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Twenty New Abstracts on Oral Xeloda(R) (capecitabine) Featured at the 31st San Antonio Breast Cancer Symposium
Date:12/9/2008

NUTLEY, N.J., Dec. 9 /PRNewswire/ -- Roche announced today that a total of 20 U.S. and global abstracts involving its oral chemotherapy Xeloda(R) (capecitabine) have been accepted for presentation at the 2008 San Antonio Breast Cancer Symposium (SABCS) in San AntonioDecember 12-14, including a late-breaking study in early breast cancer to be presented on Sunday, December 14, by the Finnish Breast Cancer Group.

Two U.S. abstracts to be presented at the meeting compare the impact of chemotherapy-related costs on direct medical expenditures among patients with metastatic breast cancer who were treated with oral Xeloda monotherapy compared with vinorelbine monotherapy in one study or gemcitabine monotherapy in the other. The data showed that metastatic breast cancer patients treated with Xeloda monotherapy had statistically significant lower total health care costs than patients treated with vinorelbine monotherapy or gemcitabine monotherapy.

The third U.S. abstract demonstrated the accuracy of using p53 gene mutations to predict short-term clinical and pathological responses in women with operable early stage breast cancer in the Phase II XeNA (Xeloda in NeoAdjuvant) trial. The fourth U.S. abstract compares the characteristics of and survival among North Carolina metastatic breast cancer patients treated with Xeloda or taxane monotherapy.

-- Dec. 14, 7:00 to 9:00 a.m., [Poster No. 6107], Capecitabine is associated with lower chemotherapy-related expenditures than those associated with vinorelbine in women with metastatic breast cancer (Lead Author: Michael Lee)

-- Dec. 14, 7:00 to 9:00 a.m., [Poster No. 6108], Capecitabine is associated with lower chemotherapy-related expenditures than those associated with gemcitabine in women with metastatic breast cancer (Lead Author: Michael Lee)

-- Dec. 14, 7:00 to 9:00 a.m., [Poster No. 6047], p53 mutational status, but not immunohist
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SOURCE Roche
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