Navigation Links
Transition Therapeutics Announces Initiation of a Phase Ib Clinical Study of TT-223 in combination with a GLP-1 analogue in Patients with Type 2 Diabetes
Date:3/23/2009

TORONTO, March 23 /PRNewswire-FirstCall/ - Transition Therapeutics Inc. ("Transition" or the "Company") (NASDAQ: TTHI, TSX:TTH) announced today that the first patient has been dosed in a clinical study of gastrin analogue TT-223 in combination with a proprietary Lilly GLP-1 analogue, in patients with type 2 diabetes. The study is a randomized, double-blind, placebo-controlled study in approximately 140 patients to evaluate the safety, tolerability and efficacy of daily TT-223 treatments in combination with weekly administrations of GLP-1 analogue, for a combination treatment period of 4 weeks with a 5-month follow-up.

For information on enrollment, patients or caregivers can visit the website www.clinicaltrials.gov under study # NCT00853151

    About Gastrin-Based Therapies
    -----------------------------

Transition and Eli Lilly and Company (NYSE: LLY) have entered into a licensing and collaboration agreement granting Lilly exclusive worldwide rights to develop and commercialize gastrin based therapies, including the lead compound TT-223. Gastrin based therapies are an emerging class of potential disease-modifying therapies for patients with diabetes, and have been shown to provide sustained improvement in glycemic control in preclinical models and early clinical studies. Sustained improvement in glycemic control is a key goal for patients with diabetes in order to alleviate the symptoms of hyperglycemia and to prevent diabetic complications, and improving their overall quality of life.

    About Transition
    ----------------

Transition is a biopharmaceutical company, developing novel therapeutics for disease indications with large markets. Transition's lead products include ELND005 (AZD-103) for the treatment of Alzheimer's disease and TT-223 for the treatment of diabetes. Transition has an emerging pipeline of preclinical drug candidates acquired externally and developed internally using its proprietary drug discovery engine. Transition's shares are listed on the NASDAQ under the symbol "TTHI" and the Toronto Stock Exchange under the symbol "TTH". For additional information about the Company, please visit www.transitiontherapeutics.com.

Notice to Readers: Information contained in our press releases should be considered accurate only as of the date of the release and may be superseded by more recent information we have disclosed in later press releases, filings with the OSC, SEC or otherwise. Except for historical information, this press release may contain forward-looking statements, relating to expectations, plans or prospects for Transition, including conducting clinical trials. These statements are based upon the current expectations and beliefs of Transition's management and are subject to certain risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. These risks and uncertainties include factors beyond Transition's control and the risk factors and other cautionary statements discussed in Transition's quarterly and annual filings with the Canadian commissions.


'/>"/>
SOURCE Transition Therapeutics Inc.
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Mylan Announces Transition of Chief Financial Officer
2. Transition Therapeutics Announces Second Quarter Fiscal 2009 Financial Results
3. Transition Therapeutics to Hold Conference Call on Second Quarter Fiscal 2009 Financial Results on Wednesday, February 11th, at 4:30 P.M. EST
4. CDS Completes Large-Scale Transition of Medicare Data Processing
5. Transition Therapeutics Announces Completion of Patient Enrolment of Phase 2 Study of TT-223 in Type 2 Diabetes Patients
6. Is rapid transition through menopause linked to earlier onset of heart disease?
7. MEDai Presents on Transitioning Predictive Modeling Integration From Care Management to Actuarial Applications
8. Mental Health Leaders Meet with Transition Team
9. Carl Zeiss Vision and Transitions Optical Inc. Promote Pioneering Eyewear to Consumers
10. AUDIO from Medialink and Transitions Optical: New Years Resolutions for Healthier Eyes
11. Carl Zeiss Vision and Transitions Optical Inc. Promote Pioneering Eyewear to Consumers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... (PRWEB) , ... January 17, 2017 , ... Recently, patients ... in Southwest Michigan, joined other volunteers and organizations in support of the annual Binder ... children and families dressed up in colorful costumes of all designs coming out to ...
(Date:1/16/2017)... Elk Grove Village, IL (PRWEB) , ... January ... ... protection and personal audio products, will demonstrate their groundbreaking GunSport•PRO® and EB15•LE® electronic ... Expo and Convention Center in Las Vegas, Booth #2809. The SHOT Show is ...
(Date:1/16/2017)... ... January 16, 2017 , ... Houston ... Center, is currently offering complimentary consultations and financing for orthodontics for a limited ... bite irregularities and learn about their orthodontic options. Walk-in, late-evening, Saturday, and same-day ...
(Date:1/16/2017)... ... January 16, 2017 , ... Specialty Technical Publishers (STP) ... Audit Protocol Consortium (IAPC) EHS audit protocol for Singapore . Leading companies ... their EHS regulatory obligations and rapidly collect, share, archive, and export audit findings ...
(Date:1/16/2017)... Grants Pass, OR (PRWEB) , ... January 16, ... ... Kent Heckenlively, author, editor, attorney, science teacher, http://www.ageofautism.com/legal , Sharon Kleyne, ... and attorney Kent Heckenlively to her nationally syndicated radio program, The Sharon Kleyne ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... -- Immune Pharmaceuticals (NASDAQ: IMNP ) ("Immune"), ... will hold a Satellite Symposium on February 20th, 2017 at ... Munich, Germany . The ... for the maintenance of remission in AML with Ceplene" ... 2017 from 12:45 – 13:45 CET in Lecture Hall ...
(Date:1/17/2017)... , Jan 17, 2017 Research and Markets ... 2016-2020" report to their offering. ... The global laparotomy sponges market to grow ... Global Laparotomy Sponges Market 2016-2020, has been prepared based ... report covers the market landscape and its growth prospects over the ...
(Date:1/17/2017)... Minn. , Jan. 17, 2017  ANI ... today announced the appointment of Karen Quinn Ph.D ... 17, 2017.  Karen Quinn ... of leadership experience in Global Regulatory Affairs, specifically ... active pharmaceutical ingredients.  Dr. Quinn worked most recently ...
Breaking Medicine Technology: