Navigation Links
Treating Stomach Infection Early Protects Against Cancer

Study finds early use of antibiotics reversed damage caused by H. pylori

FRIDAY, May 2 (HealthDay News) -- Prompt treatment of a common stomach infection reverses the damage that can lead to gastric cancer, according to tests on mice done by researchers at the Massachusetts Institute of Technology (MIT).

The findings should put a stop to any questions about whether, and when, antibiotic treatment of Helicobacter pylori can reduce or eliminate the risk of developing stomach cancer.

"We concluded that H. pylori eradication prevented gastric cancer to the greatest extent when antibiotics were given at an early point of infection, but that eradication therapy given at a later point also delayed the development of severe lesions that can lead to cancer," study author James G. Fox, director of the division of comparative medicine at MIT, said in a prepared statement.

Stomach cancer is the second-leading cause of cancer death worldwide and about half the world's population is infected with H. pylori, which is recognized as a major cause of both peptic ulcers and stomach cancer. It typically takes several decades for stomach cancer to develop in people who are susceptible -- about 3 percent of people infected with H. pylori.

It's been unclear when doctors should screen and treat people with antibiotics -- other than immediate relatives of patients with stomach cancer and peptic ulcer disease -- or when to treat H. pylori infection for maximum benefit, Fox said.

He and his colleagues created mice prone to accelerated H. pylori infection and progression to stomach cancer. The researchers found that mice treated with antibiotics had less severe disease at every stage of advancing infection.

Mice treated eight weeks post-infection had the same risk of cancer as uninfected mice. However, treatment at 12 and 22 weeks post-infection didn't reverse damaging changes, such as inflammation and development of precancerous lesions, to levels seen in uninfected mice.

"Our mouse model mimics the progressive process we know occurs in the development of human gastric cancer. This [study] shows early intervention provides the maximum benefit," Fox said.

The study appears in the May 1 issue of Cancer Research.

More information

The American Cancer Society has more about stomach cancer.

-- Robert Preidt

American Association for Cancer Research, news release, May 1, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. HPV vaccine does not appear to be effective for treating pre-existing HPV infection
2. Is 4 agents decoction (Si Wu Tang) efficacious in treating primary dysmenorrhea?
3. Treating diabetes during pregnancy can break link to childhood obesity
4. Jefferson specialists studying innovative surgery for effectively treating sleep apnea
5. Treating Diabetes During Pregnancy Could Lead to Thinner Kids
6. Family-based treatment more effective than supportive psychotherapy in treating bulimia
7. Treating depression may improve recovery of heart rate variability following coronary syndromes
8. Antidepressant shows early promise in treating agitation and psychotic symptoms of dementia
9. Hospitals Improve Survival Rates While Treating Sicker Patients Thomson Healthcare Study Shows
10. Stem cells show promise for treating Huntingtons disease
11. Treating obstructive sleep apnea, preventing heart attacks and strokes
Post Your Comments:
Related Image:
Treating Stomach Infection Early Protects Against Cancer
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health and ... Applying the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD ... that can be easily incorporated into liquid products, while reducing costs to end users. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released a ... books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture of ... have tossed it off as mere rubbish, but Yisrayl Hawkins says that is because ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian ... On The Brink” is the creation of published author, William Nowers. Captain Nowers ... a WWII veteran, he spent thirty years in the Navy. Following his career ...
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Cohen Veterans Bioscience and Early Signal Foundation ... and home sensors for real-time monitoring of patients with ... nonprofit organization focused on disruptive health solutions for rare ... system to record and integrate behavioral, cognitive, physiological and ... ...
(Date:9/25/2017)... 25, 2017  EpiVax, Inc., a leader in ... immune-engineering today announced the launch of EpiVax Oncology ... personalized therapeutic cancer vaccines. EpiVax has provided $500,000 ... to enabling technologies to the new precision immunotherapy ... EpiVax Oncology as Chief Executive Officer. Gad brings ...
(Date:9/19/2017)... 2017 HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, ... three leadership team developments today:   ... ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has ...
Breaking Medicine Technology: