Navigation Links
Treatment targeting PI3K may delay resistance to anti-HER2 therapy in breast cancer patients
Date:1/23/2013

ivin," Arteaga said. "This implied that if we could get levels of survivin to decrease, these cells would become sensitive to treatment."

They also measured pretreatment levels of survivin in HER2-positive breast cancer tumors and found that higher pretreatment levels of the protein correlated with a poor response to therapy.

"This suggests that we could measure levels of survivin in tumors, and if they are high or do not decrease with treatment, we could predict that the tumor is resistant to anti-HER2 therapy and try to find alternative treatments," Arteaga said.

Arteaga and colleagues plan to continue testing PI3K inhibitors, which are already in early clinical development, in combination with other HER2 drugs in breast cancer. They also plan to measure survivin levels in HER2-overexpressing breast cancer tumors to determine if levels can predict tumors that will benefit from combination treatment.


'/>"/>
Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
2. Clinical insight improves treatment with new lung cancer drug
3. Rapid Asthma Treatment in ER May Prevent Admission
4. Novel compound demonstrates anti-leukemic effect in zebrafish, shows promise for human treatment
5. Breast cancer patients suffer treatment-related side effects long after completing care
6. Mayo Clinic offers newly approved treatment for acid reflux disease
7. Mobile Stroke Units Might Trim Time to Treatment
8. Breast Cancer Treatment Side Effects May Last for Years
9. Mouse Study Hints at New Path for Diabetes Treatment
10. Symptomatic behaviour in childhood strongly predicts psychiatric treatment as a young adult
11. Exercise improves quality of life during breast cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... AZ (PRWEB) January 23, 2015 Hastings and ... injury matters, reports a record number of legal representation client ... speaking, there has been a steady rise in the number ... work and at home throughout the Valley. With that said, ... accident be reviewed by an experienced law firm. Hastings and ...
(Date:1/22/2015)... Hollywood, California (PRWEB) January 22, 2015 The City ... 2015 at 10 a.m., to commemorate the 42nd anniversary of the ... United States. , “It’s been 42 years since the Roe vs. ... choose is still as present as ever,” said City of West ...
(Date:1/22/2015)... The Incredible Bulk is a revolutionary method put together by ... up to 30lbs in less than 12 weeks without traditional ... prompting an investigative review. , “Our Incredible Bulk review ... that allows the body to pack on a massive amount ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Juvent Sports ... at the 2015 PGA Merchandise Show to bestow a ... incredible female amateur golfer, Arlene McKitrick. The award commemorated ... amateur golf tournament win. She won her first amateur ...
(Date:1/22/2015)... 22, 2015 Carinsurancesavings.biz has released a new ... and dismemberment insurance . , Purchasing an accidental death ... very advantageous. This type of rider provides benefits if the ... be considered a lesser form of life insurance. , ...
Breaking Medicine News(10 mins):Health News:Hastings and Hastings Reports a Record Number of Client Review Requests for Slip and Fall Accidents in 2014 2Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2
... hypothesis, that early exposures boost immune response , WEDNESDAY, Sept. ... goes, exposes kids to more germs and illnesses at an ... on. , Scientists call it the ,hygiene hypothesis," but ... early infections have no effect on asthma and allergy rates ...
... , , FORT WORTH, Texas, Sept. 9 ... up their sneakers to walk or run in the American Cancer Society,s ... against cancer. Thanks to their efforts, more than $1 million has been ... For Life is an overnight event in which teams across the country ...
... , , , ... that 21 new communities are joining Pioneering Healthier Communities (PHC), its ... that help sustain healthy behaviors through environmental and policy change. ... Disease Control and Prevention (CDC). , , ...
... about the cancer causing effects of the second most prescribed ... to rest, following the largest ever study into their use. ... treatment for chronic acid reflux, or ,heartburn, a painful burning ... by almost a third of people in developed countries. ...
... that exposure to lead in the environment is associated ... those studies have looked at lead concentrations in blood, ... exposure over time. In a new study, researchers at ... University of Michigan School of Public Health found that ...
... , , WASHINGTON, Sept. 9 ... Medicine (HJF), in partnership with The Tug McGraw Foundation (TMF) and ... present " Country United: Advancing Medicine from the Frontlines to the ... Alliance. , , Country United is ...
Cached Medicine News:Health News:Day Care May Not Shield Kids From Asthma, Allergies 2Health News:Day Care May Not Shield Kids From Asthma, Allergies 3Health News:American Airlines Employees Raise $1 Million for American Cancer Society 2Health News:American Airlines Employees Raise $1 Million for American Cancer Society 3Health News:YMCA Expands Pioneering Healthier Communities Initiative to Lead Healthy Change in Communities Nationwide 2Health News:YMCA Expands Pioneering Healthier Communities Initiative to Lead Healthy Change in Communities Nationwide 3Health News:YMCA Expands Pioneering Healthier Communities Initiative to Lead Healthy Change in Communities Nationwide 4Health News:YMCA Expands Pioneering Healthier Communities Initiative to Lead Healthy Change in Communities Nationwide 5Health News:Major clinical study rejects cancer safety fears of most common heartburn treatment 2Health News:Lead in bone associated with increased risk of death from cardiovascular disease in men 2Health News:Tim McGraw and Faith Hill Lead Country United Effort to Benefit Military Medicine 2Health News:Tim McGraw and Faith Hill Lead Country United Effort to Benefit Military Medicine 3
(Date:1/23/2015)... 2015  Today the U.S. Food and Drug Administration (FDA) ... of serogroup B meningococcal disease in individuals ... which received FDA approval in October, represent a significant ... "I have heard over and over from ...
(Date:1/23/2015)... , Jan. 23, 2015 A lot of discussion ... methods for treating  certain illnesses, injuries, or conditions. As medical ... previous treatment methods with ones that they consider to be ... there is not one textbook method of treatment that stands ...
(Date:1/23/2015)... to Fight Chronic Disease (PFCD) released a public opinion poll of ... study analyzing the impact of increased cost sharing on patient adherence ... educate policy makers and the public on the costs of chronic ... the Iowa healthcare exchange could be improved ...
Breaking Medicine Technology:The National Meningitis Association (NMA) Applauds FDA Approval of Second Vaccine To Protect Against Serogroup B Meningococcal Disease 2No One-Size-Fits-All Remedy for Hernia Correction 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3
... First 23 Patients, FRAMINGHAM, Mass., SYDNEY, ... HTW), a developer of miniaturized implantable,heart pumps ... initial,results from an international clinical trial of ... were presented by Dr. Georg,Wieselthaler, cardiothoracic surgeon ...
... known that many,children get facial rashes, while teenagers tend to ... supposed to clear up., However, studies show there are ... skin conditions., Derek Lepage [spokesperson with FaceDoctor] says:, ... a,parasite, but as a bacterial infection.", "If a person ...
Cached Medicine Technology:Presentation of HeartWare Clinical Results 2Clinically Proven Treatment Offers Help to Rosacea Sufferers 2
... for Candida albicans in only five ... two enzyme color reactions to produce ... read. AlbiQuicktm is performed on a ... Incubation time is only five minutes ...
... Osiris is a ... management software and an ... the inhibition zone size ... Osiris offers built-in expertise ...
The Oxoid Biochemical Identification System (O.B.I.S.) albicans is a simple, non-hazardous colorimetric test for the differentiation of Candida albicans from other yeast species....
Next-generation real-time polymerase chain reaction (PCR) testing for clinical laboratories. , ,The COBAS TaqMan 48 Analyzer allows automated real-time amplification and detection of DNA or RNA f...
Medicine Products: