Navigation Links
Transplant Drug Shrinks Tumors in Women With Rare Lung Disease
Date:1/10/2008

Sirolimus reduced growths by 50% for sufferers of LAM

THURSDAY, Jan. 10 (HealthDay News) -- Women who are struck by a rare lung disease could find their tumors shrink by 50 percent with the help of the transplant drug sirolimus, a new study suggests.

The Cincinnati researchers who made the discovery also demonstrated the drug might improve lung function in some patients over time.

Lymphangioleiomyomatosis (LAM), a disease that exclusively targets women, is characterized by progressive loss of lung function due to the invasion of abnormal muscle tissue that obstructs airways. In its early stages, LAM can be confused with emphysema because of its effects on breathing. People with LAM often need oxygen treatments and lung transplants as the disease continues its course. According to the American Lung Association, as many as 250,000 women worldwide might have the disease.

The new treatment was also effective in reducing tumors in patients suffering from tuberous sclerosis complex (TSC), a rare genetic multi-system disease.

The two diseases share a genetic mutation that affects the activation of the enzyme mTOR, which is responsible for controlling the growth and spread of cells. Sirolimus, a drug that is usually prescribed to prevent the rejection of transplanted organs, also prevents mTOR activity, according to the researchers. Sirolimus is also known as rapamycin (Rapamune).

Publishing in the Jan. 10 edition of the New England Journal of Medicine, the researchers concluded that sirolimus has the potential to help patients with either disease avoid surgery for the tumor angiomyolipomata, common to both conditions.

"Less invasive therapies are clearly needed to treat the angiomyolipomata that people with TSC and LAM develop, and a drug that maintains or shrinks tumor size may reduce the need for procedures such as surgery," study author Dr. John Bissler, a physician/scientist in t
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Rural Residents Get Fewer Organ Transplants: Study
2. Childrens Hospital physicians publish review of transplant issues in patients with biliary atresia
3. RNs Statement on Death of Nataline Sarkisyan: CIGNA Should Have Listened to her Doctors and Approved the Transplant a Week Ago
4. UCLA Program Aims to Revolutionize Kidney Transplants
5. Phylonix granted broad European patent for transplanting human cells into zebrafish
6. Transplanted Bone Marrow Cells Aid Nerve Regeneration
7. High-dose chemo and stem cell transplant shows little or no survival benefit for breast cancer
8. Partial Face Transplant Patient Doing Well
9. VELCADE(R) (Bortezomib) for Injection Based Therapy Produced Significant Complete Remission Rates Pre- and Post-Transplantation in IFM Phase III Front-Line Multiple Myeloma Trial
10. Gentler chemotherapy before stem cell transplant causes long-term remission of follicular lymphoma
11. Cell Transplants Hold Promise for Heart Attack Survivors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Transplant Drug Shrinks Tumors in Women With Rare Lung Disease
(Date:8/22/2014)... Va. (PRWEB) August 22, 2014 On ... Center for Medical and Health Sciences , hosting a ... area’s top influencers in government and public welfare. , ... College of Osteopathic Medicine (LUCOM) joined Liberty staff, ... and the launch of the new medical school. Classes ...
(Date:8/22/2014)... Las Vegas, NV (PRWEB) August 22, 2014 ... authentic content that is written by marketing experts for ... and affiliate links has caught the attention of Shane ... is involved with Internet marketing in any way knows ... or failure in the industry,” reports Michaels. “But even ...
(Date:8/22/2014)... 2014 Japantown Dental is excited to ... whitening technique. Air polishing is a technique used to ... teeth can be caused by a number of factors, ... internal stains. External stains include coffee, wine, tea, smoking ... certain medications, such as tetracycline, and direct trauma to ...
(Date:8/22/2014)... team has found that targeted automated alerts in ... in hospital patients with urinary catheters. In addition, ... the rate of improvement dramatically increased. , The ... urinary catheters in the first place and then ... that have not been removed within a recommended ...
(Date:8/22/2014)... NV (PRWEB) August 22, 2014 Natural ... Kevin Richardson to restore his own vision from legally blind ... Michaels, prompting an investigative review. , “There is a ... or contacts for everyday function, and most people just think ... to corrective eye surgery that can be pretty risky at ...
Breaking Medicine News(10 mins):Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 2Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 3Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 4Health News:My Writers: Review Exposes Online Source for Quality Marketing Content 2Health News:Japantown Dental Introduces Air Polishing 2Health News:Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections 2Health News:Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections 3Health News:Natural Clear Vision: Review Exposes Kevin Richardson’s Program for Restoring Vision Naturally 2
... Inaugural Gala, NORTH ADAMS, Mass., Nov. 14 ... today announced that it will hold,its first Roundtable meeting ... Institute, established by NPSF in May 2007, is a,think ... action for,the field of patient safety. Its goal is ...
... , Ohio -- Scientists are one step closer to ... for supporting life. , For the first time, scientists ... protein molecules to enable different functions to happen. , ... of the Proceedings of the National Academy of Sciences, ...
... your name and initials? Most people do and, as past ... other important behaviors. For example, Jack is more likely to ... is more likely to move to Philadelphia and marry Phyllis. ... it is influential enough to encourage the pursuit of name-resembling ...
... in the World Journal of Gastroenterology on November 7, ... case of gastric carcinosarcoma obtained in this part of ... Tomislav Randjelovic as surgeon and Dr. Branka Filipovic as ... his team; the anatomical and patoanatomical evaluation of macroscopic ...
... Asenapine -- a fast-,dissolving, sublingual tablet being ... and well-tolerated in patients with acute schizophrenia,according to ... of the Journal,of Clinical Psychiatry. These data were ... meeting and at the annual,congress of the European ...
... International,Isotopes Inc. (OTC Bulletin Board: INIS) is pleased ... Chief Financial Officer (CFO),effective November 13, 2007. ... 2007,as Chief Accounting Officer. Ms. McKenzie-Carter has approximately ... Previously, she served as,chief accountant for a sizeable ...
Cached Medicine News:Health News:Lucian Leape Institute Announces First Roundtable 2Health News:Lucian Leape Institute Announces First Roundtable 3Health News:Scientists get first look at how water 'lubricates' proteins 2Health News:What's in a name? Initials linked to success, study shows 2Health News:Study Shows Organon's Asenapine Demonstrates Efficacy and Tolerability in Treating Acute Schizophrenia 2Health News:Study Shows Organon's Asenapine Demonstrates Efficacy and Tolerability in Treating Acute Schizophrenia 3Health News:Study Shows Organon's Asenapine Demonstrates Efficacy and Tolerability in Treating Acute Schizophrenia 4Health News:Laurie McKenzie-Carter Named Chief Financial Officer of International Isotopes Inc. 2
(Date:8/22/2014)... Ireland , August 22, 2014 /PRNewswire/ ... and Markets ( http://www.researchandmarkets.com/research/x34qgv/global_laboratory ) has announced the ... Market 2014-2018"  report to their offering.  ... balance is an essential instrument for any ... the precise weighing of materials. It can ...
(Date:8/22/2014)...  Diplomat, the nation,s largest independent specialty pharmacy, ... in the 2014 Innovations in Specialty Pharmacy Competition, ... of the competition were announced in the August ... Diplomat was honored as a Top Innovator ... Through Diplomat University, the company has implemented a ...
(Date:8/22/2014)... , Aug. 22, 2014 Research ... "Stem Cell Research Products: Opportunities, Tools & Technologies" ... already supply stem cell research products or you wish ... essential and lucrative this market is. The authors know ... sell more effectively to scientists, to generate improved revenues ...
Breaking Medicine Technology:Global Laboratory Electronic Balance Market 2014-2018: Key Vendors are A&D Company, Mettler-Toledo, Sartorius and Thermo Fisher 2Diplomat honored as a Top Innovator by Specialty Pharmacy News 2Global Stem Cell Research Products: Opportunities, Tools & Technologies - 2014 Report 2Global Stem Cell Research Products: Opportunities, Tools & Technologies - 2014 Report 3
... 2011 Bayer HealthCare Pharmaceuticals Inc. today ... cohort safety study offer insights into the increased risk ... a well-established risk in women who use combination oral ... Specifically, the new data provides healthcare providers with information ...
... Therapeutics today announced  the initiation of a Phase ... XMT-1001 , a novel DNA topoisomerase I inhibitor based ... in second-line gastric cancer and second-/third-line non-small cell lung ... clinical centers in the US.  The Phase 1b follows ...
Cached Medicine Technology:New Interim Data About Combination Oral Contraceptives 2New Interim Data About Combination Oral Contraceptives 3New Interim Data About Combination Oral Contraceptives 4New Interim Data About Combination Oral Contraceptives 5New Interim Data About Combination Oral Contraceptives 6Mersana Therapeutics Initiates Phase 1b Extension Study of XMT-1001 in Gastric Cancer and Non-Small Cell Lung Cancer 2Mersana Therapeutics Initiates Phase 1b Extension Study of XMT-1001 in Gastric Cancer and Non-Small Cell Lung Cancer 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: