Navigation Links
Turning Alzheimer's fuzzy signals into high definition
Date:5/7/2013

Scientists at the Virginia Tech Carilion Research Institute have discovered how the predominant class of Alzheimer's pharmaceuticals might sharpen the brain's performance

One factor even more important than the size of a television screen is the quality of the signal it displays. Having a life-sized projection of Harry Potter dodging a Bludger in a Quidditch match is of little use if the details are lost to pixilation.

The importance of transmitting clear signals, however, is not relegated to the airwaves. The same creed applies to the electrical impulses navigating a human brain. Now, new research has shown that one of the few drugs approved for the treatment of Alzheimer's disease helps patients by clearing up the signals coming in from the outside world.

The discovery was made by a team of researchers led by Rosalyn Moran, an assistant professor at the Virginia Tech Carilion Research Institute. Her study indicates that cholinesterase inhibitors a class of drugs that stop the breakdown of the neurotransmitter acetylcholine allow signals to enter the brain with more precision and less background noise.

"Increasing the levels of acetylcholine appears to turn your fuzzy, old analog TV signal into a shiny, new, high-definition one," said Moran, who holds an appointment as an assistant professor in the Virginia Tech College of Engineering. "And the drug does this in the sensory cortices. These are the workhorses of the brain, the gatekeepers, not the more sophisticated processing regions such as the prefrontal cortex where one may have expected the drugs to have their most prominent effect."

Alzheimer's disease affects more than 35 million people worldwide a number expected to
'/>"/>

Contact: Paula Byron
paulabyron@vt.edu
540-526-2027
Virginia Tech
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Coffee may help prevent breast cancer returning, study finds
2. Anesthesia increases success rates of turning breech babies, reduces delivery costs
3. As Economy Rebounds, More Folks Try Turning Back Hands of Time
4. Turning repulsive feelings into desires
5. Turning Tragedy Into Hope for Others With Spinal Cord Injury
6. Inside a machine for turning coffee into science
7. Yumi Media Commented on an Article That Says Turning Vegetarian Helps You Discover New Recipes
8. AuDNet Pushes for Professional Hearing Tests for All Troops Returning from the Middle East.
9. Quorn Foods Inc. Releases a Statement Regarding the News of Meat Eaters Turning to Meatless Meals When Dining
10. 1 in 4 in U.S. Starts Drinking Before Turning 21: Report
11. Time Change Means Turning Clocks Back on Sunday
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... variant specifically associated with the risk of a ... cent of all breast cancer cases. , The ... called invasive lobular carcinoma, gives researchers important clues ... of breast cancer, which can be missed through ... the journal PloS Genetics , was co-led ...
(Date:4/17/2014)... In the April issue of Experimental Biology ... by Drs. Rex Gaskins and Paul Kenis in ... campus of the University of Illinois Urbana-Champaign describe ... reduction-oxidation reactions underlie a variety of cell functions ... to these crucial roles in regulating normal cellular ...
(Date:4/17/2014)... Pediatrician-in-Chief Jon McCullers, MD, was recently invited to ... Nature Reviews Microbiology , one of the ... world-renowned infectious disease specialist, and chair of the ... Health Science Center, analyzed the epidemiology and microbiology ... pandemics, as well as more recent 2009 novel ...
(Date:4/17/2014)... million older Americans suffer from depression, often brought on ... research a project that followed the lives of ... found that Internet use among the elderly can reduce ... , "That,s a very strong effect," said Shelia Cotten, ... and media who led the project. "And it all ...
(Date:4/17/2014)... of Medicine (BUSM) have discovered that the anti-seizure ... model. The findings, reported in the American ... lead to more effective treatments for alcoholism. , ... leading causes of illness and death in the ... limiting the productivity of workers and necessitating huge ...
Breaking Medicine News(10 mins):Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2Health News:Internet use can help ward off depression among elderly 2Health News:BUSM researchers find anti-seizure drug may reduce alcohol consumption 2
... (HealthDay News) -- Married men or those in common-law relationships ... are single, divorced or widowed, according to a new study ... receiving medical care sooner, married men are more likely to ... study,s findings could help inform the public about why prompt ...
... of the University of Granada and Edimbourgh have developed ... might improve significantly chemotherapy, as it has not cause ... encapsulation of a catalyst (palladium) into microspheres, to synthesize ... avoiding any toxicity. This system captures palladium within its ...
... from the Hebrew University have identified the molecular basis for ... this research have just been published in the journal ... genetic information required for building the proteins of the cell. ... in the cell function. These changes can lead to defects ...
... A group of French scientists (from the Unit of ... Research, Bobigny, France; the French Institute for Prevention and ... Cancer Institute) have published a paper in the ... guidelines for drinking and the relation of alcohol to ...
... the brain,s master circadian clock known as the suprachiasmatic ... rhythmic neural activity begins to decline by middle age. The ... have implications for the large number of older people who ... "Aging has a profound effect on circadian timing," said ...
... By Alan Mozes HealthDay Reporter , ... in the mid-1990s, powerful antiretroviral therapies have radically improved ... world. Now, research suggests that when made ... effective for African patients. The finding stems from ...
Cached Medicine News:Health News:Married Men Seem to Seek Help for Heart Attacks Sooner 2Health News:A new therapy without side effects could improve dramatically chemotherapy 2Health News:Hebrew U. scientists identify molecular basis for DNA breakage 2Health News:Are drinking guidelines adequate regarding the risk of cancer? 2Health News:Are drinking guidelines adequate regarding the risk of cancer? 3Health News:Study shows new evidence of age-related decline in the brain's master circadian clock 2Health News:Study shows new evidence of age-related decline in the brain's master circadian clock 3Health News:Study shows new evidence of age-related decline in the brain's master circadian clock 4Health News:Study shows new evidence of age-related decline in the brain's master circadian clock 5Health News: Drugs Can Bring HIV-Infected Africans Normal Life Spans 2Health News: Drugs Can Bring HIV-Infected Africans Normal Life Spans 3Health News: Drugs Can Bring HIV-Infected Africans Normal Life Spans 4
(Date:1/15/2014)... 2014 /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument Industry ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) Benefiting ... China,s orthopedic instrument industry has ... size rising from 3.28 billion yuan in 2006 to ...
(Date:1/15/2014)... Jan. 15, 2014 As health officials across the Midwest ... Meijer pharmacies in Michigan will offer ... patients, enabling Meijer pharmacists to administer tests and, in some ... a physician participating in the study. The ...
(Date:1/15/2014)... Corporation (the "Company") (NASDAQ: CLSN ) today ... to purchase an aggregate of approximately $15 million of ... offering, led by a dedicated health care fund. ... these investors pursuant to which the Company agreed to ...
Breaking Medicine Technology:Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3
... (IGF-1) is a polypeptide of 70 amino acids ... of related insulin-like growth factors present in the ... with proinsulin and has a number of biological ... hormone (GH) dependent to a high degree, but ...
...
...
...
Medicine Products: