Navigation Links
Transcatheter aortic valve implantation with the Edwards valve prosthesis in patients with low
Date:8/30/2011

loped to predict the operative mortality of coronary surgery).

In view of the overall good results in this high risk population, a significant trend to include lower risk patients in Europe has been observed. The last registries have seen their Euroscore decreasing to 15% and some prospective trials are planned to include patients whatever their Score.

"We sought to evaluate the results obtained in our subgroup of patients with a low Euroscore. It does not mean that the patients were at very low risk for TAVI, since they had been considered as having surgical contraindication which did not affect the Euroscore (radiotherapy, corticosteroids, thoracic deformation or porcelain aorta). However, the patients were often less sick and younger and it seemed interesting to assess the results in this population," said Dr Godin.

This study is a retrospective study from all 177 patients implanted with the Edwards prosthesis at the Rouen centre between May 2006 and January 2011. Patients were divided into two groups according to their predictive Logistic Euroscore: High Euroscore (>20%) vs Low Euroscore (<20%).

Results show that procedural success was 100% in the low Euroscore group versus 95.3% in the high Euroscore group (p=0.1).

The most interesting point to observe is the absence of death at one month in the low Euroscore group, versus a mortality rate of 11.1% in the high Euroscore group (>20%), (p < 0.04) and this result is confirmed at 1-year with 5 vs 24.8 %, (p<0.01)

While we were expecting a lower mortality among patients with low Euroscore, the observed difference was much greater than anticipated. In fact the mortality rates have approached the results with conventional surgery.

The results represent a first step towards a broader assessment of percutaneous techniques in populations at lower surgical risk but without forgetting that surgery is currently the gold standard


'/>"/>

Contact: Jacqueline Partarrieu
press@escardio.org
33-633-473-335
European Society of Cardiology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Press registration now open for Transcatheter Valve Therapies
2. Early transcatheter valve recipient honored with Courageous Patient Award at TCT 2010
3. Simple new bedside screening effectively identifies patients with acute aortic dissection
4. University of Michigan Cardiovascular Center studies new treatment for high-risk aortic patients
5. Mount Sinai first in US to implant aortic valve prosthesis to treat severe aortic stenosis
6. Aortic aneurysm treatable with asthma drugs
7. Clinical trial establishes catheter-based aortic valve replacement as new standard of care
8. New treatment for severe aortic stenosis shown to save lives, Stanford researchers say
9. New Procedure for Aortic Valve Replacement Looks Promising
10. Amphetamine use increases risk of aortic tears in young adults, UT Southwestern researchers report
11. Regional protocols improve quality of care for aortic dissection patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015 Padre Murphy's and Owner Tom Boyle ... Pro Player Health Alliance (PPHA). The PPHA's passion for ... everyone, including NFL greats, treated for obstructive sleep apnea (OSA) ... supporting the cause in the valley. The most recent plans ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, has recently ... View website of AngelWeddingDress.com to find more details. ... online for a bridal party. AngelWeddingDress offers a variety ... Its maternity wedding dresses are specially designed for 2015. ...
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post explaining the ... . , Auto insurance quotes help many drivers find ... necessary to call an agent or visit an agency for ... single website: http://autocarinsurancebest.com/ . , Every business who relies ...
(Date:1/22/2015)... 2015 Yesterday, Senator Holly Mitchell ... Kristin Olsen (R-Modesto) were honored by the California ... biotechnology, biomedical science, medical device and pharmaceutical innovation ... the “2014 Life Sciences Champion” award from CHI ...
(Date:1/22/2015)... 22, 2015 EBSCO Information Services ... expanding their relationship in an effort to further promote visibility ... While EBSCO has long made AMA journals available via its ... for The JAMA Network. , Long known as ...
Breaking Medicine News(10 mins):Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4
... about microRNAs short strands of RNA that can ... it becomes how closely they are associated with cancer. ... and their colleagues have identified two microRNAs (miRNAs) that ... miRNAs may provide an early warning of metastatic breast ...
... findings apply to humans , , MONDAY, Jan. 28 (HealthDay News) ... a new study found. , The mice that were breast-fed ... the allergen and developed tolerance to it. , But once ... can be extrapolated to humans. , "You hate to ...
... 28 MaxCyte, Inc., a,clinical-stage therapeutic company ... systems, announces that Madhusudan V. Peshwa, Ph.D., ... present on Tuesday,January 29, 2008, at 11:35 ... Therapy,Forum in Washington, DC. Dr. Peshwa,s presentation ...
... of,President Bush,s final State of the Union address this ... that,should be undertaken this year to protect our nation,s ... unstable economy, the growing health,care crisis and very real ... on the president and Congress to:, -- Increase ...
... A new study, led by researchers at The ... that certain over-the-counter earwax softeners can cause severe inflammation ... results of the study, recently published in The Laryngoscope, ... , Patients often complain that wax is blocking their ...
... Preventive Medicine (ACPM) has found there is insufficient ... prostate screening with digital rectal examination (DRE) or ... (PSA). ACPM advises that clinicians caring for ... family history, should provide information about the potential ...
Cached Medicine News:Health News:2 microRNAs promote spread of tumor cells 2Health News:2 microRNAs promote spread of tumor cells 3Health News:Breast-Feeding Protected Mice From Asthma 2Health News:Breast-Feeding Protected Mice From Asthma 3Health News:MaxCyte to Present at the Phacilitate Cell and Gene Therapy Forum 2008 2Health News:APHA Says Investing in Healthy People and Communities Can Help Create a Healthy Economy 2
(Date:1/23/2015)... 2015  Lixte Biotechnology Holdings, Inc. (OTCQB: LIXT), announced that the ... Lixte,s lead compound, LB‑100, is being conducted, has been expanded ... Kovach , M.D., the founder and President of Lixte, said ... a single site. Accrual of patients, however, was slower than ...
(Date:1/23/2015)... , Jan. 23, 2015  CytoSorbents Corporation (NASDAQ ... its CytoSorb® extracorporeal cytokine adsorber to reduce deadly ... the receipt of $385,642, net of transaction costs, ... the Technology Business Tax Certificate Transfer Program sponsored ...
(Date:1/23/2015)... BOSTON , January 23, 2015 Heptares ... is delighted to announce that the Malcolm Campbell ... Congreve (Vice President of Chemistry), Fiona Marshall ... (Chief Executive Officer and co-founder) for the seminal contributions to ...
Breaking Medicine Technology:Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4
... 2007 - OXiGENE, Inc.,(NASDAQ: OXGN, XSSE: OXGN), a ... and eye,diseases, announced today the publication of two ... afternoon at the,Annual Meeting of the American Society ... abstract reports for the first time full data ...
... Presented at Annual Meeting of the American Society ... June 4, 2007 -- SciClone Pharmaceuticals,Inc. (Nasdaq:SCLN) and ... thymalfasin (ZADAXIN(r), thymosin,alpha 1) achieved its primary endpoint ... with stage IV malignant melanoma, the,most advanced form ...
Cached Medicine Technology:OXiGENE Abstracts Published in ASCO Program 2OXiGENE Abstracts Published in ASCO Program 3OXiGENE Abstracts Published in ASCO Program 4
... Designed and manufactured specifically ... MultiWash II delivers the ... demand. The MultiWash II ... dependable accuracy, while providing ...
... the determination of A1c is also designed to ... is a fully automated analyzer including primary tube ... in safety and positive identification. The analysis methodology ... be interference-free and to produce the lowest CV's ...
Micromat II Hemoglobin A1c instrument is an easy-to-use, accurate and precise instrument with an requirement of only 10 L of capillary or venous sample....
... Cascade M-4 is a manual hemostasis ... routine clotting assays - PTs, aPTTs, ... for easy, inexpensive, low-volume testing, this ... big on features, offering time and ...
Medicine Products: