Navigation Links
'Twinkle' eye test could improve AMD diagnosis

Scientists at UCL (University College London) have developed a more reliable test for detecting vision loss in people with age-related macular disease (AMD), the leading cause of blindness in the UK and US. The method, which centres on a visual illusion, could lead to earlier self-diagnosis of sight deterioration encouraging patients to access medical assistance earlier on and potentially delay loss of vision.

Recent developments in the treatment of AMD mean that vision can be retained in some people with the injection of drugs into the eye, as long as they present to an eye clinic soon after the development of symptoms. These advances mean that accurate diagnosis is increasingly crucial in delaying sight-loss.

The new test, described in the current issue of PLoS ONE, relies on a visual illusion known as the twinkle after-effect, where a moving pattern can be induced in regions of the eye which have vision loss. Previously, this illusion has been demonstrated in normally sighted subjects, by using artificial scotoma (a way of blocking vision in a specific area). This is the first time it has been translated to people with eye disease and the results indicate it could be a powerful diagnostic tool.

Dr Michael Crossland, UCL Institute of Ophthalmology, is one of the researchers involved in this study. He explained: At present, people identified as being at risk of AMD are given a grid chart to observe on a daily basis, and are instructed to attend hospital if they notice any new distortion on this chart.

However, as many as 1 in 2 people will not be able to detect their vision loss using this chart, as the brain fills-in the missing information and perceives the chart as normal, when they actually should see distortion.

The initial data on our test indicates that it is quick, accurate and resistant to the effects of filling-in.

Dr Peter Bex from Harvard Medical School, a co-author on the paper, said: The quality of the results from this very simple test is similar to those obtained with high-tech equipment currently only available in certain specialist clinics or research centres.

Dr Crossland added: At present our test still relies on specialist hardware and software and has only been tried on people with established macular disease. Our aim is that we can adapt this system so that people can have a simple test to check their own vision at home. This will ensure they come to the hospital or see a specialist in time for any possible treatment, giving them the very best chance of delaying the onset of AMD and preserving their vision. Obviously these advances will take some time, so for now the best thing people can do is to ensure they check their vision regularly by the means advised by their specialist.


Contact: Ruth Metcalfe
University College London

Related medicine news :

1. Virus Level could Predict Cervical Cancer Risk
2. Lean Protein Could Be Key to Obesity Drugs
3. Nasal Spray Could Take Drugs Direct to Brain.
4. Beware of the oral patch! It could be cancer!!!
5. Low Birth Weight infants could have Problems in the Future
6. False beliefs could cost cancer patients their lives
7. Oxygen Usage During Exercise Could Indicate Heart Problems
8. Prozac miracle could end in disaster
9. Wonder drug - could end in disaster
10. Pollution could be a risk
11. Fright could be more harmful
Post Your Comments:
(Date:11/27/2015)... Angeles, CA (PRWEB) , ... November 27, 2015 , ... ... conversation at the recent 2015 American Dental Association meeting in Washington D.C. revolved around ... help protect a patient’s overall health. The talk stressed the link between periodontal disease ...
(Date:11/27/2015)... ... 27, 2015 , ... An inventor, from Hopkinsville, Ky., thought ... at home, so he invented the patent-pending ELECTRONIC M.D. , The ELECTRONIC M.D. ... doing so, it could help to prevent potential overdose situations. As a result, ...
(Date:11/27/2015)... ... November 27, 2015 , ... MPWH, the No.1 Herpes-only dating community in the world, revealed ... 1-1 ). More than 3.7 billion people under the age of 50 – or ... to WHO's first global estimates of HSV-1 infection . , "The data shocks us ...
(Date:11/27/2015)... ... November 27, 2015 , ... Keeping ... platform for mental health and wellness consultation, has collaborated with a leading web-based ... the knowledge gap experienced by parents and bring advice from parenting experts within ...
(Date:11/27/2015)... ... November 27, 2015 , ... Indosoft ... announces the incorporation of Asterisk 11 LTS (Long Term Support) into its Q-Suite ... LTS brings Q-Suite 5.10 up-to-date with a version of Asterisk that will receive ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... N.C. , Nov. 25, 2015 ... the planned investment of at least $15.8  Million ... Wilmington, NC . The expansion ... capacity to meet the growing demands of the ... site expansion will provide up to ...
(Date:11/25/2015)... , Nov. 25, 2015  Henry Schein, Inc., the ... to office-based dental, medical and animal health practitioners, will ... the Henry Schein ConnectDental® Pavilion , which brings ... of open solutions designed to help any practice or ... here for a schedule of experts appearing at ...
(Date:11/25/2015)... 25, 2015  Trovagene, Inc. (NASDAQ: TROV ), ... Chief Executive Officer Antonius Schuh, Ph.D., is scheduled to ... Annual Piper Jaffray Healthcare Conference. th ... Palace Hotel in New York ... Mr. Schuh will be available for one-on-one meetings during ...
Breaking Medicine Technology: