Navigation Links
Trial finds tenofovir gel safe for daily use and most women adhered to study regimens
Date:2/25/2008

NEW DELHI, Feb. 25, 2008 A vaginal microbicide that incorporates an antiretroviral (ARV) drug normally used to treat people with HIV is safe for sexually active HIV-negative women to use every day over an extended period, suggest results of a clinical trial of tenofovir topical gel. Moreover, most of the women who participated in the study conducted in India and the United States adhered to a regimen involving either daily or sex-dependent use of the gel, report researchers from the U.S. National Institutes of Health-funded Microbicide Trials Network (MTN) at Microbicides 2008, an international meeting taking place Feb. 24-26 at the Hotel Ashok in New Delhi.

The findings, presented today for the first time, are a significant boost to HIV prevention efforts focused on the potential of "next-generation" microbicides to curb infection rates in women. Globally, nearly half of those living with HIV/AIDS are women, and between 70 and 90 percent of all HIV infections in women are due to heterosexual intercourse. In India and many other parts of the world, even married women and women with steady partners are at risk.

In this Phase II study, called HPTN 059, researchers wanted to understand if tenofovir was safe to use every day for six months compared to its use prior to each act of sex, and if women were able to adhere, or follow, each regimen. Researchers found both approaches equally safe and womens adherence to product use similar. Interestingly, most participants also said they would be willing to apply gel, including daily, if one were found effective to prevent against getting HIV from their sexual partners.

Microbicides are products designed to prevent the sexual transmission of HIV when applied topically on the inside of the vagina or rectum. Tenofovir gel is among a newer class of candidate microbicides that differ from early types because they have specific action against HIV. In addition, because tenofovir gel and similar produ
'/>"/>

Contact: Lisa Rossi
rossil@upmc.edu
412-916-3315
Microbicide Trials Network
Source:Eurekalert

Page: 1 2 3 4 5 6

Related medicine news :

1. Hyperion Therapeutics Announces Enrollment of First Patient in Phase 2 Clinical Trial in Patients With Hepatic Encephalopathy
2. DATATRAK Closes Second Multi-Year Enterprise Agreement with European Clinical Trial Sponsor
3. Scientists move towards stem cell therapy trials to mend shattered bones
4. Positive results from phase 1 clinical trials of cuprindro
5. ESFs EMRC strengthens training course on clinical trials management
6. NIH report on intracranial stent points out need for upcoming large-scale clinical trial
7. Duragesic Trials Continue - Plaintiffs Optimistic After Latest Recall
8. Cancer Drug Works Against MS in Early Trial
9. Upcoming meeting will explore new technologies for glaucoma clinical drug trials
10. St. Davids Medical Center First in Texas to Implement Visually Guided Catheter Ablation for Atrial Fibrillation
11. Orqis(R) Medicals MOMENTUM Trial Abstract Accepted for Late Breaking Clinical Trial Presentation at the American College of Cardiology Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... FRIDAY, Sept. 19, 2014 (HealthDay News) -- U.S. military ... risk of skin cancer, according to a new study. ... serving abroad, researchers revealed. In some cases, military personnel ... in the color, shape or size of their moles ... can be risk factors for skin cancer, the study ...
(Date:9/19/2014)... U.S. Food and Drug Administration approved a new type 2 ... class of once-a-week injectable drugs that help manage blood sugar ... is a new treatment option, which can be used alone ... levels in the overall management of type 2 diabetes," Dr. ... Evaluation II, said in an agency news release. ...
(Date:9/19/2014)... a leading anti-ageing clinic has called its HGH Therapy ... has grown tremendously across USA in the last decade with ... It has far reaching benefits for ageing men and women ... and active lifestyle even beyond their middle age. , ... MetroMD said, “HGH or Human Growth hormones are the building ...
(Date:9/19/2014)... published today in the online journal PLoS Outbreaks ... West Africa by the end of the month if ... State University and Harvard University researchers also discovered through ... significantly increased in August in Liberia and Guinea, around ... place, indicating that the mass quarantine efforts may have ...
(Date:9/19/2014)... September 19, 2014 Famous Vancouver company, ... that it has now become a one-stop-solution for heating, ... businesses in Vancouver. The company has achieved this status ... to its customers. While there are many companies that ... have a single vendor who can offer all of ...
Breaking Medicine News(10 mins):Health News:Some U.S. Troops May Face Greater Skin Cancer Risk 2Health News:FDA Approves Another Weekly Injectable Drug for Type 2 Diabetes 2Health News:MetroMD Announces Better HGH Therapy - the ‘God Particle’ of Human Health 2Health News:Research predicts possible 6,800 new Ebola cases this month 2Health News:Pro Ace Now Provides Heating, Air Conditioning, Plumbing & Electrical Services under One Roof 2
... to try it than highest scorers, study found , ... young males has been linked to a much higher ... their most intelligent counterparts, researchers say. , The analysis, ... doesn,t prove that low intelligence causes suicide. Instead, it ...
... Researchers at Mount Sinai School of Medicine have developed ... in reversing advanced heart failure. SERCA2a (produced as MYDICAR) ... an enzyme that enables the failing heart to pump ... through a routine minimally invasive cardiac catheterization was safe ...
... Geneva 3 June 2010. Following a workshop hosted by ... and physicists today published a strategy for harnessing physics ... long history of application in medicine. Today,s news recognises ... collaboration. The workshop, which was the first of ...
... , ... round of 30 Days of Intentions to mark the mid-point of 2010. , ... Los Angeles, CA (PRWEB) June 3, 2010 -- This ... 2010. The 30 Days of Intentions is a challenge to the internet community to commit to ...
... Theurer Cancer Center at Hackensack University Medical Center announced ... abstracts on treatment and diagnostic progress in many different ... Society of Clinical Oncology (ASCO) in Chicago, IL from ... Cancer Center, we,re dedicated to providing extraordinary cancer care ...
... ... supplements, drugs, and medical conditions that can affect the color and odor of urine. , ... Boston, MA (Vocus) June 4, 2010 -- If ... beets turns urine pink or red—which can be alarming because it looks like blood in the ...
Cached Medicine News:Health News:Low IQ Among Males Raises Suicide Risk 2Health News:New gene therapy proves effective in treating severe heart failure 2Health News:Physicists and medics set out strategy on physics for health 2Health News:Intent.com Launches 30 Days of Intentions and Announces Winners of 2010 Intent Web Awards 2Health News:Leading physicians and researchers at the John Theurer Cancer Center present research at ASCO 2Health News:Leading physicians and researchers at the John Theurer Cancer Center present research at ASCO 3Health News:Color, Odor Changes in Urine Usually -- But Not Always -- Harmless, Reports Harvard Women's Health Watch 2
(Date:9/19/2014)... Sept. 19, 2014 /PRNewswire-iReach/ -- "United ... 2020″, provides key market data on ... market. The report provides value, in ... (in units) within market categories – ... Esophagoscopes & Gastroscopes, Duodenoscopes, Laparoscopes, Hysteroscopes, ...
(Date:9/19/2014)... N.C. , Sept. 19, 2014  For ... cloud-based drug design and development, partnering is an ... mission is to design new drugs and identify ... 2 partners to further their development. The company ... investments. To support this business model, Cloud Pharmaceuticals ...
(Date:9/19/2014)... FLINT, Mich. , Sept. 19, 2014  Diplomat, ... appointment of David Dreyer to the Board ... an independent director and will also serve as chair ... has almost 30 years of accounting, financial, compliance and ... 2010, Mr. Dreyer has served as chief financial officer, ...
Breaking Medicine Technology:United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 2United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 3United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 4United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 5Cloud Pharmaceuticals Announces Partnering Sessions and Presentation Schedule 2David Dreyer Appointed to Diplomat Board of Directors 2
Inquire...
... are accurate to 1 mm. In vivo results ... patients encapsulation scar tissue. Encapsulation scar tissue can ... therefore actual projection may vary from patient to ... surgeon with a scalpel or surgical scissors. All ...
... IQmarkTM Diagnostic Workstation Software offers a ... that digitally stores many different diagnostic ... Microsofts open-architecture products in mind, our ... integration (using ActiveX controls), networking, central ...
... engineered to set a new standard for ... enter the patient demographics, select auto report ... based system uses the latest in software ... of the IQmark Holter algorithm. Simple, intuitive ...
Medicine Products: