Navigation Links
Twins Provide Clues to Lupus
Date:12/28/2009

Study shows lifestyle differences could explain why only one sibling affected

MONDAY, Dec. 28 (HealthDay News) -- Cellular changes caused by environmental factors such as diet and chemical exposure may play a role in the autoimmune disease lupus, a new study suggests.

American and Spanish researchers compared the DNA of identical twins to look for epigenetic modifications (cellular changes that can influence the expression of genes) in healthy twins and twins with lupus.

Twins with lupus were found to have widespread changes in a specific epigenetic modification called DNA methylation in a significant number of genes. Many of those genes are related to multiple immune system functions.

The findings were published online in the journal Genome Research.

"Our study suggests that the effect of the environment or differences in lifestyle may leave a molecular mark in key genes for immune function that contributes to the differential onset of [lupus] in twins," senior author Dr. Esteban Ballestar said in a news release.

Further research into the role that DNA methylation changes play in autoimmune diseases may lead to new treatments, he added.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about lupus.



-- Robert Preidt



SOURCE: Cold Spring Harbor Laboratory, news release, December 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Overweight Twins Battle the Bulge and Gain A New Lease on Life in National Body Challenge: Twins Edition on Discovery Health
2. Twins study shows genetic basis for face and place recognition
3. Congenital heart defects increasing among IVF twins
4. Formerly Conjoined Twins Leave Packard Childrens Hospital; Heading Home to Costa Rica
5. Baby Madness is Sweeping the Nation! Forty Sets of Twins and Triplets Hit the Court in Discovery Healths BABY MADNESS: MULTIPLES
6. Parents of twins report more mental health symptoms than parents of singletons
7. Uterus Size May Predict Risk for Premature Twins After IVF
8. Vaginal/Caesarean combo delivery of twins safe, UT Southwestern-led research finds
9. Twins Pitcher Glen Perkins Kicks Off 7th Anniversary of Fitness Program in MPS
10. Conjoined Twins Separated by Surgical Team at Childrens Hospital of Pittsburgh of UPMC During Complex, 24-Hour Procedure
11. Discover the Deadly Toxic Twins: Hydrogen Cyanide and Carbon Monoxide
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Little Rock, AR (PRWEB) , ... October 13, ... ... owned firm with locations throughout Arkansas that offers insurance and financial preparation services, ... to benefit the Rock City Rescue organization. , Rock City Rescue is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health and Nutrition ... the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD market ... can be easily incorporated into liquid products, while reducing costs to end users. , ...
(Date:10/13/2017)... ... ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to host ... items from across the nation, this holiday-themed event will raise funds and awareness for ... The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 p.m.) ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
(Date:10/12/2017)... ... 12, 2017 , ... Planet Fitness, one of the largest and fastest growing ... open a flagship location in Covington, LA at 401 N. U.S. Highway 190, in ... to Office Depot in the Holiday Square shopping center. Its location allows it to ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Sept. 28, 2017 Hill-Rom Holdings, Inc. (NYSE: ... conference call and webcast on Friday, November 3, 2017, ... and ending at approximately 8:30 a.m. (CDT) / 9:30 ... company,s 2017 financial performance and guidance for 2018, Hill-Rom ... to enhance operational performance, and long-range financial outlook through ...
(Date:9/27/2017)... NEW YORK , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: ... data solutions, today announced that its MyDario product is expected to appear ... listings for when The Dr. Oz Show airs in your area: ... The nine-time Emmy award-winning, The ... ...
(Date:9/23/2017)... , Sept. 22, 2017 Janssen Biotech, Inc. ... response letter from the U.S. Food and Drug Administration ... of sirukumab for the treatment of moderately to severely ... additional clinical data are needed to further evaluate the ... severely active RA. ...
Breaking Medicine Technology: