a specific epigenetic modification called DNA methylation in a significant number of genes. Many of those genes are related to multiple immune system functions.

The findings were published online in the journal Genome Research.

"Our study suggests that the effect of the environment or differences in lifestyle may leave a molecular mark in key genes for immune function that contributes to the differential onset of [lupus] in twins," senior author Dr. Esteban Ballestar said in a news release.

Further research into the role that DNA methylation changes play in autoimmune diseases may lead to new treatments, he added.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about lupus.



-- Robert Preidt



SOURCE: Cold Spring Harbor Laboratory, news release, December 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Overweight Twins Battle the Bulge and Gain A New Lease on Life in National Body Challenge: Twins Edition on Discovery Health
2. Twins study shows genetic basis for face and place recognition
3. Congenital heart defects increasing among IVF twins
4. Formerly Conjoined Twins Leave Packard Childrens Hospital; Heading Home to Costa Rica
5. Baby Madness is Sweeping the Nation! Forty Sets of Twins and Triplets Hit the Court in Discovery Healths BABY MADNESS: MULTIPLES
6. Parents of twins report more mental health symptoms than parents of singletons
7. Uterus Size May Predict Risk for Premature Twins After IVF
8. Vaginal/Caesarean combo delivery of twins safe, UT Southwestern-led research finds
9. Twins Pitcher Glen Perkins Kicks Off 7th Anniversary of Fitness Program in MPS
10. Conjoined Twins Separated by Surgical Team at Childrens Hospital of Pittsburgh of UPMC During Complex, 24-Hour Procedure
11. Discover the Deadly Toxic Twins: Hydrogen Cyanide and Carbon Monoxide
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Dr. Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile ... orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can ...
(Date:6/24/2016)... ... 24, 2016 , ... The Haute Beauty Network, affiliated with ... as a prominent plastic surgeon and the network’s newest partner. , Dr. ... handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands by ...
(Date:6/24/2016)... MD (PRWEB) , ... June 24, 2016 , ... ... protocols for human induced pluripotent stem (iPS) cells and other difficult to transfect ... G9™ Cloning Medium. The PluriQ™ G9™ Gene Editing System is a ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
(Date:6/23/2016)... , June 23, 2016 The vast majority ... outpatient dialysis facility.  Treatments are usually 3 times a ... per visit, including travel time, equipment preparation and wait ... but especially grueling for patients who are elderly and ... skilled nursing and rehabilitation centers for some duration of ...
Breaking Medicine Technology: