Navigation Links
Transforming scar tissue into beating hearts: The next instalment
Date:4/1/2012

London -- The latest research developments to reprogram scar tissue resulting from myocardial infarction (MI) into viable heart muscle cells, were presented at the Frontiers in CardioVascular Biology (FCVB) 2012 meeting, held 30 March to 1 April at the South Kensington Campus of Imperial College in London.

In a keynote lecture Dr Deepak Srivastava outlined his approach that has been described as a "game changer" with the potential to revolutionise treatment of MI. For the first time at the FCVB meeting, Srivastava presented the results of his latest studies using viral vectors to deliver genes directly into the hearts of adult mice that had experienced an MI. The FCVB meeting was organised by the Council on Basic Cardiovascular Science (CBCS) of the European Society of Cardiology (ESC).

In his original "proof of principle" study, published August 2010 in "Cell", Srivastava was able to show that all that was needed for the direct reprogramming of fibroblasts (a major component of scar tissue) into myocytes (heart muscle cells responsible for beating) was the delivery of three genes. The work , which took place in a Petri dish, was considered groundbreaking since it showed for the first time that unrelated adult cells could be reprogrammed from one cell type to another without having to go all the way back to a stem cell state.

"Our ultimate hope is that, during the acute period following MI, patients will be able to receive direct injections of factors that transform the existing fibroblast cells in the "scar" into new myocytes. The resulting increase in muscle mass should help MI survivors to live more normal lives," explained Srivastava, who is director of the Gladstone Institute of Cardiovascular Disease in San Francisco, US.

Healthy heart tissue is composed of a mixture of several kinds of cells, including cardiomyocytes, which provide beating muscle, and cardiac fibroblasts, that provide architectural sup
'/>"/>

Contact: ESC Press Office
press@escardio.org
33-049-294-8627
European Society of Cardiology
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Palliative Care: Transforming the Care of Serious Illness
2. National committee releases findings on transforming and improving the nursing profession
3. Transforming medical implants
4. New study suggests stem cells sabotage their own DNA to produce new tissues
5. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
6. Step Up to Speak Up Events Use Spoken Word and African-American Greek Tradition of Stepping to Raise Awareness for Organ and Tissue Donation
7. CSMG Technologies, Inc. Engages New Team to Manage Live Tissue Connect, Inc.
8. Paired drugs kill precancerous colon polyps, spare normal tissue
9. Tissue engineers create a new way to assemble artificial tissues
10. Ultrasound could boost tissue implant success
11. Color-coded tracking method helps scientists analyze outcomes of newly transplanted tissue
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... of Texas MD Anderson Cancer Center today announced a ... breast screening at a network of community breast care ... late November, MD Anderson will become the exclusive provider ... Hermann,s 10 breast care centers, located in Memorial City, ... time, the network will expand to Memorial Hermann,s locations ...
(Date:8/21/2014)... 21, 2014 (HealthDay News) -- Black mothers are less ... here,s one possible reason why: Hospitals in neighborhoods with ... those in areas with more white residents, a U.S. ... are much less common in medical centers where the ... U.S. Centers for Disease Control and Prevention reported Thursday. ...
(Date:8/21/2014)... By Dennis Thompson ... (HealthDay News) -- A combination of therapy and antidepressants ... depression, a new study reports. Four out of ... two years experienced full recovery when treated with cognitive ... other hand, the combination didn,t work much better than ...
(Date:8/21/2014)... Seattle, WA chiropractors Dr. Lincoln ... Chiropractic and Massage Center have recently welcomed two ... Rina Lang, LMP and Mike Larios, LMP have specialized ... techniques, and have developed their expertise working in a ... important in a clinical environment where massage is used ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 The results ... today in The Journal of the American Medical Association ... invasive cancers and reduces unnecessary recalls. Memorial Healthcare System ... the study. , “This study confirms what we already ... harmful cancers we want to find and, at the ...
Breaking Medicine News(10 mins):Health News:MD Anderson and Memorial Hermann to operate breast screening network across Houston area 2Health News:Racial Disparities in Breast-Feeding May Start With Hospitals, Study Suggests 2Health News:Talk Therapy Plus Meds May Be Best for Severe Depression 2Health News:Talk Therapy Plus Meds May Be Best for Severe Depression 3Health News:Seattle’s Eastlake Chiropractic and Massage Center Is Pleased to Introduce Rina Lang and Mike Larios as New Members of Its Massage Therapy Team 2Health News:Seattle’s Eastlake Chiropractic and Massage Center Is Pleased to Introduce Rina Lang and Mike Larios as New Members of Its Massage Therapy Team 3Health News:Dr. Mary Hayes: Study Shows 3D Mammography Finds More Invasive Cancers While Reducing Unnecessary Recalls 2
... The More You Know, the More You Care About ... Action for World,s Leaders,to ,Put a Face on the ... 25 years,after HIV was discovered, one-third of the people ... about the global HIV and AIDS epidemic,and one-fourth believe ...
... Peninsula Medical School in the South West of England ... providing out of hours services in primary care are ... discussions and carried out telephone interviews with 27 patients ... general practice cover in the evenings and weekends in ...
... female hormone , THURSDAY, Nov. 29 (HealthDay News) -- ... given with estrogen in hormone replacement therapy -- offers ... , They conducted tests on female mice genetically engineered ... conclusion. , Treatment with estrogen blocked the Alzheimer,s-like symptoms ...
... 29 S3 Matching Technologies,patented TeraMatch(R) has ... (TMHP) innovative technology to automate the verification ... that Medicaid does not,allow payments to non-qualified ... TMHP relied on manual data verification searches ...
... to Create New, Database File Storage System to ... Nov. 29 ONStor Inc., the leading,provider of ... that Consortium Health Plans, Inc., a national consortium ... has chosen the ONStor,Bobcat Series NAS Gateway as ...
... STAAR Surgical,Company (Nasdaq: STAA ), a ... products, today announced that it will,present at the ... on,Tuesday, December 4, 2007 at the Millennium Broadway ... Surgical,s Chief Executive Officer, will,discuss the Company,s business ...
Cached Medicine News:Health News:AIDS Ignorance: One-Third of Adults Admit Little or No Knowledge of Pandemic 2Health News:AIDS Ignorance: One-Third of Adults Admit Little or No Knowledge of Pandemic 3Health News:AIDS Ignorance: One-Third of Adults Admit Little or No Knowledge of Pandemic 4Health News:Out-of-hours doctors reluctant to do home visits, say patients 2Health News:Progesterone Won't Shield Women Against Alzheimer's 2Health News:S3 Matching Technologies Aids in Reducing Risk to Texas Medicaid System 2Health News:Consortium Health Plans Cuts Down on Power Usage and Cooling in Its Data Center Using ONStor's Green Clustered NAS Solution 2Health News:Consortium Health Plans Cuts Down on Power Usage and Cooling in Its Data Center Using ONStor's Green Clustered NAS Solution 3Health News:STAAR Surgical to Present at the BMO Capital Markets Focus on Healthcare Conference 2
(Date:8/21/2014)... ARMONK , N.Y. and HAMBURG, Germany ... today announced it is collaborating with Deutsches Elektronen-Synchrotron ( ... Germany , to speed up management and ... Big Data and Analytics architecture based on ... gigabyte per second of data at peak performance and ...
(Date:8/21/2014)... 2014  ACI Clinical ( www.aciclinical.com ) announces ... Committees. Using this solution, trial sponsors ... standard costs and receive the same expertise that ... services. Leveraging a decade of DMC ... development, statistical programming and meeting facilitation), ACI analyzed ...
(Date:8/21/2014)... 21, 2014 CVS Caremark Corporation (NYSE: ... Yields and consideration payable in connection with its previously announced ... 2014 for (1) any and all of its 6.250% Senior ... up to a maximum amount of its 6.125% Senior Notes ... Notes due 2017 (collectively, the "Maximum Tender Offer Notes" and ...
Breaking Medicine Technology:DESY and IBM Develop Big Data Architecture for Science 2DESY and IBM Develop Big Data Architecture for Science 3ACI Clinical: Innovation and Savings in Data Safety Monitoring Committees 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 3CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 4CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 5CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 6
This free-standing work station safely ventilates fumes upwards, away from the work surface. Optional Exhaust Purification System features bonded charcoal filters that remove organic chemical vapors ...
... is the same as model ... flat internal baffle across the ... baffle slopes forward, leaving space ... sweep the deck and space ...
... The Benchtop Fume Hood is an ... installations in which a number of fume ... schools, junior colleges and universities. Features include ... polyethylene with rounded inside corners for easy ...
This is the second generation of the famous A/O sliding microtome, manufactured in the United States under the Leica trademark....
Medicine Products: