Navigation Links
Treatment of silent acid reflux does not improve asthma in children, NIH study finds
Date:1/24/2012

Adding the acid reflux drug lansoprazole to a standard inhaled steroid treatment for asthma does not improve asthma control in children who have no symptom of acid reflux, according to a new study funded in part by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health. Lansoprazole therapy slightly increased the risk of sore throats and other respiratory problems in children, however.

Results of this study, which was also sponsored by the American Lung Association (ALA), will appear Jan. 25 in the Journal of the American Medical Association.

"This important finding could help prevent giving unnecessary medication to children," said Susan B. Shurin, M.D., acting director of the NHLBI and a board-certified pediatrician. "Doctors have suspected that acid reflux that does not cause symptoms interferes with asthma control and should be treated. This study shows that acid reflux medication should not be given to children for possible silent reflux in hopes of improving asthma control."

Shurin added that a previous NHLBI/ALA-funded trial from 2009 found that acid reflux drugs do not improve asthma control in adults who do not have symptoms of acid reflux.

Acid reflux occurs when stomach acid escapes to the adjoining esophagus. This condition occurs commonly in children and adults with asthma, although sometimes it can be silent and show none of the obvious symptoms such as heartburn, vomiting, and difficulty swallowing. Lansoprazole suppresses the production of stomach acid.

To test whether reflux treatment improves asthma control in children, researchers at 18 ALA Asthma Clinical Research Centers across the United States studied 306 children and teenagers of various ethnicities aged 6-17 years. All study participants had inadequately controlled asthma despite taking inhaled corticosteroids. Approximately 40 percent of tested participants were identified as having acid re
'/>"/>

Contact: NHLBI Communications
NHLBI_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung and Blood Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Abnormal chromosome indicator of treatment and outcome in patients with rare brain tumor
2. Study tests new treatments for the winter blues
3. 2012 Gastroinstestinal Cancers Symposium reveals new advances aimed at improving treatment, prognosis and detection of GI cancers
4. Newborn screening program aims to help transform treatments for genetic diseases detected at birth
5. UH Case Medical Center publishes study on novel treatment for skin lymphoma
6. Combining 2 anti-HER2 drugs may provide better preoperative breast cancer treatment
7. Novel Stem Cell Treatment May Hold Promise for Type 1 Diabetes
8. Gene identified as a new target for treatment of aggressive childhood eye tumor
9. Treatment with light benefits Alzheimers patients, Wayne State University finds
10. Parkinsons treatment shows positive results in clinical testing
11. Short, sharp shock treatment for E. coli
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2014)... 2014 Recently, UWDress.com, an innovative company ... special occasion outfits, has launched a special offer for ... outfits are popular among worldwide clients. Now, all the ... prom dresses on its website. , Additionally, the ... around the world. Great custom made items can be ...
(Date:9/20/2014)... 2014 Final Cut Pro X Plugin ... of the Information theme for FCPX filmmakers. , “Fun, cool, ... the Information theme,” says Christina Austin, CEO of Pixel Film ... professional.” , Information features easy to use controls that give ... environment. Change the background color, color of each circle outline, ...
(Date:9/20/2014)... 2014 The children of Branches now ... active play they need. An empty lot at the ... Campus was transformed into a kid-designed playspace in less ... from Branches (@BranchesFL), ESPN (@TeamESPN), Disney (@CitizenDisney), area residents ... a playground is more than a playground. It’s a ...
(Date:9/19/2014)... Unbound , an international humanitarian organization based ... the Philippines being affected by both a tropical storm and ... to the nearest public schools while others moved to higher ... winds to portions of the northern Philippines. , The ... with more than 10 feet of water. , “It ...
(Date:9/19/2014)... Hastings and Hastings, a discount accident lawyer ... announces a record number of visitors to its new Phoenix ... serious injury cases as well as auto accident cases and ... accident cases and others. Having served the state of Arizona ... test of time when it comes to dedicated and focused ...
Breaking Medicine News(10 mins):Health News:Discounted 2014 Prom Dresses Provided By Innovative Company UWDress.com 2Health News:Today Pixel Film Studios Announced the Release of the Information Theme for Final Cut Pro X 2Health News:Volunteers Improve Miami Kids’ Lives and Futures with Play 2Health News:Volunteers Improve Miami Kids’ Lives and Futures with Play 3Health News:Volunteers Improve Miami Kids’ Lives and Futures with Play 4Health News:Double Threat in Philippines Displaces Thousands of Unbound Families 2Health News:Hastings And Hastings Announces a Record Number of Visitors to Its New Phoenix Personal Injury Website 2
... research in monkeys shows a diet high in soy could ... ,The results from two separate studies suggest the ... conjunction with the body's own estrogen, therefore making soy especially ... study researchers say they found that monkeys that fed on ...
... take hormone therapy that combines estrogen with progestin have double ... of blood clot,// according to a recent study. ,VT ... VT increases with age and is higher in men, blacks ... two- to three-fold increased risk of VT. ,Researchers studied ...
... women are at a higher risk of developing restless ... an urge to move the legs and is generally ... also report an increase in symptoms during rest, a ... worsening of symptoms at night. Symptoms tend to progress ...
... than half a million women in developing countries dies of ... and Newborn Health //are intensifying support to countries around the ... giving birth to her child. ,The report indicates ... attendants who can help a woman give birth safely, to ...
... consume more fruits, vegetables and proteins before becoming pregnant ... leukemia. Researchers believe that glutathione // is the nutrient ... studied more than 130 women who had a child ... diets to those of more than 130 women with ...
... by massive skin cancers on the face can be effectively ... the body. ,Most skin cancers arising on the face ... and treatment is sought before the cancers get out of ... and repair the damage using flaps of skin located next ...
Cached Medicine News:Health News:WHO acts to reduce the maternal death toll 2
(Date:9/19/2014)... -- CytRx Corporation (Nasdaq: CYTR ), a biopharmaceutical ... that David J. Haen , Vice President, Business ... Biotech Industry Conference on Friday, September 26 th at ... at the Millennium Broadway Hotel in New ... archived webcast of the presentation will be available on ...
(Date:9/19/2014)... -- PCI is pleased to announce it has acquired ... provider of Clinical Trial Services and Temperature Controlled ... in the United Kingdom ... in the UK/EU to support global investigational studies ... distribution capacity, as well as consultative services for ...
(Date:9/18/2014)... 18, 2014  Aratana Therapeutics, Inc. (NASDAQ: ... on licensing, developing and commercializing innovative biopharmaceutical products ... of the underwriters, option to purchase 675,000 additional ... company,s previously announced public offering of 4,500,000 shares ... being offered by Aratana Therapeutics.  With the exercise ...
Breaking Medicine Technology:CytRx to Present at BioCentury's 2014 NewsMakers in the Biotech Industry Conference 2CytRx to Present at BioCentury's 2014 NewsMakers in the Biotech Industry Conference 3PCI Announces Acquisition Of Biotec 2PCI Announces Acquisition Of Biotec 3PCI Announces Acquisition Of Biotec 4PCI Announces Acquisition Of Biotec 5PCI Announces Acquisition Of Biotec 6Aratana Therapeutics, Inc. Announces Full Exercise of Underwriters' Option to Purchase Additional Shares 2
This unique hemostatic seal provides a simple option for beating heart CABG anastomoses, allowing you to use your own hand-suturing technique without the release of cerebral emboli associated with th...
... is a supportive .035" guide wire compatible stent system ... lengths of 18 mm, 28 mm, 38 mm and ... in 12 and 16 mm lengths. The 4.0 ... Two "diameter specific" OMNILINK® stents were developed - one ...
... particular challenge in transseptal left heart catheterization ... be exchanged for a sheath with an ... position. Traditionally, such an exchange has required ... patient. Biosense Webster has overcome this problem ...
... Jude Medical's line of guiding introducers ... RAMP, and 2 piece steerable, all ... catheters when the varying curves and ... physician technique. St. Jude Medical guiding ...
Medicine Products: