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Tug of war in the cells
Date:3/19/2008

heavily on the properties and the number of the motors involved. The cell uses these to direct the cargo transport. If a team of motors is pulled harder or faster, the cargo moves in the minus instead of the positive direction or stops.

"The simple and efficient tug-of-war mechanism could be used for the transport in micro-laboratories on chips," relates Melanie Mueller. In the same way as with the biological model, teams of motors can transport certain molecules to specific reaction locations on the chip and then also bring back the reaction product. "Our quantitative tug-of-war theory allows motor properties to be optimized for this purpose," according to Mueller.


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Contact: Melanie J.I. Mueller
mmueller@mpikg.mpg.de
49-331-567-9623
Max-Planck-Gesellschaft
Source:Eurekalert  

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