Navigation Links
Transplant Drug Shrinks Tumors in Women With Rare Lung Disease
Date:1/10/2008

Sirolimus reduced growths by 50% for sufferers of LAM

THURSDAY, Jan. 10 (HealthDay News) -- Women who are struck by a rare lung disease could find their tumors shrink by 50 percent with the help of the transplant drug sirolimus, a new study suggests.

The Cincinnati researchers who made the discovery also demonstrated the drug might improve lung function in some patients over time.

Lymphangioleiomyomatosis (LAM), a disease that exclusively targets women, is characterized by progressive loss of lung function due to the invasion of abnormal muscle tissue that obstructs airways. In its early stages, LAM can be confused with emphysema because of its effects on breathing. People with LAM often need oxygen treatments and lung transplants as the disease continues its course. According to the American Lung Association, as many as 250,000 women worldwide might have the disease.

The new treatment was also effective in reducing tumors in patients suffering from tuberous sclerosis complex (TSC), a rare genetic multi-system disease.

The two diseases share a genetic mutation that affects the activation of the enzyme mTOR, which is responsible for controlling the growth and spread of cells. Sirolimus, a drug that is usually prescribed to prevent the rejection of transplanted organs, also prevents mTOR activity, according to the researchers. Sirolimus is also known as rapamycin (Rapamune).

Publishing in the Jan. 10 edition of the New England Journal of Medicine, the researchers concluded that sirolimus has the potential to help patients with either disease avoid surgery for the tumor angiomyolipomata, common to both conditions.

"Less invasive therapies are clearly needed to treat the angiomyolipomata that people with TSC and LAM develop, and a drug that maintains or shrinks tumor size may reduce the need for procedures such as surgery," study author Dr. John Bissler, a physician/scientist in t
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Rural Residents Get Fewer Organ Transplants: Study
2. Childrens Hospital physicians publish review of transplant issues in patients with biliary atresia
3. RNs Statement on Death of Nataline Sarkisyan: CIGNA Should Have Listened to her Doctors and Approved the Transplant a Week Ago
4. UCLA Program Aims to Revolutionize Kidney Transplants
5. Phylonix granted broad European patent for transplanting human cells into zebrafish
6. Transplanted Bone Marrow Cells Aid Nerve Regeneration
7. High-dose chemo and stem cell transplant shows little or no survival benefit for breast cancer
8. Partial Face Transplant Patient Doing Well
9. VELCADE(R) (Bortezomib) for Injection Based Therapy Produced Significant Complete Remission Rates Pre- and Post-Transplantation in IFM Phase III Front-Line Multiple Myeloma Trial
10. Gentler chemotherapy before stem cell transplant causes long-term remission of follicular lymphoma
11. Cell Transplants Hold Promise for Heart Attack Survivors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Transplant Drug Shrinks Tumors in Women With Rare Lung Disease
Transplant Drug Shrinks Tumors in Women With Rare Lung Disease
(Date:10/10/2008)...LE, PA The American Nurses Credentialing Center (...) as a Magnet hospital. The news came via a confer...taff who broke out with cheers and applause., GMC...itals and only 294 hospitals in the United States... hospitals are eligible for this recognition., "A...
(Date:10/10/2008)...ggests poor self-care partly to blame , ,...f Medicare beneficiaries who have diabetes, being ... according to a new study. , Publishing in th...l Medicine , researchers from the University of Wa...erage age of 75.6 years) who had diabetes and were...
(Date:10/10/2008)... Honoring excellence in the imple... Healthcare Information and Management Systems Soc...Davies Awards in the Organizational, Ambulatory an... Chicago, IL (PRWEB) October 1...on of electronic health records (EHRs), the Healt...
(Date:10/10/2008)...YORK, Oct. 10 /PRNewswire/ -- The Johns Hopkins Un...ultimedia educational program,"Optimizing Adjuvan...atment,Selection," to present recent key research ...ment., In recent years, advancements in the treat... and biologic treatment combinations that are,incr...
Breaking Medicine News(10 mins):Health News:Geisinger Medical Center earns prestigious Magnet designation 2Health News:Older Diabetics With Depression Face Higher Death Rate 2Health News:2008 HIMSS Davies Awards: Nation's Outstanding Healthcare Organizations Recognized 2Health News:2008 HIMSS Davies Awards: Nation's Outstanding Healthcare Organizations Recognized 3Health News:2008 HIMSS Davies Awards: Nation's Outstanding Healthcare Organizations Recognized 4Health News:2008 HIMSS Davies Awards: Nation's Outstanding Healthcare Organizations Recognized 5Health News:Latest Research on Breast Cancer Presented in a Virtual E-Conference CME Course 2
...een lovers was imitated by a government AIDS awar...rld's highest HIV rates. This enraged activists// ...isease are promiscuous. Pictures of a mobile phon...'s have a quickie, my husband's not around', or 'C...
...Drug Administration has warned three pharmacy comp...on Thursday.// The FDA sent warning letters to Re...S Medical instructing these companies to halt the ...thousands of doses of compounded inhalation drugs ...
...d to real or threatened violence at work run a maj...s research in the Journal of Epidemiology// and Co... direct proportion to the amount of workplace viol... shows. The findings are based on the occupation...
... transmitted by contagious cancer cells which act ...ccording to scientists following their study// of ...le venereal tumor, or CTVT, is a cancer that sprea...l contact and also through licking, biting or snif...
Other Medicine News:Health News:AIDS Campaign Enrages HIV Infected Swazis 2Health News:Violence at Work Significantly Boosts Clinical Depression Risk 2Health News:Venereal Cancer in Dogs Transmitted by Contagious Cancer Cells 2
(Date:10/9/2008)...ce Institute, Navigenics, Affymetrix and,Microsoft...Oct. 9 /- A consortium of health care...es in a first-of-its-kind,research study to assess...,on people who choose to receive such screenings t...tain diseases., Sponsored by Scripps Translationa...
(Date:10/8/2008)...rm Treatments for Spinal Cord, Other Nerve,Injurie... -- A protein that enables,nerve cells to communic...g,the developing nervous system. Research into how...ong nerve cells may provide a basis for eventual,t...r nervous system,including spinal cord injury., ...
(Date:10/8/2008)...luate TAXUS(R) Element(TM) Platinum Chromium ...Oct. 8 /- Boston Scientific... has completed enrollment in,the PERSEUS trial, de...TAXUS(R) Element(TM) paclitaxel-eluting coronary s...arly 1,500 patients at 100 U.S. and,international ...
(Date:10/7/2008)...re/ -- Prometheus Laboratories Inc., a,specialty p...om its,development of PROMETHEUS(R) IBS Diagnostic...l syndrome (IBS). The findings suggest measurable,...kers in blood samples,between IBS and non-IBS pati...ined with a proprietary algorithm, led to the deve...
Breaking Medicine Technology:Landmark Research Study is Launched to Assess Impact of Personal Genetic Testing 2Landmark Research Study is Launched to Assess Impact of Personal Genetic Testing 3Landmark Research Study is Launched to Assess Impact of Personal Genetic Testing 4Landmark Research Study is Launched to Assess Impact of Personal Genetic Testing 5Protein Shown to Play a Key Role in Normal Development of Nervous System 2Protein Shown to Play a Key Role in Normal Development of Nervous System 3Boston Scientific Completes Clinical Trial Enrollment for Third-Generation Drug-Eluting Stent 2Boston Scientific Completes Clinical Trial Enrollment for Third-Generation Drug-Eluting Stent 3Boston Scientific Completes Clinical Trial Enrollment for Third-Generation Drug-Eluting Stent 4Prometheus Presents Findings From Development of PROMETHEUS(R) IBS Diagnostic, First Blood Test for IBS, at ACG Annual Scientific Meeting 2Prometheus Presents Findings From Development of PROMETHEUS(R) IBS Diagnostic, First Blood Test for IBS, at ACG Annual Scientific Meeting 3Building efficient effective locally sensitive solutions for dementia care 3467 1Building efficient effective locally sensitive solutions for dementia care 3467 2New molecules discovered that block cancer cells from modifying cell DNA 758 1New molecules discovered that block cancer cells from modifying cell DNA 758 2ReBuilder Medical Technologies Inc Announces Agreement with Internet Marketer Helio Health 3B Anticipates 12 25 Additional Profit 3466 1ReBuilder Medical Technologies Inc Announces Agreement with Internet Marketer Helio Health 3B Anticipates 12 25 Additional Profit 3466 2ReBuilder Medical Technologies Inc Announces Agreement with Internet Marketer Helio Health 3B Anticipates 12 25 Additional Profit 3466 3VitalKey Introduces the Pink Key 28R 29 3464 1VitalKey Introduces the Pink Key 28R 29 3464 2
...finity and MedImmune to Present Preclinical Data F...CAMBRIDGE, Mass. and GAITHERSBURG, Md., April 10, ... Inc. (Nasdaq:INFI) and,MedImmune, Inc. (Nasdaq:ME...tudy with an oral formulation of IPI-504 in non-sm...the upcoming Annual,Meeting of the American Associ...
...ETHESDA, Md., April 10, 2007--In a study appearing...scientists supported by the,National Institutes of...loskeletal and Skin Diseases (NIAMS) have discover...flammatory skin,condition vitiligo, as well as a p... a chronic condition in which melanocytes (the cel...
Other Medicine Technology:Infinity and MedImmune to Present Preclinical Data From Study of,Oral Formulation of IPI-504 At AACR 2Infinity and MedImmune to Present Preclinical Data From Study of,Oral Formulation of IPI-504 At AACR 3Infinity and MedImmune to Present Preclinical Data From Study of,Oral Formulation of IPI-504 At AACR 4Scientists Implicate Gene in Vitiligo and Other Autoimmune Diseases 2Scientists Implicate Gene in Vitiligo and Other Autoimmune Diseases 3
Luer Rongeur
Friedman Rongeur
Zaufal-Jansen Ronguer
Mead Rongeur #1A
Medicine Products: