Navigation Links
Treatment with NAC is associated with better outcomes for children with liver failure
Date:1/3/2008

A new retrospective study on the effects of N-acetylcysteine (NAC) on children with acute liver failure not caused by acetaminophen poisoning has found that the treatment was associated with a shorter hospital stay, higher incidence of liver recovery, and better survival after transplantation. The study is in the January issue of Liver Transplantation, a journal by John Wiley & Sons. The article is also available online via Wiley Interscience (http://www.interscience.wiley.com/journal/livertransplantation).

Acute liver failure in children is rare but can be fatal. Acetaminophen poisoning is a common cause, and is treated with NAC, which acts as an antidote, an anti-inflammatory agent and an antioxidant. One small, uncontrolled study suggested that NAC could also help children with non-acetaminophen induced acute liver failure, leading some medical centers to adopt the treatment. Recently, researchers led by Christine Kortsalioudaki of Kings College Hospital in London sought to retrospectively evaluate whether NAC is beneficial for those children.

They examined the medical records of 170 children who came to Kings College Hospital with non-acetaminophen induced acute liver failure between 1989 and 2004. Those treated before 1994 were not treated with NAC, while those who came after 1995 did receive NAC. All the children also received standard care to maintain normal tissue oxygenation and prevent and address complications of acute liver failure.

The children who received NAC spent fewer days in intensive care, and in the hospital overall. 43 percent survived with their native liver, compared to 22 percent of children who did not receive NAC. And death rates while awaiting transplant, after transplant, and after ten years were notably lower in children who had received NAC. Adverse effects were mentioned in just 11 percent of cases and NAC was discontinued i
'/>"/>

Contact: Amy Molnar
amolnar@wiley.com
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Thyroid treatment no quick fix for weight loss in children
2. Shorter HCV treatment shows notable success
3. Journal Sleep: A short-term dose of zolpidem is an effective treatment for insomnia
4. Research suggests new treatment suitable for all patients
5. Jefferson scientists find protein potential drug target for treatment-resistant prostate cancer
6. Photo: KFC Colonel Original and Look-a-Like Share Eye Treatment Success Story
7. Cost of glaucoma medications may impact treatment
8. Research Offers Promise for Cirrhosis Treatment
9. In largest U.S. Hep C trial, researchers determine weight-based dosing is key to optimal treatment
10. Treatment Advocacy Centers Top 10 Mental Illness Stories You Didnt Read in 2007
11. Pharmacyclics Receives Non-Approvable Letter from the FDA for Xcytrin for the Treatment of Lung Cancer Brain Metastases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2015)... 2015 A live auction will be held ... surgery centers and other medical facilities around the United States. ... lab, radiology, surgery, anesthesia, exam and much more. , ... Thursday, May 28 starting at 9:00am CDT each day. The ... 25th Avenue, Melrose Park, IL 60160. Anyone can participate ...
(Date:5/23/2015)... CA (PRWEB) May 23, 2015 Add High-Quality ... from Pixel Film Studios. , It's as simple as dragging ... utilizing the included tool for full effect. , Including ... on high-dynamic range 5k sensors making this the ultimate bundle ... prismatic flares included in this package are movie files designed ...
(Date:5/22/2015)... (PRWEB) May 22, 2015 The ... communication and capacity are intersecting to create new ... society, the opening speaker at WesternU's 34th annual ... Lieut. Gov. Gavin Newsom, a former San Francisco ... keynote speaker at the graduation ceremony for WesternU's ...
(Date:5/22/2015)... CA (PRWEB) May 22, 2015 The ... two exciting events in June. They will hold a ... Doctorate and a two-day class on Classical Chinese Medicine. ... June 3, Dr. Steve Given, the Dean of Clinical ... discuss the new First Professional Doctorate program. ACTCM is ...
(Date:5/22/2015)... East Liverpool, OH (PRWEB) May 22, 2015 ... today announced that Kyle Johnson, the health system’s Chief ... pursue other interests. Johnson has served as the company ... announced Wesley West will be joining the health system ... operations on an interim basis, while the Board of ...
Breaking Medicine News(10 mins):Health News:Over 5,200 Lots of Medical Equipment Will Be Sold by Live Auction 2Health News:Developers at Pixel Film Studios Release ProFlare 5K Prism for Final Cut Pro X. 2Health News:Newsom to WesternU Grads: The Future is Inside You 2Health News:Newsom to WesternU Grads: The Future is Inside You 3Health News:ACTCM Announces Upcoming June Events 2Health News:River Valley Health Partners Announces CFO Transition, Appointment of Interim CFO 2
... of deprivation from being in poverty and poor health. ... heart disease is potentially denying// life saving preventive treatment ... ahead of print in the journal Heart. ,A ... allocated "primary preventive" treatment, is currently calculated using the ...
... worried over the increasing malfunction of heart devices, which ... 1990 and 2002. ,The Food and Drug Administration ... physicians and heart-device manufacturers recently, which found that 4,225 ... of defibrillators failed in the previous 10 years, reports ...
... may face difficulty in keeping dental care appointments as ... memories of the abuse experience and such victims may ... of a study reported in the latest issue of ... ,The study, conducted by a team of Canadian researchers, ...
... has shown that there are few clinical comparisons available ... seeking the best individual drug for their children with ... to help make that choice. ,There are few ... relatively large variety of drugs prescribed for ADHD and ...
... is certainly one of the risk factors associated with ... Time and again, many studies have established significant relationship ... World Heart Day fast approaching may be it is ... of World Heart Day (September 25th) is “Healthy Weight, ...
... possible using anti-nicotine vaccine. ,Are you a chain smoker ... vaccine could help., ,Swiss scientists have developed a ... the smoker // with no kick, reports news portal ... by Swiss pharmaceutical firm Cytos, works by building antibodies ...
Cached Medicine News:Health News:Deprivation Can Cause Undetected Heart Problems 2Health News:Scientists Concerned Over Increasing Malfunction Of Heart Devices 2Health News:Clinical Comparisons Between ADHD Drugs Are Less 2
(Date:5/22/2015)...  BioLife Solutions, Inc. (NASDAQ: BLFS ), a leading ... storage and cryopreservation freeze media and ... or the "Company"), announced that the Company is scheduled to ... The Company is scheduled to present at the Conference at ... Grand Hyatt Hotel in New York City ...
(Date:5/22/2015)... , May 22, 2015 The ... the $13 billion global cardiac rhythm management device ... Kalorama found that Medtronic, St. Jude Medical, Boston ... 80% of this market segment. The healthcare market ... Markets , uses 2015 as a base year, ...
(Date:5/22/2015)... , May 22, 2015  The U.S. Food ... (filgrastim-sndz) -- the first biosimilar product approved in ... points toward growth in the contract manufacturing organization ... CMO industry is geared to the production of ... major biopharmaceutical products. The healthcare market research publisher,s ...
Breaking Medicine Technology:BioLife Solutions To Present At The 2015 Marcum MicroCap Conference In New York City 2Kalorama: Top Companies Dominate Cardiac Defibrillator Market 2Kalorama: Top Companies Dominate Cardiac Defibrillator Market 3Kalorama: Top Companies Dominate Cardiac Defibrillator Market 4Kalorama: First FDA-Approved Biosimilar Brings Hope for CMO Growth 2Kalorama: First FDA-Approved Biosimilar Brings Hope for CMO Growth 3Kalorama: First FDA-Approved Biosimilar Brings Hope for CMO Growth 4
... THE WOODLANDS, Texas, Sept. 30, 2011 David, a ... grandfather, felt too young to be diagnosed with prostate ... symptoms." David, under the advisement of his oncologist, decided ... first in a new therapeutic class known as autologous ...
... 30, 2011 The CyberKnife Coalition announced ... CyberKnife Robotic Radiosurgery System® have now been enrolled in ... prostate cancer patients treated with stereotactic body ... (RPCR), tracks clinical and functional outcomes of men with ...
Cached Medicine Technology:The US Oncology Network Affiliated Physicians at Forefront of Cutting-Edge Prostate Cancer Treatment 2The US Oncology Network Affiliated Physicians at Forefront of Cutting-Edge Prostate Cancer Treatment 3The US Oncology Network Affiliated Physicians at Forefront of Cutting-Edge Prostate Cancer Treatment 4First Prostate Cancer Registry for Robotic Radiosurgery Patients Enrolls More than 500 Men 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: