Navigation Links
Treatment Eases Involuntary Laughing, Crying Tied to Alzheimer's, MS
Date:4/14/2010

Calming the condition can greatly improve patients' quality of life, experts note

WEDNESDAY, April 14 (HealthDay News) -- Involuntary crying or laughing can be a common symptom in patients with certain neurological disorders, such as Alzheimer's, multiple sclerosis or amyotrophic lateral sclerosis (ALS).

However, a combination of drugs could be the first effective long-term treatment for the problem, researchers say.

The new treatment for curbing these unwanted crying/laughing episodes -- known to doctors as "pseudobulbar affect" or PBA -- uses two drugs, dextromethorphan and low-dose quinidine.

Early indications are that the two drugs do reduce the incidence and severity of PBA episodes and improve quality of life.

"There's no FDA-approved therapy for pseudobulbar affect," noted study lead author Dr. Erik P. Pioro, director of the section for ALS and related disorders at the Cleveland Clinic in Ohio, and a member of the American Academy of Neurology (AAN). "The off-label medications that are being used have their own set of side effects and problems. So from a medical and patient care point of view, it would be very worthwhile to have an approved medication that is both safe and effective," he said.

Pioro presented the findings at a press conference held earlier this week at the AAN's annual meeting in Toronto.

The study authors note that PBA typically manifests in patients with an underlying neurological illness, including those with multiple sclerosis (MS), ALS (also known as Lou Gehrig's disease) or Alzheimer's, as well as patients suffering from other dementias and/or brain infections and injuries.

Pioro said that conservative estimates put the number of Americans with PBA at close to 2 million, although he said the figure might actually be as high as 6 million to 7 million.

Dextromethorphan is a common medication and a principle ingredient of standard cough s
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Money Worries Delay Heart Attack Treatment
2. Sinus Dynamics Reaches Milestone with Treatment of Nasal Allergy, Sinus Infection, Acute and Chronic Sinusitis Treating 25,000th Patient
3. Southampton scientists begin Phase II patient trial for new asthma treatment
4. New study of autism reveals a DNA tag (methylation) amenable to treatment
5. Increase in Autism Rate and Treatments Focus of Autism Awareness Month
6. New pyrimidine compounds may lead to improved treatments for childhood brain cancer
7. Qutenza Now Available for Treatment of Post-Shingles Pain
8. Drug Rehab Treatment Center Explains Rehabilitation Program Using YouTube
9. Childrens Hospital Bostons Pain Treatment Service is named Clinical Center of Excellence
10. Denver Plastic Surgeon Deploys Sophisticated Lasers in Modern Beauty, Anti-aging Treatments
11. Treatment resistance in some cancer cells may be reversible
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... HealthDay Reporter MONDAY, Sept. 22, 2014 ... intensive care units (NICU) set up private rooms for parents ... Researchers at one children,s hospital found that preemies gained ... their NICU switched from the traditional "open-bay" layout to private ... in the journal Pediatrics , add to evidence that ...
(Date:9/22/2014)... Alan Mozes HealthDay Reporter ... Many American parents are aware of online physician-rating sites, and ... for their children, according to a new national study. ... parents -- further suggest that negative online ratings may dissuade ... been recommended by a neighbor. Conversely, a positive online ...
(Date:9/22/2014)... whole eye transplant seems futuristic, if not impossible. ... Department of Defense, researchers at University of California, ... make implantation of an entire, functional eye a ... a holy grail for vision restoration," said Jeffrey ... co-recipient with colleagues at University of Pittsburg Medical ...
(Date:9/22/2014)... scientists have found that an anticonvulsant drug may help ... Although dozens of antibiotics target what bacteria do, their ... bacteria are created, and they found there is a ... important as there is growing concern worldwide about how ... The World Health Organization has declared that antibiotic resistance ...
(Date:9/22/2014)... PITTSBURGH, PA (PRWEB) September 22, 2014 ... caring for patients to the problem of side-sleeping. "My ... my side, so I designed a solution to this ... fall asleep comfortably than to have your arm 'fall ... sleep on his or her side more comfortably. It ...
Breaking Medicine News(10 mins):Health News:Newborn ICUs With Private Family Rooms Benefit Preemies: Study 2Health News:Newborn ICUs With Private Family Rooms Benefit Preemies: Study 3Health News:Many Parents Use Online Ratings to Pick a Pediatrician, Study Finds 2Health News:Many Parents Use Online Ratings to Pick a Pediatrician, Study Finds 3Health News:Looking ahead: Whole eye transplant under development 2
... Many baby boomers,incorrectly believe they have disability income ... Interactive(R) on behalf of America,s Health,Insurance Plans (AHIP). ... their income, but nearly half say they do ... http://www.newscom.com/cgi-bin/prnh/20040830/AHIPLOGO ), "Baby boomers recognize the ...
... JUPITER, Fla., May 22 Atlas Spine, Inc., ... fusion and non-fusion,products, announced today the national launch ... VBR is a radiolucent MIS compatible spacer,system designed ... of,various pathologies of the thoracic and lumbar spine., ...
... As Part Of Its Summer-Long Harley-Davidson ... 105th Anniversary Celebration Promotion, MILWAUKEE, May 22 ... Association (MDA) for every Miller Lite,bottle cap collected now through ... promotion. Miller Lite, the "ultimate light beer,",is the official beer ...
... 2008) The Foundation of the National Student Nurses ... New Jersey Regional Faculty Fellowships to two Rutgers College ... , The fellowship will help Ho-Shing, a Union, N.J. ... tuition, academic fees, and book expenses during the Fall ...
... Parental Reassurance, NEW YORK, May 22 ... biosensor and microprocessor technologies for,use in portable monitoring ... its latest homecare wellness product using SPO,s patented,technology ... home baby,monitor market., Each year, there are ...
... $4 MILLION INVESTMENT WILL SUPPORT AMERICA,S NEW GENERATION ... The National,Alliance for Hispanic Health (the Alliance) announced ... a new,partnership improving Hispanic student access to higher ... (STEM). The Program is,made possible through a $4 ...
Cached Medicine News:Health News:Many Baby Boomers Incorrectly Believe They Are Protected Against the Risk of Disability 2Health News:Many Baby Boomers Incorrectly Believe They Are Protected Against the Risk of Disability 3Health News:Atlas Spine Launches Stature(TM) Vertebral Body Replacement System 2Health News:Miller Lite Bottle Caps Equal Cash for MDA This Summer 2Health News:Miller Lite Bottle Caps Equal Cash for MDA This Summer 3Health News:SPO Medical Announces Entry into the Global Baby Monitor Consumer Market 2Health News:SPO Medical Announces Entry into the Global Baby Monitor Consumer Market 3Health News:Elizabeth, NJ Chosen for Alliance/Merck Ciencia (Science) Hispanic Scholars Program 2Health News:Elizabeth, NJ Chosen for Alliance/Merck Ciencia (Science) Hispanic Scholars Program 3Health News:Elizabeth, NJ Chosen for Alliance/Merck Ciencia (Science) Hispanic Scholars Program 4Health News:Elizabeth, NJ Chosen for Alliance/Merck Ciencia (Science) Hispanic Scholars Program 5
(Date:9/22/2014)... , Sept. 22, 2014  AbbVie (NYSE: ... several clinical studies evaluating potential new medicines in ... the upcoming 2014 European Society of Medical Oncology ... Madrid, Spain . Data being presented include ... safety and efficacy of veliparib (ABT-888), a poly ...
(Date:9/22/2014)... Sept. 22, 2014 Arena Pharmaceuticals, Inc. (NASDAQ: ... to present a corporate overview and update at the ... 26, 2014, at 11:30 a.m. Eastern Time (8:30 a.m. ... New York City . A ... under the investor relations section of Arena,s website at ...
(Date:9/22/2014)... -- According to the new market ... Media and Reagents), by Source, by type, by ... Testing, Research, Drug Discovery) - Analysis & Global ... studies the major market drivers, threats, opportunities, and ... tables and 64 figures spread through 225 pages ...
Breaking Medicine Technology:AbbVie to Present Clinical Study Data on Potential New Oncology Medicines at the 2014 European Society of Medical Oncology Annual Meeting 2AbbVie to Present Clinical Study Data on Potential New Oncology Medicines at the 2014 European Society of Medical Oncology Annual Meeting 3AbbVie to Present Clinical Study Data on Potential New Oncology Medicines at the 2014 European Society of Medical Oncology Annual Meeting 4Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference 2Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference 3Cell Line Development Market Worth $3.96 Billion by 2019 2Cell Line Development Market Worth $3.96 Billion by 2019 3Cell Line Development Market Worth $3.96 Billion by 2019 4
... YORK, May 22, 2012  Fox Insurance Company, a Medicare ... announces the confirmation of a judgment in the arbitration ... manager, in excess of $3.3 million, following a suit ... breach of contract.  On May 21, 2012, the U.S. ...
Denmark...
Cached Medicine Technology:Judge Upholds $3.3 Million Judgment In Favor of Fox Insurance Company Against Former Pharmacy Benefit Manager 2
... Human Insulin-like growth factor binding protein-2 ... (further IGFBPs have been proposed) which specifically ... and IGF-II. The binding affinity of IGFBP-2 ... higher than for IGF-I [1], suggesting a ...
... Insulin-like growth factor binding protein-2 (IGFBP-2) is ... have been proposed) which specifically bind and ... The binding affinity of IGFBP-2 for IGF-II ... for IGF-I [1], suggesting a role in ...
... Androstenedione, produced in the adrenal gland and ... testosterone and estrone, both of which may ... relatively weak androgenic activity, estimated at ~(less ... [1]. However, serum androstenedione levels often exceed ...
... proteins that suppress the secretion of FSH ... consists of two distinct chains, or subunits ... consists of the alpha-subunit and betaA-subunit. Inhibin ... Only the dimeric forms of the molecule, ...
Medicine Products: