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Transcatheter aortic valve implantation with the Edwards valve prosthesis in patients with low
Date:8/30/2011

loped to predict the operative mortality of coronary surgery).

In view of the overall good results in this high risk population, a significant trend to include lower risk patients in Europe has been observed. The last registries have seen their Euroscore decreasing to 15% and some prospective trials are planned to include patients whatever their Score.

"We sought to evaluate the results obtained in our subgroup of patients with a low Euroscore. It does not mean that the patients were at very low risk for TAVI, since they had been considered as having surgical contraindication which did not affect the Euroscore (radiotherapy, corticosteroids, thoracic deformation or porcelain aorta). However, the patients were often less sick and younger and it seemed interesting to assess the results in this population," said Dr Godin.

This study is a retrospective study from all 177 patients implanted with the Edwards prosthesis at the Rouen centre between May 2006 and January 2011. Patients were divided into two groups according to their predictive Logistic Euroscore: High Euroscore (>20%) vs Low Euroscore (<20%).

Results show that procedural success was 100% in the low Euroscore group versus 95.3% in the high Euroscore group (p=0.1).

The most interesting point to observe is the absence of death at one month in the low Euroscore group, versus a mortality rate of 11.1% in the high Euroscore group (>20%), (p < 0.04) and this result is confirmed at 1-year with 5 vs 24.8 %, (p<0.01)

While we were expecting a lower mortality among patients with low Euroscore, the observed difference was much greater than anticipated. In fact the mortality rates have approached the results with conventional surgery.

The results represent a first step towards a broader assessment of percutaneous techniques in populations at lower surgical risk but without forgetting that surgery is currently the gold standard


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Contact: Jacqueline Partarrieu
press@escardio.org
33-633-473-335
European Society of Cardiology
Source:Eurekalert

Page: 1 2

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