Navigation Links
Tug of war in the cells
Date:3/19/2008

This release is available in German.

Transport processes in the cells of our body resemble the transport of goods on the roads. Molecular motors, which are special protein molecules, act as trucks. They carry the cellular cargo on piggy-back and transport it along microtubules, which are the roads of the cell. However, the molecular transporters are a billion times smaller than trucks and can only move as far as the beginning or end of the microtubule, depending on their type. They have to fight their way through a crowd that is more like a busy pedestrian area than a motorway, and also have to compete with motors that want to move in the opposite direction, as scientists at the Max Planck Institute of Colloids and Interfaces in Potsdam have now discovered in a computer simulation.

Several motors are always involved in the tug-of-war over a cargo - for example, some of the kinesin type and some of the dynein type. The kinesin motors move to the end of the microtubule that biologists call the positive end, while the dynein motors move to the minus end. The findings of the Potsdam-based scientists show that the stronger motor team determines the direction in which the cargo is moved. It involves a tug-of-war where opposing motors break off from the microtubule. It was previously assumed that there was a system of coordination that allowed for only one team of motors; it was believed this alternated between one team and the other.

"The tug-of-war is the simplest imaginable mechanism," says Melanie Mueller, one of the scientists involved in the project. "But it is possible, if you consider the properties of the individual motors measured experimentally. They produce a strong non-linear reaction when they are pulled." A motor from the losing team is subject to a strong force and is quickly removed from the microtubule. The remaining motor
'/>"/>

Contact: Melanie J.I. Mueller
mmueller@mpikg.mpg.de
49-331-567-9623
Max-Planck-Gesellschaft
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Scientists successfully awaken sleeping stem cells
2. How is H pylori adhesion to gastric cells associated with MUC1 mucin VNTR size?
3. Post brain injury: New nerve cells originate from neural stem cells
4. Blood Stem Cells Originate in the Placenta
5. Einstein researchers genetically engineer immune cells into potent weapons for battling HIV
6. Fugitive cancer cells can be blocked by stopping blood cells that aid them
7. Cell recycling protects tumor cells from anti-cancer therapy
8. UCLA researchers find blood stem cells originate and are nurtured in the placenta
9. Protein in Human Embryonic Stem Cells Controls Malignant Tumor Cells
10. Greatest Satisfaction Preserving Granddaughters Cord Blood Stem Cells
11. Neural progenitor cells as reservoirs for HIV in the brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tug of war in the cells
(Date:4/17/2014)... have identified new pain relief targets that could ... BBSRC-funded researchers at King,s College London made the ... in the periphery of the body. , Dr ... identifying mechanisms underlying pain generation and our findings ... side effects." , One potential side effect of ...
(Date:4/17/2014)... 17, 2014) Two recent papers by a ... colleagues may help scientists develop treatments or vaccines ... Japanese encephalitis and other disease-causing flaviviruses. , Jeffrey ... molecular genetics at the School of Medicine and ... Medical Institute, and colleagues recently published articles in ...
(Date:4/17/2014)... (April 17, 2014) Doctors who treat patients ... lymphangioleiomyomatosis (LAM) can face an agonizing treatment decision. ... the disease and help relieve shortness of breath. ... and sirolimus can cause potentially fatal complications following ... Dr. Daniel Dilling, medical director of Loyola University ...
(Date:4/17/2014)... Medicine (BUSM) have discovered that the anti-seizure drug ... The findings, reported in the American Journal ... to more effective treatments for alcoholism. , Excessive ... causes of illness and death in the U.S. ... the productivity of workers and necessitating huge health ...
(Date:4/17/2014)... YORK (17 April 2014) Population Council scientists and their ... safe, stable, and can prevent the transmission of multiple ... rectum in animals: HIV, herpes simplex virus 2 (HSV-2), ... the first data that the gel is effective against ... efficacy in the vagina against all three viruses of ...
Breaking Medicine News(10 mins):Health News:New pain relief targets discovered 2Health News:CU researchers discover target for treating dengue fever 2Health News:Patients with rare lung disease face agonizing treatment dilemma 2Health News:Patients with rare lung disease face agonizing treatment dilemma 3Health News:BUSM researchers find anti-seizure drug may reduce alcohol consumption 2Health News:Animal study provides first evidence that gel can prevent multiple virus transmission in vagina/rectum 2
... risk of type 2 diabetesPORT ST. LUCIE, Fla., March 24 ... Diabetes Association urges all Americans to learn about type 2 ... educate the public, the American Diabetes Association and one of ... up to provide an online video that explains the symptoms ...
... Offers New Option for Adult Patients Suffering From ... Wyeth Pharmaceuticals, a division of Wyeth (NYSE: ... Food and Drug Administration (FDA) approved TYGACIL(R) (tigecycline), ... bacterial pneumonia (CABP) caused by susceptible strains of ...
... drives Victoria,s Secret Fashion Show and Armani Exchange model ... a cureHOLLYWOOD, Fla., March 24 Brazilian supermodel Izabel ... Ambassador for the Diabetes Research Institute Foundation, the nonprofit ... at the world-renowned Diabetes Research Institute (DRI) at the ...
... Israel, Iran, Saudi Arabia, Kuwait, the United Arab Emirates ... in Indianapolis April 1 and 2 for the First ... , A unique event, this conference will bring together ... foster collaboration between physicians from Western and Middle Eastern ...
... laser surgeon in Beverly Hills, appeared on The Doctors TV Show, ... the most comprehensive center specializing in laser technology and non-invasive aesthetic ... ... Beverly Hills, CA (PRWEB) March 24, 2009 -- Dr. Simon ...
... California is making health care easier and more accessible ... Proveedor Medico , the Spanish version of its existing English ... allows all visitors - even if they,re not yet Blue ... doctors and hospitals to help them make more informed decisions ...
Cached Medicine News:Health News:American Diabetes Association Alert(R) Day Video - Do You Have Diabetes? 2Health News:American Diabetes Association Alert(R) Day Video - Do You Have Diabetes? 3Health News:American Diabetes Association Alert(R) Day Video - Do You Have Diabetes? 4Health News:FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia 2Health News:FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia 3Health News:FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia 4Health News:FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia 5Health News:FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia 6Health News:FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia 7Health News:Supermodel Izabel Goulart Partners With Diabetes Research Institute Foundation as International Ambassador 2Health News:Supermodel Izabel Goulart Partners With Diabetes Research Institute Foundation as International Ambassador 3Health News:Dr. Simon Ourian, Pioneer Laser Surgeon, Appears on The Doctors TV Show 2Health News:Dr. Simon Ourian, Pioneer Laser Surgeon, Appears on The Doctors TV Show 3Health News:Dr. Simon Ourian, Pioneer Laser Surgeon, Appears on The Doctors TV Show 4Health News:Blue Shield of California Launches Online Spanish-Language Service to Help Members Choose a Medical Provider 2Health News:Blue Shield of California Launches Online Spanish-Language Service to Help Members Choose a Medical Provider 3
(Date:1/15/2014)... GRAND RAPIDS, Mich. , Jan. 15, 2014 As ... of the flu virus, select Meijer pharmacies in ... and strep throat to eligible patients, enabling Meijer pharmacists to ... under strict protocol set by a physician participating in the ...
(Date:1/15/2014)... , Jan. 15, 2014  Novation, the leading health care ... new IT value-added reseller (VAR) national contracts that expand ... and services at lower costs. These include manufacturer product ... as initiative assistance and ongoing IT consulting support. ...
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts General ... AMGN ) announced today that they ... and validate new therapeutic targets and develop novel ... disorder that affects millions worldwide. The MGH-Broad-Amgen collaboration ...
Breaking Medicine Technology:Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4
... Speakers Group (WWSG) , an innovative leader transforming the ... is proud to announce its exclusive representation of ... Human Services Secretary, EPA Administrator and three-term governor of ... in both the private and public sectors, Governor Leavitt ...
... 19 Accium BioSciences, a leading provider of bioanalytical ... today new pricing for its AMS measurement service at ... $115 per sample. The new pricing includes sample graphitization ... expert bioanalytical and quality assurance services at competitive rates. ...
Cached Medicine Technology:Governor Michael O. Leavitt, Former HHS Secretary and EPA Administrator, Selects WorldWide Speakers Group for Exclusive Representation 2Accium BioSciences Announces $99 Sample Pricing for Its Accelerator Mass Spectrometry (AMS) Measurement Service 2
... The Bayer Immuno 1 provides ... immunoassay instrument with over 50 ... endocrinology, tumor marker, therapeutic drug, ... can be performed on a ...
... The new Synchron LXi 725 clinical ... with highly accurate immunoassay testing capabilities, ... handling on a single platform. After ... automatically repeated for optimal quality assurance. ...
...
...
Medicine Products: