Navigation Links
Transforming scar tissue into beating hearts: The next instalment
Date:4/1/2012

London -- The latest research developments to reprogram scar tissue resulting from myocardial infarction (MI) into viable heart muscle cells, were presented at the Frontiers in CardioVascular Biology (FCVB) 2012 meeting, held 30 March to 1 April at the South Kensington Campus of Imperial College in London.

In a keynote lecture Dr Deepak Srivastava outlined his approach that has been described as a "game changer" with the potential to revolutionise treatment of MI. For the first time at the FCVB meeting, Srivastava presented the results of his latest studies using viral vectors to deliver genes directly into the hearts of adult mice that had experienced an MI. The FCVB meeting was organised by the Council on Basic Cardiovascular Science (CBCS) of the European Society of Cardiology (ESC).

In his original "proof of principle" study, published August 2010 in "Cell", Srivastava was able to show that all that was needed for the direct reprogramming of fibroblasts (a major component of scar tissue) into myocytes (heart muscle cells responsible for beating) was the delivery of three genes. The work , which took place in a Petri dish, was considered groundbreaking since it showed for the first time that unrelated adult cells could be reprogrammed from one cell type to another without having to go all the way back to a stem cell state.

"Our ultimate hope is that, during the acute period following MI, patients will be able to receive direct injections of factors that transform the existing fibroblast cells in the "scar" into new myocytes. The resulting increase in muscle mass should help MI survivors to live more normal lives," explained Srivastava, who is director of the Gladstone Institute of Cardiovascular Disease in San Francisco, US.

Healthy heart tissue is composed of a mixture of several kinds of cells, including cardiomyocytes, which provide beating muscle, and cardiac fibroblasts, that provide architectural sup
'/>"/>

Contact: ESC Press Office
press@escardio.org
33-049-294-8627
European Society of Cardiology
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Palliative Care: Transforming the Care of Serious Illness
2. National committee releases findings on transforming and improving the nursing profession
3. Transforming medical implants
4. New study suggests stem cells sabotage their own DNA to produce new tissues
5. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
6. Step Up to Speak Up Events Use Spoken Word and African-American Greek Tradition of Stepping to Raise Awareness for Organ and Tissue Donation
7. CSMG Technologies, Inc. Engages New Team to Manage Live Tissue Connect, Inc.
8. Paired drugs kill precancerous colon polyps, spare normal tissue
9. Tissue engineers create a new way to assemble artificial tissues
10. Ultrasound could boost tissue implant success
11. Color-coded tracking method helps scientists analyze outcomes of newly transplanted tissue
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... San Marcos, CA (PRWEB) May 27, 2015 ... a solution to help patients - who need extensive dental ... as well as treatment options customized for their problems. , ... consists in a visual presentation of the assessment of the ... most suitable options, which can treat their oral health problems. ...
(Date:5/27/2015)... The new http://www.carsonenergy.com includes ... should consider oil and gas investing, the substantial tax ... drilled, industry news, IRA investing, definitions and acronyms, info-graphics ... knowledge and experience is now in one central location, ... able to access 24 hours a day, 7 days ...
(Date:5/27/2015)... 2015 Black Book Rankings, well ... in the multiple services and software industries, conducted ... highest ranked Electronic Health and Medical Record software ... research focus on implemented EHR users, Black Book ... with the highest scores in client experience among ...
(Date:5/27/2015)... CURE® Magazine and the ... to advance research, provide information and support, and raise ... the fifth most common type of cancer, which begins ... grow out of control. , “CURE Magazine provides ... of the cancer experience through digital and print publications, ...
(Date:5/27/2015)... The MedSpa at Hendrick is excited to ... in Abilene, Texas: Xeomin®, Belotero Balance® and Radiesse®. , ... lines, better known as the lines between the eyebrows ... treat smoker’s lines around the mouth and marionette lines ... the appearance of smile lines or lines around the ...
Breaking Medicine News(10 mins):Health News:San Marcos Dentistry Office Offering a New Service Dental Case Planning 2Health News:Carson Energy Launches Next Generation Investor Website 2Health News:Cloud-Based Electronic Health Record firms sweep top physician satisfaction rankings for Small and Solo Practices, reveals 2015 Black Book survey 2Health News:Cloud-Based Electronic Health Record firms sweep top physician satisfaction rankings for Small and Solo Practices, reveals 2015 Black Book survey 3Health News:Cloud-Based Electronic Health Record firms sweep top physician satisfaction rankings for Small and Solo Practices, reveals 2015 Black Book survey 4Health News:CURE® Magazine and Bladder Cancer Advocacy Network Align to Increase Awareness of Fifth Most Common Type of Cancer 2Health News:CURE® Magazine and Bladder Cancer Advocacy Network Align to Increase Awareness of Fifth Most Common Type of Cancer 3Health News:The MedSpa at Hendrick Introduces Xeomin®, Belotero Balance® and Radiesse® Injectables 2
... to begin later this year -, BELLEVILLE, ... (TSX: BNC), a research-based, technology-driven Canadian,biopharmaceutical company, today ... Food and Drug Administration (FDA) that its therapy ... Fast Track,designation. A Phase III clinical trial comparing ...
... to continued need for mammograms , , TUESDAY, March 4 (HealthDay ... a woman stops taking combination hormone replacement therapy, a new ... 5 issue of the Journal of the American Medical ... Health Initiative (WHI). That trial was halted abruptly in 2002, ...
... March 4 Governor Edward G.,Rendell,s health care ... support for,the Governor,s Cover All Pennsylvanians continues to ... on cigarettes and tobacco products, there are,funds to ... Additionally, the team told the House of ...
... annual KID,HEALTHY--Steps to Healthy Living Campaign, SANTA ... trend of childhood obesity in Southern California schools, ... parents from Los Angeles,Orange, Riverside, San Bernardino, San ... participate in the KID HEALTHY--Steps to Healthy,Living Campaign. ...
... Learning, Arts, and the Brain, a study three ... by cognitive neuroscientists from seven leading universities in the ... today at a news conference at the Dana Foundations ... Are smart people drawn to the arts or does ...
... March 4 Metro Parent and Henry Ford Health,System ... TV,and movie personality, and best-selling author of Louder Than ... Detroit area. McCarthy will,be the keynote speaker at the ... Troy Hilton, an event designed to educate locals about ...
Cached Medicine News:Health News:Bioniche Receives Fast Track Designation For First-Line Bladder Cancer Therapy 2Health News:Bioniche Receives Fast Track Designation For First-Line Bladder Cancer Therapy 3Health News:Raised Breast Cancer Risk Persists After Combo HRT Stopped 2Health News:Raised Breast Cancer Risk Persists After Combo HRT Stopped 3Health News:Governor Rendell's Health Care Reform Cabinet Says Providing Access to Health Care for Pennsylvania's Uninsured is Within Reach 2Health News:Governor Rendell's Health Care Reform Cabinet Says Providing Access to Health Care for Pennsylvania's Uninsured is Within Reach 3Health News:Governor Rendell's Health Care Reform Cabinet Says Providing Access to Health Care for Pennsylvania's Uninsured is Within Reach 4Health News:Southern California Parents and Kids Take Healthy Steps in Tackling Childhood Obesity 2Health News:Southern California Parents and Kids Take Healthy Steps in Tackling Childhood Obesity 3Health News:Dana Foundation releases arts and cognition research 2Health News:TV Personality and Best-Selling Author Jenny McCarthy Comes to Detroit to Share Her Story of the Struggles and Triumphs of Raising Her Son, Evan, During a Day-Long Autism Workshop 2
(Date:5/27/2015)... 26, 2015 Research and Markets( http://www.researchandmarkets.com/research/ljsxt8/asia_pacific ) has ... Ray Devices Market - Growth, Trends And Forecasts (2014 - ... Asia Pacific market for Portable X-Ray ... 2014 to 2020 X-Ray is a form of ... the body, especially bones. The need of point of care ...
(Date:5/27/2015)... 2015 Research and Markets( http://www.researchandmarkets.com/research/nt9zlx/asia_pacific ) has ... Market - Growth, Trends And Forecasts (2014 - 2019)" ... is a detailed type of imaging that customs a ... called a mammogram, is used to support in the ... An x-ray (radiograph) is a noninvasive medical test that ...
(Date:5/27/2015)... senior marketing associate with the animal health division of Eli Lilly and ... setting in Bangkok, Thailand , will be among the ... respect and dignity is the guiding star for me and my fellow ... LillyPad blog . Donatelli and Lilly colleagues from ... , France , Ukraine ...
Breaking Medicine Technology:Asia Pacific Portable X Ray Devices Market 2015 - Trends And Forecasts to 2019 2Asia Pacific Mammography Market Trends and Forecasts 2015-2019 2Lilly Sends Employees to Serve in Vulnerable Communities around the World 2Lilly Sends Employees to Serve in Vulnerable Communities around the World 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: