Navigation Links
Turning agents of disease into tools for health and better living
Date:6/30/2011

Viruses that attack plants, insects, mammals and bacteria are proving effective platforms for delivering medicines and imaging chemicals to specific cells in the body, as building blocks for tiny battery electrodes and computer data storage devices, and other nanotechnologies.

The burst of research over the last two decades, with explanations aimed at undergraduate and graduate college students and scientists within and outside the field, is described in a new book written by Nicole Steinmetz, an assistant professor of biomedical engineering at Case Western Reserve University, and Marianne Manchester, a professor of pharmacy and pharmaceutical sciences at the University of California at San Diego.

The textbook, Viral Nanoparticles: Tools for Materials Science and Biomedicine, summarizes the work done by engineers, chemists, physicists, materials scientists, medical researchers and others; the viruses used and the applications. The book is available now.

"The field is rapidly expanding, with people from more and more backgrounds coming into it," said Steinmetz, who has been manipulating viruses since she was an undergraduate researcher. Earlier in her career she created multilayered thin film arrays made of multiple 3-dimensional viral nanoparticles for use in sensors or nanoelectronics, but is now focusing on the application of plant viruses for medical use, such as cancer detection and imaging and targeted drug delivery.

Manchester has long specialized in the interface between viral nanoparticles and physiologic systems, defining the ways that viruses interact with cell surfaces and organs within the body. "The field is now poised to move forward toward commercial and clinical applications," she said. "The book provides an overview of these challenges and opportunities".

Viruses are finding a wide range of uses in nanoscience and nanotechnology, because of a host of practical traits, she explains. Viruses are already nano-sized 100,000s of times smaller than the width of a human hair. Their structures have been optimized by nature, physically and chemically each unit of the same strain of virus is identical, they're cheap and easy to produce and they easily self-assemble into two-and three-dimensional structures.

The infectious agents are also stable, hardy and biocompatible.

The book details how researchers have mineralized viruses to produce nanowires used in nanoelectronics, and build thin-film micro-arrays. The authors explain how scientists have rendered the infectious agents benign, as well as genetically or chemically altered versions for specific uses.

They tell how they and others have modified the surfaces of viral nanoparticles to link up with targets, such as tumor cells, and modified their interiors to carry medicines, fluorescent chemicals used in imaging applications, or other cargo.


'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

Related medicine news :

1. Sniffing out lymphoma by turning dogs into humans
2. Some women worry too much about breast cancer returning, U-M study finds
3. Innovative virtual reality exposure therapy shows promise for returning troops
4. Turning off stress
5. Gene identified that prevents stem cells from turning cancerous
6. Microbicide trial results a turning point for HIV prevention, says team testing same gel
7. Turning back the cellular clock
8. Study Probes Causes of Anger in Returning U.S. Soldiers
9. Turning a painkiller into a cancer killer
10. Holistic Management and Allan Savory Win the 2010 Buckminster Fuller Award for Turning Deserts into Thriving Grasslands and Combating Climate Change.
11. Parents of Autistic Children Turning to Alternative Treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills ... specialty vendors and unique items from across the nation, this holiday-themed event will raise ... offered by the VNA. The boutique will be open Saturday, November 4 (10:00 ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
(Date:10/12/2017)... ... ... Planet Fitness, one of the largest and fastest growing franchisors and operators ... location in Covington, LA at 401 N. U.S. Highway 190, in January of 2018. ... in the Holiday Square shopping center. Its location allows it to serve both Covington ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... system that we intend to develop to enable prevention of a major side ... severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned ... Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness ... on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... Sept. 25, 2017   Montrium , an ... solutions, today—from the IQPC Trial Master Files & ... NL)—announced that EastHORN Clinical Services has selected ... and TMF management. EastHORN, a leading European contract ... to increase transparency to enable greater collaboration with ...
(Date:9/22/2017)... -- AVACEN Medical (AVACEN) announced that its CE-Marked AVACEN ... with the widespread pain associated with fibromyalgia in the ... Essex, England commented, "I had difficulty ... sleep at all, tremendous pain, with every movement sending ... AVACEN 100] enough, how this has and is helping ...
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
Breaking Medicine Technology: