Navigation Links
Treating Sperm With Missing Protein Might Help Male Fertility
Date:9/21/2012

FRIDAY, Sept. 21 (HealthDay News) -- Some forms of male infertility could possibly be treated with a missing protein, an early new study suggests.

Sperm transfers this vital protein -- known as known as PLC-zeta (PLCz) -- to an egg during fertilization to trigger the processes needed for embryo development.

In lab experiments, researchers were able to prepare active human PLCz. They found that adding PLCz to sperm with defective protein allowed for fertilization.

This, they say, could significantly increase the likelihood of a successful pregnancy.

"We know that some men are infertile because their sperm fail to activate eggs. Even though their sperm fuses with the egg, nothing happens. These sperm may lack a proper functioning version of PLCz, which is essential to trigger the next stage in becoming pregnant," study co-leader Tony Lai, a professor at Cardiff University's Institute of Molecular and Experimental Medicine, said in a university news release.

"However, when an unfertilized egg is injected with human PLCz, it responds exactly as it should do at fertilization, resulting in successful embryo development to the blastocyst stage, vital to pregnancy success," Lai said.

The researchers' methods were limited to laboratory experiments and could not be duplicated in a fertility clinic in the same way, Lai acknowledged. Still, he said, the findings might lead to the development of a new treatment for men with certain forms of infertility.

"In the future, we could produce the human PLCz protein and use it to stimulate egg activation in a completely natural way," he concluded. "For those couples going through IVF treatment, it could ultimately improve their chances of having a baby and treat male infertility."

The study was published online Sept. 21 in the journal Fertility and Sterility.

More information

Visit the U.S. National Institutes of Health to learn more about male infertility.

-- Mary Elizabeth Dallas

SOURCE: Cardiff University, news release, Sept. 21, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study Suggests Treating Dyslexia Before Kids Learn to Read
2. New standards for treating traumatic shoulder injuries to improve patient care
3. Treating childhood obesity: A family affair
4. Unique physiology key to diagnosing and treating diabetes in Asian populations
5. Studies See Advances in Detecting, Treating Pancreatic Cancer
6. 1 size doesnt fit all when treating blood pressure in people with diabetes, VA/U-M study suggests
7. Nanomedicines promise fewer side effects in treating cancer
8. Mount Sinai researchers develop a multi-target approach to treating tumors
9. A non-antibiotic approach for treating urinary tract infections
10. UT Southwestern study shows treating diabetes early, intensively is best strategy
11. Researchers report success in treating autism spectrum disorder
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Treating Sperm With Missing Protein Might Help Male Fertility
(Date:12/2/2016)... ... 2016 , ... Sourced from the Isbre Springs beneath the 5,000 year old ... purity of just 6 ppm TDS (Total Dissolved Solids) in addition to its excellent ... in several ShopRite and FoodTown stores in NJ and received rave comments from consumers. ...
(Date:12/2/2016)... ... December 02, 2016 , ... Yisrayl Hawkins, at The House of Yahweh in ... fits into Bible Prophecy. Yisrayl says this generation, known as the Last Generation, started ... how the details line up exactly with Bible Prophecy – a protected way for ...
(Date:12/2/2016)... ... December 02, 2016 , ... Clarify Health Solutions, Inc., ... $6.0 million in an initial round of funding. The round was led by ... caregivers can receive far better care through the application of the best technologies ...
(Date:12/2/2016)... ... 2016 , ... Today CloudMine, a secure, cloud-based platform that ... best Sales Team of 2016 as part of the 2016 SIIA Company CODiE ... & Information Industry Association (SIIA), the principal trade association for the software and ...
(Date:12/2/2016)... ... 02, 2016 , ... ‘Tis the season for giving! Today, 20 creative teams ... Family Partnership and the Drug Enforcement Administration as part of the National Red Ribbon ... winning schools who decorated their campuses with this year’s Red Ribbon Week theme: “YOLO. ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... On Thursday, the NASDAQ Composite and the S&P ... Jones Industrial Average managed to stay in green. Losses were ... Stock-callers this morning to look at the performances of the ... Smith & Nephew PLC (NYSE: SNN ), Nxstage ... Inc. (NASDAQ: KOOL ). You can access our ...
(Date:12/2/2016)... 1, 2016 Around the corners of world, ... each habitable land present over earth. Cancer has become ... in a life time this is because of the ... now. Given the steady increase in global cancer incidence ... spiraling healthcare costs of treatment, there is increasing interest ...
(Date:11/30/2016)... , Nov 30, 2016 Research and Markets ... Pressure Monitoring Devices 2017 - MedCore" report to their offering. ... , , ... and the skull. In healthy individuals, it is circulated though the brain ... cases where the amount of CSF surrounding the brain changes significantly. ...
Breaking Medicine Technology: